7AZX
Crystal structure of the MIZ1-BTB-domain in complex with a HUWE1-derived peptide
Summary for 7AZX
| Entry DOI | 10.2210/pdb7azx/pdb |
| Descriptor | Zinc finger and BTB domain-containing protein 17 isoform X1, E3 ubiquitin-protein ligase HUWE1 (3 entities in total) |
| Functional Keywords | btb-domain, huwe1, transcription factor, dimer, transcription |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 3 |
| Total formula weight | 29727.10 |
| Authors | Orth, B.,Sander, B.,Diederichs, K.,Lorenz, S. (deposition date: 2020-11-17, release date: 2021-06-30, Last modification date: 2024-01-31) |
| Primary citation | Orth, B.,Sander, B.,Moglich, A.,Diederichs, K.,Eilers, M.,Lorenz, S. Identification of an atypical interaction site in the BTB domain of the MYC-interacting zinc-finger protein 1. Structure, 29:1230-1240.e5, 2021 Cited by PubMed: 34186024DOI: 10.1016/j.str.2021.06.005 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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