8S5H
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8S5K
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8S5J
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8S5L
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8S5M
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1AM4
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![BU of 1am4 by Molmil](/molmil-images/mine/1am4) | COMPLEX BETWEEN CDC42HS.GMPPNP AND P50 RHOGAP (H. SAPIENS) | Descriptor: | CDC42HS, MAGNESIUM ION, P50-RHOGAP, ... | Authors: | Rittinger, K, Walker, P, Gamblin, S.J, Smerdon, S.J. | Deposit date: | 1997-06-22 | Release date: | 1998-07-15 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of a small G protein in complex with the GTPase-activating protein rhoGAP. Nature, 388, 1997
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8TO0
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![BU of 8to0 by Molmil](/molmil-images/mine/8to0) | 48-nm repeating structure of doublets from mouse sperm flagella | Descriptor: | Cilia- and flagella- associated protein 210, Cilia- and flagella-associated protein 107, Cilia- and flagella-associated protein 141, ... | Authors: | Chen, Z, Shiozak, M, Hass, K.M, Skinner, W, Zhao, S, Guo, C, Polacco, B.J, Yu, Z, Krogan, N.J, Kaake, R.M, Vale, R.D, Agard, D.A. | Deposit date: | 2023-08-02 | Release date: | 2023-11-01 | Last modified: | 2023-11-22 | Method: | ELECTRON MICROSCOPY (7.7 Å) | Cite: | De novo protein identification in mammalian sperm using in situ cryoelectron tomography and AlphaFold2 docking. Cell, 186, 2023
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1A4R
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![BU of 1a4r by Molmil](/molmil-images/mine/1a4r) | G12V MUTANT OF HUMAN PLACENTAL CDC42 GTPASE IN THE GDP FORM | Descriptor: | AMINOPHOSPHONIC ACID-GUANYLATE ESTER, G25K GTP-BINDING PROTEIN, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Rudolph, M.G, Vetter, I.R, Wittinghofer, A. | Deposit date: | 1998-02-02 | Release date: | 1999-03-02 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Nucleotide binding to the G12V-mutant of Cdc42 investigated by X-ray diffraction and fluorescence spectroscopy: two different nucleotide states in one crystal. Protein Sci., 8, 1999
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4CR2
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![BU of 4cr2 by Molmil](/molmil-images/mine/4cr2) | Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S proteasome | Descriptor: | 26S PROTEASE REGULATORY SUBUNIT 4 HOMOLOG, 26S PROTEASE REGULATORY SUBUNIT 6A, 26S PROTEASE REGULATORY SUBUNIT 6B HOMOLOG, ... | Authors: | Unverdorben, P, Beck, F, Sledz, P, Schweitzer, A, Pfeifer, G, Plitzko, J.M, Baumeister, W, Foerster, F. | Deposit date: | 2014-02-25 | Release date: | 2014-04-02 | Last modified: | 2018-10-03 | Method: | ELECTRON MICROSCOPY (7.7 Å) | Cite: | Deep Classification of a Large Cryo-Em Dataset Defines the Conformational Landscape of the 26S Proteasome. Proc.Natl.Acad.Sci.USA, 111, 2014
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4CR4
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![BU of 4cr4 by Molmil](/molmil-images/mine/4cr4) | Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S proteasome | Descriptor: | 26S PROTEASE REGULATORY SUBUNIT 4 HOMOLOG, 26S PROTEASE REGULATORY SUBUNIT 6A, 26S PROTEASE REGULATORY SUBUNIT 6B HOMOLOG, ... | Authors: | Unverdorben, P, Beck, F, Sledz, P, Schweitzer, A, Pfeifer, G, Plitzko, J.M, Baumeister, W, Foerster, F. | Deposit date: | 2014-02-25 | Release date: | 2014-04-02 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (8.8 Å) | Cite: | Deep Classification of a Large Cryo-Em Dataset Defines the Conformational Landscape of the 26S Proteasome. Proc.Natl.Acad.Sci.USA, 111, 2014
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4CR3
