3II6
Structure of human Xrcc4 in complex with the tandem BRCT domains of DNA LigaseIV.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0006302 | biological_process | double-strand break repair |
| A | 0006310 | biological_process | DNA recombination |
| B | 0003677 | molecular_function | DNA binding |
| B | 0005634 | cellular_component | nucleus |
| B | 0006302 | biological_process | double-strand break repair |
| B | 0006310 | biological_process | DNA recombination |
| C | 0003677 | molecular_function | DNA binding |
| C | 0005634 | cellular_component | nucleus |
| C | 0006302 | biological_process | double-strand break repair |
| C | 0006310 | biological_process | DNA recombination |
| D | 0003677 | molecular_function | DNA binding |
| D | 0005634 | cellular_component | nucleus |
| D | 0006302 | biological_process | double-strand break repair |
| D | 0006310 | biological_process | DNA recombination |
| X | 0003677 | molecular_function | DNA binding |
| X | 0003910 | molecular_function | DNA ligase (ATP) activity |
| X | 0005524 | molecular_function | ATP binding |
| X | 0006281 | biological_process | DNA repair |
| Y | 0003677 | molecular_function | DNA binding |
| Y | 0003910 | molecular_function | DNA ligase (ATP) activity |
| Y | 0005524 | molecular_function | ATP binding |
| Y | 0006281 | biological_process | DNA repair |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL Y 301 |
| Chain | Residue |
| Y | GLY669 |
| Y | LYS675 |
| site_id | AC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL Y 302 |
| Chain | Residue |
| Y | TRP738 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 136 |
| Details | Coiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphoserine; by PRKDC","evidences":[{"source":"PubMed","id":"14599745","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphoserine; by PRKDC","evidences":[{"source":"PubMed","id":"14599745","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22228831","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28500754","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 206 |
| Details | Domain: {"description":"BRCT 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00033","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 89 |
| Details | Domain: {"description":"BRCT 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00033","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
