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7QK5
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BU of 7qk5 by Molmil
In vitro assembled 266/297 - 391 tau filaments with KCl (10a)
Descriptor: CHLORIDE ION, Microtubule-associated protein tau, POTASSIUM ION
Authors:Lovestam, S, Scheres, S.H.W.
Deposit date:2021-12-17
Release date:2022-02-16
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (1.92 Å)
Cite:Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
2XTH
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BU of 2xth by Molmil
K2PtBr6 binding to lysozyme
Descriptor: HEXABROMOPLATINATE(IV), LYSOZYME C
Authors:Helliwell, J.R, Bell, A.M.T, Bryant, P, Fisher, S, Habash, J, Helliwell, M, Margiolaki, I, Kaenket, S, Watier, Y, Wright, J, Yalamanchili, S.K.
Deposit date:2010-10-07
Release date:2010-12-08
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Time-Dependent Analysis of K2Ptbr6 Binding to Lysozyme Studied by Protein Powder and Single Crystal X-Ray Analysis
Z.Kristallogr., 225, 2010
7EP1
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BU of 7ep1 by Molmil
Crystal structure of ZYG11B bound to GFLH degron
Descriptor: Protein zyg-11 homolog B
Authors:Yan, X, Li, Y.
Deposit date:2021-04-26
Release date:2021-07-14
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.852 Å)
Cite:Molecular basis for recognition of Gly/N-degrons by CRL2 ZYG11B and CRL2 ZER1 .
Mol.Cell, 81, 2021
7QKZ
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BU of 7qkz by Molmil
In vitro assembled 305-379 tau filaments (27a)
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W.
Deposit date:2021-12-19
Release date:2022-02-16
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (2.65 Å)
Cite:Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
7QJY
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BU of 7qjy by Molmil
In vitro assembled 266/297 - 391 tau filaments with LiCl (9a)
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W.
Deposit date:2021-12-17
Release date:2022-02-16
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.14 Å)
Cite:Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
2MBH
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BU of 2mbh by Molmil
NMR structure of EKLF(22-40)/Ubiquitin Complex
Descriptor: Krueppel-like factor 1, Ubiquitin
Authors:Raiola, L, Omichinski, J.G.
Deposit date:2013-07-31
Release date:2013-10-09
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural Characterization of a Noncovalent Complex between Ubiquitin and the Transactivation Domain of the Erythroid-Specific Factor EKLF.
Structure, 21, 2013
7QKX
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BU of 7qkx by Molmil
In vitro assembled 266/297 - 391 tau filaments with MgSO4 and NaCl (15b)
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W.
Deposit date:2021-12-19
Release date:2022-02-16
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.16 Å)
Cite:Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
7QJZ
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BU of 7qjz by Molmil
In vitro assembled 266/297 - 391 tau filaments with LiCl (9b)
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W.
Deposit date:2021-12-17
Release date:2022-02-16
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
7QHB
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BU of 7qhb by Molmil
Active state of GluA1/2 in complex with TARP gamma 8, L-glutamate and CTZ
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2,3-dihydroxypropyl (7Z)-hexadec-7-enoate, CYCLOTHIAZIDE, ...
Authors:Herguedas, B, Kohegyi, B, Zhang, D, Greger, I.H.
Deposit date:2021-12-11
Release date:2022-02-23
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Mechanisms underlying TARP modulation of the GluA1/2-gamma 8 AMPA receptor.
Nat Commun, 13, 2022
7SS1
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BU of 7ss1 by Molmil
The structure of NTMT1 in complex with compound GD433
Descriptor: (1R,3S,4R)-1-azabicyclo[2.2.2]octan-3-yl {2-[2-(4-fluoro-3-hydroxyphenyl)-1,3-thiazol-4-yl]propan-2-yl}carbamate, N-terminal Xaa-Pro-Lys N-methyltransferase 1, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Yadav, R, Guangping, D, Deng, Y, Huang, R, Noinaj, N.
Deposit date:2021-11-09
Release date:2022-11-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Discovery of a first-in-class small molecule inhibitor for Protein N-terminal methyltransferases 1/2
To Be Published
7QKY
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BU of 7qky by Molmil
In vitro assembled 0N4R tau filaments with phosphoserine (47a)
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W.
Deposit date:2021-12-19
Release date:2022-02-16
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (1.86 Å)
Cite:Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
7L3M
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BU of 7l3m by Molmil
PEPCK MMQX structure 40ms post-mixing with oxaloacetic acid
Descriptor: CARBON DIOXIDE, GUANOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ...
Authors:Clinger, J.A, Moreau, D.W, McLeod, M.J, Holyoak, T, Thorne, R.E.
Deposit date:2020-12-18
Release date:2021-10-13
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Millisecond mix-and-quench crystallography (MMQX) enables time-resolved studies of PEPCK with remote data collection.
Iucrj, 8, 2021
3II6
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BU of 3ii6 by Molmil
Structure of human Xrcc4 in complex with the tandem BRCT domains of DNA LigaseIV.
Descriptor: CHLORIDE ION, DNA ligase 4, DNA repair protein XRCC4
Authors:Meesala, S, Junop, M.
Deposit date:2009-07-31
Release date:2009-08-11
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural and functional interaction between the human DNA repair proteins DNA ligase IV and XRCC4
MOL.CELL.BIOL., 11, 2009
2XRC
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BU of 2xrc by Molmil
Human complement factor I
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, HUMAN COMPLEMENT FACTOR I
Authors:Roversi, P, Johnson, S, Lea, S.M.
Deposit date:2010-09-13
Release date:2011-07-13
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Structural Basis for Complement Factor I Control and its Disease-Associated Sequence Polymorphisms.
Proc.Natl.Acad.Sci.USA, 108, 2011
7QHH
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BU of 7qhh by Molmil
Desensitized state of GluA1/2 AMPA receptor in complex with TARP-gamma 8 (TMD-LBD)
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2,3-dihydroxypropyl (7Z)-hexadec-7-enoate, GLUTAMIC ACID, ...
Authors:Herguedas, B, Kohegyi, B, Dohrke, J.N, Watson, J.F, Zhang, D, Ho, H, Shaikh, S, Lape, R, Krieger, J.M, Greger, I.H.
Deposit date:2021-12-12
Release date:2022-02-23
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Mechanisms underlying TARP modulation of the GluA1/2-gamma 8 AMPA receptor.
Nat Commun, 13, 2022
7F77
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BU of 7f77 by Molmil
Crystal structure of glutamate dehydrogenase 3 from Candida albicans
Descriptor: Glutamate dehydrogenase
Authors:Li, N, Wang, W, Zeng, X, Liu, M, Li, M, Li, C, Wang, M.
Deposit date:2021-06-28
Release date:2021-07-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.086 Å)
Cite:Crystal structure of glutamate dehydrogenase 3 from Candida albicans.
Biochem.Biophys.Res.Commun., 570, 2021
2MJL
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BU of 2mjl by Molmil
Solution structure of peptidyl-tRNA hyrolase from Vibrio cholerae
Descriptor: Peptidyl-tRNA hydrolase
Authors:Kabra, A, Shahid, S, Yadav, R, Pulavarti, S, Shukla, V.K, Arora, A.
Deposit date:2014-01-11
Release date:2015-01-21
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution structure of peptidyl-tRNA hydrolase from Vibrio cholerae
To be Published
7KG9
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BU of 7kg9 by Molmil
Dihydrodipicolinate synthase (DHDPS) from C.jejuni, H56W mutant with pyruvate bound in the active site and L-lysine bound at the allosteric site
Descriptor: 1,2-ETHANEDIOL, 4-hydroxy-tetrahydrodipicolinate synthase, ACETATE ION, ...
Authors:Saran, S, Majdi Yazdi, M, Sanders, D.A.R.
