PDB: 46188 resultsInfo pagesStatus searchChemie searchBIRD

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4R1M	Crystal structure of a Putative Acyl-CoA ligase (BT_0428) from Bacteroides thetaiotaomicron VPI-5482 at 2.48 A resolution Descriptor: 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, CHLORIDE ION, ... Authors: Joint Center for Structural Genomics (JCSG) Deposit date: 2014-08-06 Release date: 2014-08-27 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.48 Å) Cite: Crystal structure of a Hypothetical Acyl-CoA ligase (BT_0428) from Bacteroides thetaiotaomicron VPI-5482 at 2.48 A resolution To be published
5OGB	Human Cellular Retinoic Acid Binding Protein II (CRABPII) with bound synthetic retinoid DC360. Descriptor: 4-[2-(4,4-dimethyl-1-propan-2-yl-quinolin-6-yl)ethynyl]benzoic acid, Cellular retinoic acid-binding protein 2 Authors: Chisholm, D, Tomlinson, C, Whiting, A, Pohl, E. Deposit date: 2017-07-12 Release date: 2018-10-24 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Fluorescent Retinoic Acid Analogues as Probes for Biochemical and Intracellular Characterization of Retinoid Signaling Pathways. Acs Chem.Biol., 14, 2019
7CFP	Crystal structure of WDR5 in complex with a H3Q5ser peptide Descriptor: H3Q5ser peptide, SEROTONIN, WD repeat-containing protein 5 Authors: Zhao, J, Zhang, X, Zang, J. Deposit date: 2020-06-27 Release date: 2021-07-07 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Structural insights into the recognition of histone H3Q5 serotonylation by WDR5. Sci Adv, 7, 2021
2YCB	Structure of the archaeal beta-CASP protein with N-terminal KH domains from Methanothermobacter thermautotrophicus Descriptor: CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR, PHOSPHATE ION, POTASSIUM ION, ... Authors: Silva, A.P.G, Chechik, M, Byrne, R.T, Waterman, D.G, Ng, C.L, Dodson, E.J, Koonin, E.V, Antson, A.A, Smits, C. Deposit date: 2011-03-13 Release date: 2011-05-25 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Structure and Activity of a Novel Archaeal Beta-Casp Protein with N-Terminal Kh Domains. Structure, 19, 2011
7CFQ	Crystal structure of WDR5 in complex with H3K4me3Q5ser peptide Descriptor: 1,2-ETHANEDIOL, GLYCEROL, H3K4me3Q5ser peptide, ... Authors: Zhao, J, Zhang, X, Zang, J. Deposit date: 2020-06-27 Release date: 2021-07-07 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Structural insights into the recognition of histone H3Q5 serotonylation by WDR5. Sci Adv, 7, 2021
5O8I	Crystal structure of human histidine triad nucleotide-binding protein 1 (hHINT1) crystallized at P212121 space group, and refined to 1.27 A Descriptor: ADENOSINE-5'-DIPHOSPHATE, Histidine triad nucleotide-binding protein 1 Authors: Dolot, R.M, Seda, A, Nawrot, B.C. Deposit date: 2017-06-13 Release date: 2017-06-28 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.27 Å) Cite: Differences in crystal packing as the key factor for stabilization of the N-terminal fragment of hHINT1 protein To Be Published
3DPJ	The crystal structure of a TetR transcription regulator from Silicibacter pomeroyi DSS Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Transcription regulator, ... Authors: Tan, K, Li, H, Freeman, L, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) Deposit date: 2008-07-08 Release date: 2008-09-02 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (1.9 Å) Cite: The crystal structure of a TetR transcription regulator from Silicibacter pomeroyi DSS To be Published
6IFR	Type III-A Csm complex, Cryo-EM structure of Csm-NTR, ATP bound Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Type III-A CRISPR-associated RAMP protein Csm3, ... Authors: You, L, Ma, J, Wang, J, Zhang, X, Wang, Y. Deposit date: 2018-09-21 Release date: 2018-12-12 Last modified: 2019-01-23 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference Cell, 176, 2019