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![BU of 4cr3 by Molmil](/molmil-images/mine/4cr3) | Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S proteasome | Descriptor: | 26S PROTEASE REGULATORY SUBUNIT 4 HOMOLOG, 26S PROTEASE REGULATORY SUBUNIT 6A, 26S PROTEASE REGULATORY SUBUNIT 6B HOMOLOG, ... | Authors: | Unverdorben, P, Beck, F, Sledz, P, Schweitzer, A, Pfeifer, G, Plitzko, J.M, Baumeister, W, Foerster, F. | Deposit date: | 2014-02-25 | Release date: | 2014-04-02 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (9.3 Å) | Cite: | Deep Classification of a Large Cryo-Em Dataset Defines the Conformational Landscape of the 26S Proteasome. Proc.Natl.Acad.Sci.USA, 111, 2014
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1AJE
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![BU of 1aje by Molmil](/molmil-images/mine/1aje) | CDC42 FROM HUMAN, NMR, 20 STRUCTURES | Descriptor: | CDC42HS | Authors: | Feltham, J.L, Dotsch, V, Raza, S, Manor, D, Cerione, R.A, Sutcliffe, M.J, Wagner, G, Oswald, R.E. | Deposit date: | 1997-05-02 | Release date: | 1997-11-12 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Definition of the switch surface in the solution structure of Cdc42Hs. Biochemistry, 36, 1997
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1AN0
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![BU of 1an0 by Molmil](/molmil-images/mine/1an0) | CDC42HS-GDP COMPLEX | Descriptor: | CDC42HS-GDP, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | Authors: | Kongsaeree, P, Cerione, R, Clardy, J. | Deposit date: | 1997-06-26 | Release date: | 1999-01-13 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The Structure Determination of Cdc42Hs and Gdp Complex To be Published
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4COO
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![BU of 4coo by Molmil](/molmil-images/mine/4coo) | Crystal structure of human cystathionine beta-synthase (delta516-525) at 2.0 angstrom resolution | Descriptor: | 1,2-ETHANEDIOL, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ACETATE ION, ... | Authors: | McCorvie, T.J, Kopec, J, Vollamar, M, Strain-Damerell, C, Bushell, S, Bradley, A, Tallant, C, Kiyani, W, Froese, D.S, Carpenter, E.S, Burgess-Brown, N, von Delft, F, Arrowsmith, C, Edwards, A, Bountra, C, Yue, W.W. | Deposit date: | 2014-01-29 | Release date: | 2014-03-05 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Inter-Domain Communication of Human Cystathionine Beta Synthase: Structural Basis of S-Adenosyl-L-Methionine Activation. J.Biol.Chem., 289, 2014
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4DID
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6J30
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![BU of 6j30 by Molmil](/molmil-images/mine/6j30) | yeast proteasome in Ub-engaged state (C2) | Descriptor: | 26S proteasome complex subunit SEM1, 26S proteasome regulatory subunit 4 homolog, 26S proteasome regulatory subunit 6A, ... | Authors: | Cong, Y. | Deposit date: | 2019-01-03 | Release date: | 2019-03-20 | Last modified: | 2019-11-06 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Structural Snapshots of 26S Proteasome Reveal Tetraubiquitin-Induced Conformations. Mol. Cell, 73, 2019
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6J2N
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![BU of 6j2n by Molmil](/molmil-images/mine/6j2n) | yeast proteasome in substrate-processing state (C3-b) | Descriptor: | 26S protease regulatory subunit 4 homolog, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B homolog, ... | Authors: | Cong, Y. | Deposit date: | 2019-01-02 | Release date: | 2019-03-20 | Last modified: | 2019-11-06 | Method: | ELECTRON MICROSCOPY (7.5 Å) | Cite: | Structural Snapshots of 26S Proteasome Reveal Tetraubiquitin-Induced Conformations. Mol. Cell, 73, 2019
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6J2C
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![BU of 6j2c by Molmil](/molmil-images/mine/6j2c) | Yeast proteasome in translocation competent state (C3-a) | Descriptor: | 26S protease regulatory subunit 4 homolog, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B homolog, ... | Authors: | Cong, Y. | Deposit date: | 2019-01-01 | Release date: | 2019-03-13 | Last modified: | 2019-11-06 | Method: | ELECTRON MICROSCOPY (7 Å) | Cite: | Structural Snapshots of 26S Proteasome Reveal Tetraubiquitin-Induced Conformations. Mol. Cell, 73, 2019
