6VLR
 
 | | BG505 SOSIP.v5.2 in complex with rhesus macaque Fab RM20E1 and PGT122 Fab | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIPv5.2 gp41, ... | | Authors: | Cottrell, C.A, Ward, A.B. | | Deposit date: | 2020-01-24 | | Release date: | 2020-06-24 | | Last modified: | 2020-09-16 | | Method: | ELECTRON MICROSCOPY (4.42 Å) | | Cite: | Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates.
Plos Pathog., 16, 2020
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6VK8
 | | Crystal Structure of Methylosinus trichosporium OB3b Soluble Methane Monooxygenase Hydroxylase and Regulatory Component Complex with small organic carboxylate at active center | | Descriptor: | 1,2-ETHANEDIOL, BENZOIC ACID, FE (III) ION, ... | | Authors: | Jones, J.C, Banerjee, R, Shi, K, Aihara, H, Lipscomb, J.D. | | Deposit date: | 2020-01-18 | | Release date: | 2020-08-05 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.03 Å) | | Cite: | Structural Studies of theMethylosinus trichosporiumOB3b Soluble Methane Monooxygenase Hydroxylase and Regulatory Component Complex Reveal a Transient Substrate Tunnel.
Biochemistry, 59, 2020
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7SPB
 | | Models for C13 reconstruction of Outer Membrane Core Complex (OMCC) of Type IV Secretion System (T4SS) encoded by F-plasmid (pED208). | | Descriptor: | TraB, TraK, TraV | | Authors: | Liu, X, Khara, P, Baker, M.L, Christie, P.J, Hu, B. | | Deposit date: | 2021-11-02 | | Release date: | 2022-02-02 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (3.31 Å) | | Cite: | Structure of a type IV secretion system core complex encoded by multi-drug resistance F plasmids
Nat Commun, 13, 2022
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7STZ
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6VLX
 | | Crystal structure of FabI from Alistipes finegoldii | | Descriptor: | Enoyl-[acyl-carrier-protein] reductase [NADH], GLYCEROL | | Authors: | Radka, C.D, Seetharaman, J, Rock, C.O. | | Deposit date: | 2020-01-27 | | Release date: | 2020-04-29 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.72 Å) | | Cite: | The genome of a Bacteroidetes inhabitant of the human gut encodes a structurally distinct enoyl-acyl carrier protein reductase (FabI).
J.Biol.Chem., 295, 2020
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7SPI
 | | Models for C13 reconstruction of Outer Membrane Core Complex (OMCC) of Type IV Secretion System (T4SS) encoded by a plasmid overproducing TraV, TraK and TraB of pED208 | | Descriptor: | TraB, TraK, TraV | | Authors: | Liu, X, Khara, P, Baker, M.L, Christie, P.J, Hu, B. | | Deposit date: | 2021-11-02 | | Release date: | 2022-02-02 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (2.97 Å) | | Cite: | Structure of a type IV secretion system core complex encoded by multi-drug resistance F plasmids
Nat Commun, 13, 2022
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7TEI
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6VMK
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7TF8
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7SSW
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6VRK
 | | Cryo-EM structure of the wild-type human serotonin transporter complexed with Br-paroxetine and 8B6 Fab | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 8B6 antibody, heavy chain, ... | | Authors: | Coleman, J.A, Navratna, V, Yang, D. | | Deposit date: | 2020-02-07 | | Release date: | 2020-03-11 | | Last modified: | 2020-09-23 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Chemical and structural investigation of the paroxetine-human serotonin transporter complex.
Elife, 9, 2020
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7SSN
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7SS9
 | | Late translocation intermediate with EF-G partially dissociated (Structure V) | | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | Authors: | Carbone, C.E, Loveland, A.B, Gamper, H.B, Hou, Y, Korostelev, A.A. | | Deposit date: | 2021-11-10 | | Release date: | 2022-02-23 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Time-resolved cryo-EM visualizes ribosomal translocation with EF-G and GTP.
Nat Commun, 12, 2021
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7ST6
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7ST7
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7ST2
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7SSL
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8BFL
 | | Jumbo Phage phi-kp24 empty capsid hexamers | | Descriptor: | Major head protein | | Authors: | Ouyang, R. | | Deposit date: | 2022-10-26 | | Release date: | 2022-12-07 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | High-resolution reconstruction of a Jumbo-bacteriophage infecting capsulated bacteria using hyperbranched tail fibers.
