8S5H
 
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8S5K
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8S5J
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8S5L
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8S5M
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1AM4
 | | COMPLEX BETWEEN CDC42HS.GMPPNP AND P50 RHOGAP (H. SAPIENS) | | Descriptor: | CDC42HS, MAGNESIUM ION, P50-RHOGAP, ... | | Authors: | Rittinger, K, Walker, P, Gamblin, S.J, Smerdon, S.J. | | Deposit date: | 1997-06-22 | | Release date: | 1998-07-15 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal structure of a small G protein in complex with the GTPase-activating protein rhoGAP.
Nature, 388, 1997
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8TO0
 | | 48-nm repeating structure of doublets from mouse sperm flagella | | Descriptor: | Cilia- and flagella- associated protein 210, Cilia- and flagella-associated protein 107, Cilia- and flagella-associated protein 141, ... | | Authors: | Chen, Z, Shiozak, M, Hass, K.M, Skinner, W, Zhao, S, Guo, C, Polacco, B.J, Yu, Z, Krogan, N.J, Kaake, R.M, Vale, R.D, Agard, D.A. | | Deposit date: | 2023-08-02 | | Release date: | 2023-11-01 | | Last modified: | 2023-11-22 | | Method: | ELECTRON MICROSCOPY (7.7 Å) | | Cite: | De novo protein identification in mammalian sperm using in situ cryoelectron tomography and AlphaFold2 docking.
Cell, 186, 2023
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1A4R
 | | G12V MUTANT OF HUMAN PLACENTAL CDC42 GTPASE IN THE GDP FORM | | Descriptor: | AMINOPHOSPHONIC ACID-GUANYLATE ESTER, G25K GTP-BINDING PROTEIN, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Rudolph, M.G, Vetter, I.R, Wittinghofer, A. | | Deposit date: | 1998-02-02 | | Release date: | 1999-03-02 | | Last modified: | 2023-08-02 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Nucleotide binding to the G12V-mutant of Cdc42 investigated by X-ray diffraction and fluorescence spectroscopy: two different nucleotide states in one crystal.
Protein Sci., 8, 1999
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4CR2
 | | Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S proteasome | | Descriptor: | 26S PROTEASE REGULATORY SUBUNIT 4 HOMOLOG, 26S PROTEASE REGULATORY SUBUNIT 6A, 26S PROTEASE REGULATORY SUBUNIT 6B HOMOLOG, ... | | Authors: | Unverdorben, P, Beck, F, Sledz, P, Schweitzer, A, Pfeifer, G, Plitzko, J.M, Baumeister, W, Foerster, F. | | Deposit date: | 2014-02-25 | | Release date: | 2014-04-02 | | Last modified: | 2018-10-03 | | Method: | ELECTRON MICROSCOPY (7.7 Å) | | Cite: | Deep Classification of a Large Cryo-Em Dataset Defines the Conformational Landscape of the 26S Proteasome.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4CR4
 | | Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S proteasome | | Descriptor: | 26S PROTEASE REGULATORY SUBUNIT 4 HOMOLOG, 26S PROTEASE REGULATORY SUBUNIT 6A, 26S PROTEASE REGULATORY SUBUNIT 6B HOMOLOG, ... | | Authors: | Unverdorben, P, Beck, F, Sledz, P, Schweitzer, A, Pfeifer, G, Plitzko, J.M, Baumeister, W, Foerster, F. | | Deposit date: | 2014-02-25 | | Release date: | 2014-04-02 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (8.8 Å) | | Cite: | Deep Classification of a Large Cryo-Em Dataset Defines the Conformational Landscape of the 26S Proteasome.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4CR3
 | | Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S proteasome | | Descriptor: | 26S PROTEASE REGULATORY SUBUNIT 4 HOMOLOG, 26S PROTEASE REGULATORY SUBUNIT 6A, 26S PROTEASE REGULATORY SUBUNIT 6B HOMOLOG, ... | | Authors: | Unverdorben, P, Beck, F, Sledz, P, Schweitzer, A, Pfeifer, G, Plitzko, J.M, Baumeister, W, Foerster, F. | | Deposit date: | 2014-02-25 | | Release date: | 2014-04-02 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (9.3 Å) | | Cite: | Deep Classification of a Large Cryo-Em Dataset Defines the Conformational Landscape of the 26S Proteasome.
Proc.Natl.Acad.Sci.USA, 111, 2014
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1AJE
 | | CDC42 FROM HUMAN, NMR, 20 STRUCTURES | | Descriptor: | CDC42HS | | Authors: | Feltham, J.L, Dotsch, V, Raza, S, Manor, D, Cerione, R.A, Sutcliffe, M.J, Wagner, G, Oswald, R.E. | | Deposit date: | 1997-05-02 | | Release date: | 1997-11-12 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Definition of the switch surface in the solution structure of Cdc42Hs.
Biochemistry, 36, 1997
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1AN0
 | | CDC42HS-GDP COMPLEX | | Descriptor: | CDC42HS-GDP, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | | Authors: | Kongsaeree, P, Cerione, R, Clardy, J. | | Deposit date: | 1997-06-26 | | Release date: | 1999-01-13 | | Last modified: | 2021-11-03 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | The Structure Determination of Cdc42Hs and Gdp Complex
To be Published
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4COO
 | | Crystal structure of human cystathionine beta-synthase (delta516-525) at 2.0 angstrom resolution | | Descriptor: | 1,2-ETHANEDIOL, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ACETATE ION, ... | | Authors: | McCorvie, T.J, Kopec, J, Vollamar, M, Strain-Damerell, C, Bushell, S, Bradley, A, Tallant, C, Kiyani, W, Froese, D.S, Carpenter, E.S, Burgess-Brown, N, von Delft, F, Arrowsmith, C, Edwards, A, Bountra, C, Yue, W.W. | | Deposit date: | 2014-01-29 | | Release date: | 2014-03-05 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Inter-Domain Communication of Human Cystathionine Beta Synthase: Structural Basis of S-Adenosyl-L-Methionine Activation.
