7JH5

Co-LOCKR: de novo designed protein switch

Summary for 7JH5

Entry DOI	10.2210/pdb7jh5/pdb
Descriptor	Co-LOCKR: de novo designed protein switch (2 entities in total)
Functional Keywords	helical bundle, protein switch, de novo protein
Biological source	synthetic construct
Total number of polymer chains	2
Total formula weight	65759.66
Authors	Bick, M.J.,Lajoie, M.J.,Boyken, S.E.,Sankaran, B.,Baker, D. (deposition date: 2020-07-20, release date: 2020-09-02, Last modification date: 2024-04-03)
Primary citation	Lajoie, M.J.,Boyken, S.E.,Salter, A.I.,Bruffey, J.,Rajan, A.,Langan, R.A.,Olshefsky, A.,Muhunthan, V.,Bick, M.J.,Gewe, M.,Quijano-Rubio, A.,Johnson, J.,Lenz, G.,Nguyen, A.,Pun, S.,Correnti, C.E.,Riddell, S.R.,Baker, D. Designed protein logic to target cells with precise combinations of surface antigens. Science, 369:1637-1643, 2020 Cited by PubMed: 32820060 DOI: 10.1126/science.aba6527 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.103 Å)

Structure validation