Nat Commun, 13, 2022
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7U2I
 | | Crystal structure of the Thermus thermophilus 70S ribosome in complex with mRNA, aminoacylated A-site Gly-NH-tRNAgly, aminoacylated P-site fMet-NH-tRNAmet, deacylated E-site tRNAgly, and chloramphenicol at 2.55A resolution | | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | | Authors: | Syroegin, E.A, Aleksandrova, E.V, Polikanov, Y.S. | | Deposit date: | 2022-02-24 | | Release date: | 2022-07-13 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Structural basis for the inability of chloramphenicol to inhibit peptide bond formation in the presence of A-site glycine.
Nucleic Acids Res., 50, 2022
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6VWN
 | | 70S ribosome bound to HIV frameshifting stem-loop (FSS) and P-site tRNA (non-rotated conformation, Structure II) | | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | Authors: | Loerch, S, Bao, C, Ling, C, Korostelev, A.A, Grigorieff, N, Ermolenko, D.M. | | Deposit date: | 2020-02-20 | | Release date: | 2020-06-03 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | mRNA stem-loops can pause the ribosome by hindering A-site tRNA binding.
Elife, 9, 2020
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7U2J
 | | Crystal structure of the Thermus thermophilus 70S ribosome in complex with mRNA, aminoacylated A-site Gly-NH-tRNAgly, peptidyl P-site fMAC-NH-tRNAmet, deacylated E-site tRNAgly, and chloramphenicol at 2.55A resolution | | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | | Authors: | Syroegin, E.A, Aleksandrova, E.V, Polikanov, Y.S. | | Deposit date: | 2022-02-24 | | Release date: | 2022-07-13 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Structural basis for the inability of chloramphenicol to inhibit peptide bond formation in the presence of A-site glycine.
Nucleic Acids Res., 50, 2022
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6VZ5
 | | Escherichia coli transcription-translation complex D3 (TTC-D3) containing mRNA with a 21 nt long spacer, NusG, and fMet-tRNAs at E-site and P-site | | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | | Authors: | Molodtsov, V, Wang, C, Su, M, Ebright, R.H. | | Deposit date: | 2020-02-27 | | Release date: | 2020-09-02 | | Last modified: | 2020-09-23 | | Method: | ELECTRON MICROSCOPY (8.9 Å) | | Cite: | Structural basis of transcription-translation coupling.
Science, 369, 2020
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6VU3
 | | Cryo-EM structure of Escherichia coli transcription-translation complex A (TTC-A) containing mRNA with a 12 nt long spacer | | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | | Authors: | Molodtsov, V, Wang, C, Su, M, Ebright, R. | | Deposit date: | 2020-02-14 | | Release date: | 2020-09-02 | | Last modified: | 2020-09-23 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Structural basis of transcription-translation coupling.
Science, 369, 2020
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7TSK
 | | Structure of human endothelial nitric oxide synthase heme domain in complex with 4-methyl-6-(3-(methylamino)prop-1-yn-1-yl)pyridin-2-amine | | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-methyl-6-[3-(methylamino)prop-1-yn-1-yl]pyridin-2-amine, 5,6,7,8-TETRAHYDROBIOPTERIN, ... | | Authors: | Li, H, Poulos, T.L. | | Deposit date: | 2022-01-31 | | Release date: | 2022-07-13 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.049 Å) | | Cite: | 2-Aminopyridines with a shortened amino sidechain as potent, selective, and highly permeable human neuronal nitric oxide synthase inhibitors.
Bioorg.Med.Chem., 69, 2022
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8BSD
 | | SARS-CoV-2 nsp10-16 methyltransferase in complex with tubercidin | | Descriptor: | '2-(4-AMINO-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL, 1,2-ETHANEDIOL, 2'-O-methyltransferase nsp16, ... | | Authors: | Kremling, V, Oberthuer, D, Sprenger, J. | | Deposit date: | 2022-11-24 | | Release date: | 2022-12-07 | | Last modified: | 2024-06-19 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Crystal structures of Tubercidin bound to the active site of the SARS-CoV-2 methyltransferase nsp10-16
To Be Published
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