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7KG9

Dihydrodipicolinate synthase (DHDPS) from C.jejuni, H56W mutant with pyruvate bound in the active site and L-lysine bound at the allosteric site

Summary for 7KG9
Entry DOI10.2210/pdb7kg9/pdb
Descriptor4-hydroxy-tetrahydrodipicolinate synthase, 1,2-ETHANEDIOL, TRIETHYLENE GLYCOL, ... (10 entities in total)
Functional Keywordsdihydrodipicolinate synthase, lyase
Biological sourceCampylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)
Total number of polymer chains6
Total formula weight209286.35
Authors
Saran, S.,Majdi Yazdi, M.,Sanders, D.A.R. (deposition date: 2020-10-16, release date: 2021-10-20, Last modification date: 2023-11-29)
Primary citationMajdi Yazd, M.,Reddy Annadi, K.,Saran, S.,Bhagwat, A.,Sanders, D.A.R.,Palmer, D.R.J.
Fluorescence-based Assay Development for Screening Novel Inhibitors of Dihydrodipicolinate Synthase from Campylobacter jejuni
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.06 Å)
Structure validation

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