J.Biol.Chem., 289, 2014
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4DID
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6J30
 | | yeast proteasome in Ub-engaged state (C2) | | Descriptor: | 26S proteasome complex subunit SEM1, 26S proteasome regulatory subunit 4 homolog, 26S proteasome regulatory subunit 6A, ... | | Authors: | Cong, Y. | | Deposit date: | 2019-01-03 | | Release date: | 2019-03-20 | | Last modified: | 2019-11-06 | | Method: | ELECTRON MICROSCOPY (4.5 Å) | | Cite: | Structural Snapshots of 26S Proteasome Reveal Tetraubiquitin-Induced Conformations.
Mol. Cell, 73, 2019
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6J2N
 | | yeast proteasome in substrate-processing state (C3-b) | | Descriptor: | 26S protease regulatory subunit 4 homolog, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B homolog, ... | | Authors: | Cong, Y. | | Deposit date: | 2019-01-02 | | Release date: | 2019-03-20 | | Last modified: | 2019-11-06 | | Method: | ELECTRON MICROSCOPY (7.5 Å) | | Cite: | Structural Snapshots of 26S Proteasome Reveal Tetraubiquitin-Induced Conformations.
Mol. Cell, 73, 2019
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6J2C
 | | Yeast proteasome in translocation competent state (C3-a) | | Descriptor: | 26S protease regulatory subunit 4 homolog, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B homolog, ... | | Authors: | Cong, Y. | | Deposit date: | 2019-01-01 | | Release date: | 2019-03-13 | | Last modified: | 2019-11-06 | | Method: | ELECTRON MICROSCOPY (7 Å) | | Cite: | Structural Snapshots of 26S Proteasome Reveal Tetraubiquitin-Induced Conformations.
Mol. Cell, 73, 2019
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6J2X
 | | Yeast proteasome in resting state (C1-a) | | Descriptor: | 26S PROTEASE REGULATORY SUBUNIT 4 HOMOLOG, 26S PROTEASOME REGULATORY SUBUNIT RPN5, 26S proteasome complex subunit SEM1, ... | | Authors: | Cong, Y. | | Deposit date: | 2019-01-03 | | Release date: | 2019-03-13 | | Last modified: | 2019-11-06 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Structural Snapshots of 26S Proteasome Reveal Tetraubiquitin-Induced Conformations.
Mol. Cell, 73, 2019
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6J2Q
 | | Yeast proteasome in Ub-accepted state (C1-b) | | Descriptor: | 26S protease regulatory subunit 4 homolog, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B homolog, ... | | Authors: | Cong, Y. | | Deposit date: | 2019-01-02 | | Release date: | 2019-03-13 | | Last modified: | 2019-04-10 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Structural Snapshots of 26S Proteasome Reveal Tetraubiquitin-Induced Conformations.
Mol. Cell, 73, 2019
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6N8O
 | | Cryo-EM structure of Rpl10-inserted (RI) pre-60S ribosomal subunit | | Descriptor: | 5.8S rRNA, 5S rRNA, 60S ribosomal export protein NMD3, ... | | Authors: | Zhou, Y, Musalgaonkar, S, Johnson, A.W, Taylor, D.W. | | Deposit date: | 2018-11-29 | | Release date: | 2019-03-13 | | Last modified: | 2020-01-08 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome.
Nat Commun, 10, 2019
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6N8N
 | | Cryo-EM structure of Lsg1-engaged (LE) pre-60S ribosomal subunit | | Descriptor: | 5.8S rRNA, 5S rRNA, 60S ribosomal export protein NMD3, ... | | Authors: | Zhou, Y, Musalgaonkar, S, Johnson, A.W, Taylor, D.W. | | Deposit date: | 2018-11-29 | | Release date: | 2019-03-13 | | Last modified: | 2020-01-08 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome.
Nat Commun, 10, 2019
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6XIQ
 | | Cryo-EM Structure of K63R Ubiquitin Mutant Ribosome under Oxidative Stress | | Descriptor: | 18S ribosomal RNA, 35S ribosomal RNA, 40S ribosomal protein S0-A, ... | | Authors: | Zhou, Y, Bartesaghi, A, Silva, G.M. | | Deposit date: | 2020-06-21 | | Release date: | 2020-08-26 | | Last modified: | 2020-09-23 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Structural impact of K63 ubiquitin on yeast translocating ribosomes under oxidative stress.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6N8M
 | | Cryo-EM structure of pre-Lsg1 (PL) pre-60S ribosomal subunit | | Descriptor: | 5.8S RNA, 5S rRNA, 60S ribosomal export protein NMD3, ... | | Authors: | Zhou, Y, Musalgaonkar, S, Johnson, A.W, Taylor, D.W. | | Deposit date: | 2018-11-29 | | Release date: | 2019-03-13 | | Last modified: | 2020-01-08 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome.
Nat Commun, 10, 2019
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3QBV
 | | Structure of designed orthogonal interaction between CDC42 and nucleotide exchange domains of intersectin | | Descriptor: | Cell division control protein 42 homolog, GUANOSINE-5'-DIPHOSPHATE, Intersectin-1 | | Authors: | Kapp, G.T, Remenyi, A, Lim, W.A, Kortemme, T. | | Deposit date: | 2011-01-14 | | Release date: | 2012-02-08 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Control of protein signaling using a computationally designed GTPase/GEF orthogonal pair.
Proc.Natl.Acad.Sci.USA, 109, 2012
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