7PE8
cryo-EM structure of DEPTOR bound to human mTOR complex 2, focussed on one protomer
Summary for 7PE8
| Entry DOI | 10.2210/pdb7pe8/pdb |
| EMDB information | 13348 |
| Descriptor | Serine/threonine-protein kinase mTOR, Target of rapamycin complex subunit LST8, Rapamycin-insensitive companion of mTOR, ... (8 entities in total) |
| Functional Keywords | deptor, mtor, regulator, inhibitor, mtorc2, dep-domain, pdz-domain, signaling protein |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 5 |
| Total formula weight | 626047.02 |
| Authors | Waelchli, M.,Maier, T. (deposition date: 2021-08-09, release date: 2021-09-08, Last modification date: 2021-09-29) |
| Primary citation | Walchli, M.,Berneiser, K.,Mangia, F.,Imseng, S.,Craigie, L.M.,Stuttfeld, E.,Hall, M.N.,Maier, T. Regulation of human mTOR complexes by DEPTOR. Elife, 10:-, 2021 Cited by PubMed: 34519268DOI: 10.7554/eLife.70871 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.2 Å) |
Structure validation
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