2YLY	Sulfonamides as selective Estrogen Receptor beta Agonists. Descriptor: ESTROGEN RECEPTOR BETA, N-cyclopropyl-4-oxidanyl-N-[(2R)-2-oxidanyl-2-phenyl-propyl]benzenesulfonamide, SULFATE ION Authors: Roberts, L.R, Armour, D, Barker, C, Bazin, R, Bess, K, Brown, A, Favor, D, Ellis, D, MacKenny, M, Pullen, N, Stennett, A, Strand, L, Styles, M, Phillips, C. Deposit date: 2011-06-06 Release date: 2012-06-13 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Sulfonamides as Selective Oestrogen Receptor Beta Agonists. Bioorg.Med.Chem.Lett., 21, 2011
4QTS	Crystal structure of Csm3-Csm4 subcomplex in the type III-A CRISPR-Cas interference complex Descriptor: CRISPR type III-associated RAMP protein Csm3, CRISPR type III-associated RAMP protein Csm4, ZINC ION Authors: Numata, T, Inanaga, H, Osawa, T. Deposit date: 2014-07-09 Release date: 2014-12-24 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (3.105 Å) Cite: Crystal structure of the Csm3-Csm4 subcomplex in the type III-A CRISPR-Cas interference complex. J.Mol.Biol., 427, 2015
6IFK	Cryo-EM structure of type III-A Csm-CTR1 complex, AMPPNP bound Descriptor: CTR1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... Authors: You, L, Ma, J, Wang, J, Zhang, X, Wang, Y. Deposit date: 2018-09-20 Release date: 2018-12-12 Last modified: 2019-01-23 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference Cell, 176, 2019
6GSL	Structure of T. thermophilus 70S ribosome complex with mRNA, tRNAfMet and cognate tRNAArg in the A-site Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... Authors: Rozov, A, Yusupov, M, Yusupova, G. Deposit date: 2018-06-14 Release date: 2018-07-04 Last modified: 2018-09-05 Method: X-RAY DIFFRACTION (3.16 Å) Cite: Tautomeric G•U pairs within the molecular ribosomal grip and fidelity of decoding in bacteria. Nucleic Acids Res., 46, 2018
3B0T	Human VDR ligand binding domain in complex with maxacalcitol Descriptor: (1S,3R,5Z,7E,14beta,17alpha,20S)-20-(3-hydroxy-3-methylbutoxy)-9,10-secopregna-5,7,10-triene-1,3-diol, SULFATE ION, Vitamin D3 receptor Authors: Hishiki, A, Hashimoto, H, Sato, M, Shimizu, T. Deposit date: 2011-06-14 Release date: 2011-08-10 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Human VDR ligand binding domain in complex with maxacalcitol To be Published
5NU5	Crystal structure of the human bromodomain of EP300 bound to the inhibitor XDM-CBP Descriptor: 1,2-ETHANEDIOL, Histone acetyltransferase p300, ~{N}-[[2,8-bis(oxidanyl)naphthalen-1-yl]methyl]-4-ethanoyl-3-ethyl-5-methyl-1~{H}-pyrrole-2-carboxamide Authors: Huegle, M, Wohlwend, D. Deposit date: 2017-04-28 Release date: 2017-08-16 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Beyond the BET Family: Targeting CBP/p300 with 4-Acyl Pyrroles. Angew. Chem. Int. Ed. Engl., 56, 2017
6GSK	Structure of T. thermophilus 70S ribosome complex with mRNA, tRNAfMet and near-cognate tRNAThr in the A-site Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... Authors: Rozov, A, Yusupov, M, Yusupova, G. Deposit date: 2018-06-14 Release date: 2018-07-04 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (3.36 Å) Cite: Tautomeric G•U pairs within the molecular ribosomal grip and fidelity of decoding in bacteria. Nucleic Acids Res., 46, 2018
7DNO	Characterization of Peptide Ligands Against WDR5 Isolated Using Phage Display Technique Descriptor: CYS-ARG-THR-LEU-PRO-PHE, WD repeat-containing protein 5 Authors: Cao, J, Cao, D, Xiong, B, Li, Y, Fan, T. Deposit date: 2020-12-10 Release date: 2021-02-10 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.03 Å) Cite: Phage-Display Based Discovery and Characterization of Peptide Ligands against WDR5. Molecules, 26, 2021
3S3I	p38 kinase crystal structure in complex with small molecule inhibitor Descriptor: 3-(3-tert-butyl[1,2,4]triazolo[4,3-a]pyridin-7-yl)-N-cyclopropyl-4-methylbenzamide, Mitogen-activated protein kinase 14 Authors: Segarra, V, Aiguade, J, Roca, R, Fisher, M, Lamers, M. Deposit date: 2011-05-18 Release date: 2012-04-04 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Novel triazolopyridylbenzamides as potent and selective p38 alpha inhibitors. Bioorg.Med.Chem.Lett., 22, 2012
