4KVV
| Crystal structure of an alkylated Cys mutant of CC-Hex | Descriptor: | 6-HELIX COILED COIL CC-HEX-L24C PEPTIDE with an alkylated Cys mutation | Authors: | Burton, A.J, Agnew, C, Brady, R.L, Woolfson, D.N. | Deposit date: | 2013-05-23 | Release date: | 2013-08-21 | Last modified: | 2013-09-11 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Accessibility, Reactivity, and Selectivity of Side Chains within a Channel of de Novo Peptide Assembly. J.Am.Chem.Soc., 135, 2013
|
|
4KVU
| Crystal structure of a 6-helix coiled coil CC-Hex-L17C-W224BF | Descriptor: | 6-helix coiled coil CC-Hex-L17C-W224BF, GLYCEROL | Authors: | Burton, A.J, Agnew, C, Brady, R.L, Woolfson, D.N. | Deposit date: | 2013-05-23 | Release date: | 2013-08-21 | Last modified: | 2013-09-11 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Accessibility, Reactivity, and Selectivity of Side Chains within a Channel of de Novo Peptide Assembly. J.Am.Chem.Soc., 135, 2013
|
|
2CW1
| Solution structure of the de novo-designed lambda Cro fold protein | Descriptor: | SN4m | Authors: | Isogai, Y, Ito, Y, Ikeya, T, Shiro, Y, Ota, M. | Deposit date: | 2005-06-15 | Release date: | 2005-12-13 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Design of lambda Cro fold: solution structure of a monomeric variant of the de novo protein. J.Mol.Biol., 354, 2005
|
|
5KWX
| |
5KWO
| |
5KX2
| |
5KWZ
| |
5KX0
| |
5KWP
| |
5KX1
| |
5KVN
| |
5LFN
| Crystal structure of human chondroadherin | Descriptor: | CHLORIDE ION, Chondroadherin | Authors: | Ramisch, S, Pramhed, A, Logan, D.T. | Deposit date: | 2016-07-03 | Release date: | 2016-12-28 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of human chondroadherin: solving a difficult molecular-replacement problem using de novo models. Acta Crystallogr D Struct Biol, 73, 2017
|
|
5D9B
| Luciferin-regenerating enzyme solved by SIRAS using XFEL (refined against native data) | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Luciferin regenerating enzyme, MAGNESIUM ION | Authors: | Yamashita, K, Pan, D, Okuda, T, Murai, T, Kodan, A, Yamaguchi, T, Gomi, K, Kajiyama, N, Kato, H, Ago, H, Yamamoto, M, Nakatsu, T. | Deposit date: | 2015-08-18 | Release date: | 2015-09-23 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | An isomorphous replacement method for efficient de novo phasing for serial femtosecond crystallography. Sci Rep, 5, 2015
|
|
8B16
| |
8B15
| |
7JH5
| Co-LOCKR: de novo designed protein switch | Descriptor: | Co-LOCKR: de novo designed protein switch | Authors: | Bick, M.J, Lajoie, M.J, Boyken, S.E, Sankaran, B, Baker, D. | Deposit date: | 2020-07-20 | Release date: | 2020-09-02 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.103 Å) | Cite: | Designed protein logic to target cells with precise combinations of surface antigens. Science, 369, 2020
|
|
4KY3
| Three-dimensional Structure of the orthorhombic crystal of computationally designed insertion domain , Northeast Structural Genomics Consortium (NESG) Target OR327 | Descriptor: | designed protein OR327 | Authors: | Kuzin, A, Su, M, Seetharaman, J, Maglaqui, M, Xiao, R, Lee, D, Gleixner, J, Baker, D, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2013-05-28 | Release date: | 2013-06-19 | Last modified: | 2016-02-17 | Method: | X-RAY DIFFRACTION (2.964 Å) | Cite: | Precise assembly of complex beta sheet topologies from de novo designed building blocks. Elife, 4, 2015
|
|
2PI4
