8BSD

SARS-CoV-2 nsp10-16 methyltransferase in complex with tubercidin

Summary for 8BSD

• Entry DOI: 10.2210/pdb8bsd/pdb
• Descriptor: 2'-O-methyltransferase nsp16, Non-structural protein 10, 1,2-ETHANEDIOL, ... (8 entities in total)
• Functional Keywords: methyltransferase, complex, inhibitor, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2; More
• Total number of polymer chains: 2
• Total formula weight: 51597.39

Authors

Kremling, V.,Oberthuer, D.,Sprenger, J. (deposition date: 2022-11-24, release date: 2022-12-07, Last modification date: 2024-11-13)

• Primary citation: Kremling, V.,Falke, S.,Fernandez-Garcia, Y.,Ehrt, C.,Kiene, A.,Klopprogge, B.,Scheer, E.,Barthels, F.,Middendorf, P.,Kuhn, S.,Gunther, S.,Rarey, M.,Chapman, H.N.,Oberthur, D.,Sprenger, J.; SARS-CoV-2 methyltransferase nsp10-16 in complex with natural and drug-like purine analogs for guiding structure-based drug discovery; Elife, 2024; DOI: 10.7554/elife.98310.1

Experimental method

X-RAY DIFFRACTION (1.95 Å)