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6J2X
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![BU of 6j2x by Molmil](/molmil-images/mine/6j2x) | Yeast proteasome in resting state (C1-a) | Descriptor: | 26S PROTEASE REGULATORY SUBUNIT 4 HOMOLOG, 26S PROTEASOME REGULATORY SUBUNIT RPN5, 26S proteasome complex subunit SEM1, ... | Authors: | Cong, Y. | Deposit date: | 2019-01-03 | Release date: | 2019-03-13 | Last modified: | 2019-11-06 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structural Snapshots of 26S Proteasome Reveal Tetraubiquitin-Induced Conformations. Mol. Cell, 73, 2019
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6J2Q
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![BU of 6j2q by Molmil](/molmil-images/mine/6j2q) | Yeast proteasome in Ub-accepted state (C1-b) | Descriptor: | 26S protease regulatory subunit 4 homolog, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B homolog, ... | Authors: | Cong, Y. | Deposit date: | 2019-01-02 | Release date: | 2019-03-13 | Last modified: | 2019-04-10 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structural Snapshots of 26S Proteasome Reveal Tetraubiquitin-Induced Conformations. Mol. Cell, 73, 2019
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6N8O
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![BU of 6n8o by Molmil](/molmil-images/mine/6n8o) | Cryo-EM structure of Rpl10-inserted (RI) pre-60S ribosomal subunit | Descriptor: | 5.8S rRNA, 5S rRNA, 60S ribosomal export protein NMD3, ... | Authors: | Zhou, Y, Musalgaonkar, S, Johnson, A.W, Taylor, D.W. | Deposit date: | 2018-11-29 | Release date: | 2019-03-13 | Last modified: | 2020-01-08 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome. Nat Commun, 10, 2019
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6N8N
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![BU of 6n8n by Molmil](/molmil-images/mine/6n8n) | Cryo-EM structure of Lsg1-engaged (LE) pre-60S ribosomal subunit | Descriptor: | 5.8S rRNA, 5S rRNA, 60S ribosomal export protein NMD3, ... | Authors: | Zhou, Y, Musalgaonkar, S, Johnson, A.W, Taylor, D.W. | Deposit date: | 2018-11-29 | Release date: | 2019-03-13 | Last modified: | 2020-01-08 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome. Nat Commun, 10, 2019
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6XIQ
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![BU of 6xiq by Molmil](/molmil-images/mine/6xiq) | Cryo-EM Structure of K63R Ubiquitin Mutant Ribosome under Oxidative Stress | Descriptor: | 18S ribosomal RNA, 35S ribosomal RNA, 40S ribosomal protein S0-A, ... | Authors: | Zhou, Y, Bartesaghi, A, Silva, G.M. | Deposit date: | 2020-06-21 | Release date: | 2020-08-26 | Last modified: | 2020-09-23 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structural impact of K63 ubiquitin on yeast translocating ribosomes under oxidative stress. Proc.Natl.Acad.Sci.USA, 117, 2020
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6N8M
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![BU of 6n8m by Molmil](/molmil-images/mine/6n8m) | Cryo-EM structure of pre-Lsg1 (PL) pre-60S ribosomal subunit | Descriptor: | 5.8S RNA, 5S rRNA, 60S ribosomal export protein NMD3, ... | Authors: | Zhou, Y, Musalgaonkar, S, Johnson, A.W, Taylor, D.W. | Deposit date: | 2018-11-29 | Release date: | 2019-03-13 | Last modified: | 2020-01-08 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome. Nat Commun, 10, 2019
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3QBV
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![BU of 3qbv by Molmil](/molmil-images/mine/3qbv) | Structure of designed orthogonal interaction between CDC42 and nucleotide exchange domains of intersectin | Descriptor: | Cell division control protein 42 homolog, GUANOSINE-5'-DIPHOSPHATE, Intersectin-1 | Authors: | Kapp, G.T, Remenyi, A, Lim, W.A, Kortemme, T. | Deposit date: | 2011-01-14 | Release date: | 2012-02-08 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Control of protein signaling using a computationally designed GTPase/GEF orthogonal pair. Proc.Natl.Acad.Sci.USA, 109, 2012
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