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7QK5

In vitro assembled 266/297 - 391 tau filaments with KCl (10a)

Summary for 7QK5
Entry DOI10.2210/pdb7qk5/pdb
EMDB information14038
DescriptorMicrotubule-associated protein tau, CHLORIDE ION, POTASSIUM ION (3 entities in total)
Functional Keywordsalzheimer's disease, amyloid, tau, neurodegeneration, chronic traumatic encephalopathy, protein fibril
Biological sourceHomo sapiens (human)
Total number of polymer chains9
Total formula weight414620.76
Authors
Lovestam, S.,Scheres, S.H.W. (deposition date: 2021-12-17, release date: 2022-02-16, Last modification date: 2022-03-16)
Primary citationLovestam, S.,Koh, F.A.,van Knippenberg, B.,Kotecha, A.,Murzin, A.G.,Goedert, M.,Scheres, S.H.W.
Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11:-, 2022
Cited by
PubMed: 35244536
DOI: 10.7554/eLife.76494
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (1.92 Å)
Structure validation

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