5OGB

Human Cellular Retinoic Acid Binding Protein II (CRABPII) with bound synthetic retinoid DC360.

Summary for 5OGB

Entry DOI	10.2210/pdb5ogb/pdb
Descriptor	Cellular retinoic acid-binding protein 2, 4-[2-(4,4-dimethyl-1-propan-2-yl-quinolin-6-yl)ethynyl]benzoic acid (3 entities in total)
Functional Keywords	retinoid, fluorescent, dc360, crabpii, signaling protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	16058.43
Authors	Chisholm, D.,Tomlinson, C.,Whiting, A.,Pohl, E. (deposition date: 2017-07-12, release date: 2018-10-24, Last modification date: 2024-01-17)
Primary citation	Chisholm, D.R.,Tomlinson, C.W.E.,Zhou, G.L.,Holden, C.,Affleck, V.,Lamb, R.,Newling, K.,Ashton, P.,Valentine, R.,Redfern, C.,Erostyak, J.,Makkai, G.,Ambler, C.A.,Whiting, A.,Pohl, E. Fluorescent Retinoic Acid Analogues as Probes for Biochemical and Intracellular Characterization of Retinoid Signaling Pathways. Acs Chem.Biol., 14:369-377, 2019 Cited by PubMed: 30707838 DOI: 10.1021/acschembio.8b00916 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation