6VMK
Crystal structure of human Complement Factor D with anti-Factor D Fab 20D12
Summary for 6VMK
Entry DOI | 10.2210/pdb6vmk/pdb |
Descriptor | Complement factor D, Fab Y49R light chain, Fab Y49R heavy chain, ... (6 entities in total) |
Functional Keywords | cfd, factor d, fab, hydrolase, hydrolase-immune system complex, hydrolase/immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 48 |
Total formula weight | 1146018.37 |
Authors | Wu, P.,Harris, S.F.,Eigenbrot, C. (deposition date: 2020-01-28, release date: 2021-02-03, Last modification date: 2024-04-03) |
Primary citation | Dion, M.,Wu, P.,Morando, A.,Bullen, G.,Shatz, W.,Harris, S.F.,Eigenbrot, C.,Loyet, K.M.,Yadav, D.,Tassew, N.,Booler, H.,Scheer, J.,Kelley, R.F.,Tesar, D.B. Crystal structure of human Complement Factor D with anti-Factor D Fab 20D12 To Be Published, |
Experimental method | X-RAY DIFFRACTION (3.01 Å) |
Structure validation
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