3AUQ	Crystal structure of the human vitamin D receptor ligand binding domain complexed with Yne-diene type analog of active 14-epi-2alpha-methyl-19-norvitamin D3 Descriptor: (1R,2S,3R)-5-[2-[(1R,3aS,7aR)-1-[(2R)-6-hydroxy-6-methyl-heptan-2-yl]-7a-methyl-1,2,3,3a,6,7-hexahydroinden-4-yl]ethynyl]-2-methyl-cyclohex-4-ene-1,3-diol, Vitamin D3 receptor Authors: Kakuda, S, Takimoto-Kamimura, M. Deposit date: 2011-02-15 Release date: 2011-09-14 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.64 Å) Cite: Development of 14-epi-19-nortachysterol and its unprecedented binding configuration for the human vitamin D receptor J.Am.Chem.Soc., 133, 2011
7PEB	cryo-EM structure of DEPTOR bound to human mTOR complex 1, focussed on one protomer Descriptor: DEP domain-containing mTOR-interacting protein, INOSITOL HEXAKISPHOSPHATE, Regulatory-associated protein of mTOR, ... Authors: Waelchli, M, Maier, T. Deposit date: 2021-08-09 Release date: 2021-09-08 Last modified: 2024-07-17 Method: ELECTRON MICROSCOPY (3.67 Å) Cite: Regulation of human mTOR complexes by DEPTOR. Elife, 10, 2021
7PE7	cryo-EM structure of DEPTOR bound to human mTOR complex 2, overall refinement Descriptor: ACETYL GROUP, DEP domain-containing mTOR-interacting protein, INOSITOL HEXAKISPHOSPHATE, ... Authors: Waelchli, M, Maier, T. Deposit date: 2021-08-09 Release date: 2021-09-15 Last modified: 2021-09-29 Method: ELECTRON MICROSCOPY (3.41 Å) Cite: Regulation of human mTOR complexes by DEPTOR. Elife, 10, 2021
7PEC	cryo-EM structure of DEPTOR bound to human mTOR complex 1, DEPt-bound subset local refinement Descriptor: DEP domain-containing mTOR-interacting protein, INOSITOL HEXAKISPHOSPHATE, Regulatory-associated protein of mTOR, ... Authors: Waelchli, M, Maier, T. Deposit date: 2021-08-09 Release date: 2021-09-08 Last modified: 2024-07-17 Method: ELECTRON MICROSCOPY (4.24 Å) Cite: Regulation of human mTOR complexes by DEPTOR. Elife, 10, 2021
7PE9	cryo-EM structure of DEPTOR bound to human mTOR complex 2, DEPt-bound subset local refinement Descriptor: ACETYL GROUP, DEP domain-containing mTOR-interacting protein, INOSITOL HEXAKISPHOSPHATE, ... Authors: Waelchli, M, Maier, T. Deposit date: 2021-08-09 Release date: 2021-09-08 Last modified: 2021-09-29 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Regulation of human mTOR complexes by DEPTOR. Elife, 10, 2021
7PE8	cryo-EM structure of DEPTOR bound to human mTOR complex 2, focussed on one protomer Descriptor: ACETYL GROUP, DEP domain-containing mTOR-interacting protein, INOSITOL HEXAKISPHOSPHATE, ... Authors: Waelchli, M, Maier, T. Deposit date: 2021-08-09 Release date: 2021-09-08 Last modified: 2021-09-29 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Regulation of human mTOR complexes by DEPTOR. Elife, 10, 2021
7PEA	cryo-EM structure of DEPTOR bound to human mTOR complex 1, overall refinement Descriptor: DEP domain-containing mTOR-interacting protein, INOSITOL HEXAKISPHOSPHATE, Regulatory-associated protein of mTOR, ... Authors: Waelchli, M, Maier, T. Deposit date: 2021-08-09 Release date: 2021-09-08 Last modified: 2024-07-17 Method: ELECTRON MICROSCOPY (4.07 Å) Cite: Regulation of human mTOR complexes by DEPTOR. Elife, 10, 2021
6IG0	Type III-A Csm complex, Cryo-EM structure of Csm-CTR1, ATP bound Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CTR1, MAGNESIUM ION, ... Authors: You, L, Ma, J, Wang, J, Zhang, X, Wang, Y. Deposit date: 2018-09-21 Release date: 2018-12-12 Last modified: 2019-01-23 Method: ELECTRON MICROSCOPY (3.37 Å) Cite: Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference Cell, 176, 2019

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