Deposit date:2020-10-16
Release date:2021-10-20
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Fluorescence-based Assay Development for Screening Novel Inhibitors of Dihydrodipicolinate Synthase from Campylobacter jejuni
To Be Published
7AZX
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BU of 7azx by Molmil
Crystal structure of the MIZ1-BTB-domain in complex with a HUWE1-derived peptide
Descriptor: E3 ubiquitin-protein ligase HUWE1, Zinc finger and BTB domain-containing protein 17 isoform X1
Authors:Orth, B, Sander, B, Diederichs, K, Lorenz, S.
Deposit date:2020-11-17
Release date:2021-06-30
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Identification of an atypical interaction site in the BTB domain of the MYC-interacting zinc-finger protein 1.
Structure, 29, 2021
7AYR
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BU of 7ayr by Molmil
Crystal structure of DPP8 in complex with a 4-oxo-b-lactam based inhibitor, B115
Descriptor: Dipeptidyl peptidase 8, PHOSPHATE ION, trimethylamine oxide, ...
Authors:Ross, B.H, Huber, R.
Deposit date:2020-11-13
Release date:2021-06-30
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Chemoproteomics-Enabled Identification of 4-Oxo-beta-Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9.
Angew.Chem.Int.Ed.Engl., 2022
5L1V
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BU of 5l1v by Molmil
X-ray Structure of M81C mutant of Cytochrome P450 PntM with pentalenolactone F
Descriptor: PROTOPORPHYRIN IX CONTAINING FE, Pentalenolactone synthase, pentalenolactone F
Authors:Duan, L, Jogl, G, Cane, D.E.
Deposit date:2016-07-29
Release date:2016-09-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:The Cytochrome P450-Catalyzed Oxidative Rearrangement in the Final Step of Pentalenolactone Biosynthesis: Substrate Structure Determines Mechanism.
J.Am.Chem.Soc., 138, 2016
7AKP
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BU of 7akp by Molmil
Crystal structure of E. coli RNA helicase HrpA-D305A
Descriptor: ATP-dependent RNA helicase HrpA
Authors:Grass, L.M, Wollenhaupt, J, Barthel, T, Loll, B, Wahl, M.C.
Deposit date:2020-10-01
Release date:2021-06-30
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Large-scale ratcheting in a bacterial DEAH/RHA-type RNA helicase that modulates antibiotics susceptibility.
Proc.Natl.Acad.Sci.USA, 118, 2021
7AYQ
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BU of 7ayq by Molmil
Crystal structure of DPP8 in complex with a 4-oxo-b-lactam based inhibitor, B114
Descriptor: Dipeptidyl peptidase 8, GLYCEROL, PHOSPHATE ION, ...
Authors:Ross, B, Huber, R.
Deposit date:2020-11-13
Release date:2021-06-30
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Chemoproteomics-Enabled Identification of 4-Oxo-beta-Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9.
Angew.Chem.Int.Ed.Engl., 2022
7L3J
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BU of 7l3j by Molmil
T4 Lysozyme L99A - benzylacetate - RT
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BETA-MERCAPTOETHANOL, CHLORIDE ION, ...
Authors:Fischer, M, Bradford, S.Y.C.
Deposit date:2020-12-17
Release date:2021-10-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Temperature artifacts in protein structures bias ligand-binding predictions.
Chem Sci, 12, 2021
7Q86
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BU of 7q86 by Molmil
Crystal structure of human peroxisomal acyl-Co-A oxidase 1a, FAD-bound-form
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Isoform 2 of Peroxisomal acyl-coenzyme A oxidase 1
Authors:Sonani, R.R, Blat, A, Dubin, G.
Deposit date:2021-11-10
Release date:2022-03-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Crystal structures of apo- and FAD-bound human peroxisomal acyl-CoA oxidase provide mechanistic basis explaining clinical observations.
Int.J.Biol.Macromol., 205, 2022

224004

数据于2024-08-21公开中

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