3II6
Structure of human Xrcc4 in complex with the tandem BRCT domains of DNA LigaseIV.
Summary for 3II6
Entry DOI | 10.2210/pdb3ii6/pdb |
Descriptor | DNA repair protein XRCC4, DNA ligase 4, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | xrcc4, dna ligase iv, nhej, dna repair, brct, alternative splicing, coiled coil, dna damage, dna recombination, isopeptide bond, nucleus, phosphoprotein, polymorphism, ubl conjugation, atp-binding, cell cycle, cell division, disease mutation, dna replication, ligase, magnesium, metal-binding, nucleotide-binding, scid, ligase-dna binding protein complex, ligase/dna binding protein |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: Q13426 P49917 |
Total number of polymer chains | 6 |
Total formula weight | 154211.77 |
Authors | Meesala, S.,Junop, M. (deposition date: 2009-07-31, release date: 2009-08-11, Last modification date: 2024-02-21) |
Primary citation | Wu, P.Y.,Frit, P.,Meesala, S.,Dauvillier, S.,Modesti, M.,Andres, S.N.,Huang, Y.,Sekiguchi, J.,Calsou, P.,Salles, B.,Junop, M.S. Structural and functional interaction between the human DNA repair proteins DNA ligase IV and XRCC4 MOL.CELL.BIOL., 11:3163-3172, 2009 Cited by PubMed: 19332554PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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