| T7RNAP complexed with a phi10 protein and initiating GTPs. | Descriptor: | 3'-DEOXY-GUANOSINE-5'-TRIPHOSPHATE, 5'-D(*CP*TP*TP*CP*CP*TP*AP*TP*AP*GP*TP*GP*AP*GP*TP*CP*GP*TP*AP*TP*TP*A)-3', 5'-D(*TP*AP*AP*TP*AP*CP*GP*AP*CP*TP*CP*AP*CP*T)-3', ... | Authors: | Kennedy, W.P, Momand, J.R, Yin, Y.W. | Deposit date: | 2007-04-12 | Release date: | 2007-06-19 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Mechanism for de novo RNA synthesis and initiating nucleotide specificity by t7 RNA polymerase. J.Mol.Biol., 370, 2007
|
|
2PI5
| T7 RNA polymerase complexed with a phi10 promoter | Descriptor: | 5'-D(*CP*TP*TP*C*CP*TP*AP*TP*AP*GP*TP*GP*AP*GP*TP*CP*GP*TP*AP*TP*TP*A)-3', 5'-D(*TP*AP*AP*TP*AP*CP*GP*AP*CP*TP*CP*AP*CP*T)-3', DNA-directed RNA polymerase | Authors: | Kennedy, W.P, Momand, J.R, Yin, Y.W. | Deposit date: | 2007-04-12 | Release date: | 2007-06-19 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Mechanism for de novo RNA synthesis and initiating nucleotide specificity by t7 RNA polymerase. J.Mol.Biol., 370, 2007
|
|
5U9T
| The Tris-thiolate Zn(II)S3Cl Binding Site Engineered by D-Cysteine Ligands in de Novo Three-stranded Coiled Coil Environment | Descriptor: | ACETATE ION, CHLORIDE ION, POLYETHYLENE GLYCOL (N=34), ... | Authors: | Ruckthong, L, Peacock, A.F.A, Stuckey, J.A, Pecoraro, V.L. | Deposit date: | 2016-12-18 | Release date: | 2017-04-26 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | d-Cysteine Ligands Control Metal Geometries within De Novo Designed Three-Stranded Coiled Coils. Chemistry, 23, 2017
|
|
8WM0
| Crystal structure of TNIK-thiopeptide wTP3 complex | Descriptor: | ADENOSINE, THIOPEPTIDE wTP3, TRAF2 and NCK-interacting protein kinase | Authors: | Hamada, K, Kobayashi, S, Vinogradov, A.A, Zhang, Y, Goto, Y, Suga, H, Ogata, K, Sengoku, T. | Deposit date: | 2023-10-01 | Release date: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | A Compact Reprogrammed Genetic Code for De Novo Discovery of Proteolytically Stable Thiopeptides. J.Am.Chem.Soc., 2024
|
|
5TPH
| Crystal structure of a de novo designed protein homodimer with curved beta-sheet | Descriptor: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, de novo NTF2 homodimer | Authors: | Basanta, B, Marcos, E, Oberdorfer, G, Chidyausiku, T.M, Sankaran, B, Baker, D. | Deposit date: | 2016-10-20 | Release date: | 2017-01-25 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.47 Å) | Cite: | Principles for designing proteins with cavities formed by curved beta sheets. Science, 355, 2017
|
|
5OER
| Hen egg-white lysozyme refined against 5000 9 keV diffraction patterns | Descriptor: | 10-((2R)-2-HYDROXYPROPYL)-1,4,7,10-TETRAAZACYCLODODECANE 1,4,7-TRIACETIC ACID, GADOLINIUM ATOM, Lysozyme C, ... | Authors: | Gorel, A, Schlichting, I. | Deposit date: | 2017-07-09 | Release date: | 2017-10-25 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Multi-wavelength anomalous diffraction de novo phasing using a two-colour X-ray free-electron laser with wide tunability. Nat Commun, 8, 2017
|
|
5U35
| Crystal structure of a de novo designed protein with curved beta-sheet | Descriptor: | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 2-METHOXYETHANOL, CHLORIDE ION, ... | Authors: | Oberdorfer, G, Marcos, E, Basanta, B, Chidyausiku, T.M, Sankaran, B, Zwart, P.H, Baker, D. | Deposit date: | 2016-12-01 | Release date: | 2017-01-25 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Principles for designing proteins with cavities formed by curved beta sheets. Science, 355, 2017
|
|
5NNL
| |