PDB: 294 resultsInfo pagesStatus searchChemie searchBIRD

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3UL0	Mouse importin alpha: mouse CBP80Y8D cNLS complex Descriptor: Importin subunit alpha-2, Nuclear cap-binding protein subunit 1 Authors: Marfori, M, Forwood, J.K, Lonhienne, T.G, Kobe, B. Deposit date: 2011-11-10 Release date: 2012-10-03 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural Basis of High-Affinity Nuclear Localization Signal Interactions with Importin-alpha Traffic, 13, 2012
4R10	A conserved phosphorylation switch controls the interaction between cadherin and beta-catenin in vitro and in vivo Descriptor: 1,2-ETHANEDIOL, Cadherin-related hmr-1, Protein humpback-2, ... Authors: Choi, H.-J, Loveless, T, Lynch, A, Bang, I, Hardin, J, Weis, W.I. Deposit date: 2014-08-03 Release date: 2015-04-29 Method: X-RAY DIFFRACTION (2.3 Å) Cite: A Conserved Phosphorylation Switch Controls the Interaction between Cadherin and beta-Catenin In Vitro and In Vivo Dev.Cell, 33, 2015
4RXH	Crystal Structure of Importin-alpha from Neurospora crassa complexed with SV40NLS Descriptor: Importin subunit alpha, Large T antigen Authors: Bernardes, N.E, Takeda, A.A.S, Fontes, M.R.M. Deposit date: 2014-12-11 Release date: 2015-07-01 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.7553 Å) Cite: Structure of Importin-alpha from a Filamentous Fungus in Complex with a Classical Nuclear Localization Signal. Plos One, 10, 2015
3RZ9	Mouse importin alpha-Ku80 NLS peptide complex Descriptor: Importin subunit alpha-2, Ku80 NLS peptide Authors: Barros, A.C, Takeda, A.A.S, Fontes, M.R.M. Deposit date: 2011-05-11 Release date: 2011-08-03 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.29 Å) Cite: Structural basis of importin-alpha-mediated nuclear transport for Ku70 and Ku80. J.Mol.Biol., 412, 2011
4TNM	Crystal structure of Arabidopsis importin-alpha3 armadillo repeat domain Descriptor: Importin subunit alpha Authors: Wirthmueller, L, Banfield, M. Deposit date: 2014-06-04 Release date: 2014-10-08 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Probing formation of cargo/importin-alpha transport complexes in plant cells using a pathogen effector. Plant J., 81, 2015
3T7U	A NeW Crystal structure of APC-ARM Descriptor: Adenomatous polyposis coli protein, PHOSPHATE ION Authors: Zhang, Z, Wu, G. Deposit date: 2011-07-31 Release date: 2011-12-14 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Crystal structure of the armadillo repeat domain of adenomatous polyposis coli which reveals its inherent flexibility Biochem.Biophys.Res.Commun., 412, 2011
4UAF	Importin alpha 1 delta IBB in complex with Influenza PB2 nuclear localization domain Descriptor: Importin subunit alpha-1, PHOSPHATE ION, Polymerase basic protein 2 Authors: Pumroy, R.A, Cingolani, G. Deposit date: 2014-08-08 Release date: 2015-02-04 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (1.698 Å) Cite: Molecular Determinants for Nuclear Import of Influenza A PB2 by Importin alpha Isoforms 3 and 7. Structure, 23, 2015
3UVU	Structural basis of nuclear import of Flap endonuclease 1 (FEN1) Descriptor: Flap endonuclease 1 (Fen1) peptide, Importin subunit alpha-2 Authors: Barros, A.C, Takeda, A.A.S, Fontes, M.R.M. Deposit date: 2011-11-30 Release date: 2012-06-27 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.38 Å) Cite: Structural basis of nuclear import of flap endonuclease 1 (FEN1). Acta Crystallogr.,Sect.D, 68, 2012
4U2X	Ebola virus VP24 in complex with Karyopherin alpha 5 C-terminus Descriptor: CHLORIDE ION, Importin subunit alpha-6, Membrane-associated protein VP24 Authors: Xu, W, Leung, D, Borek, D, Amarasinghe, G. Deposit date: 2014-07-18 Release date: 2014-08-13 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (3.153 Å) Cite: Ebola Virus VP24 Targets a Unique NLS Binding Site on Karyopherin Alpha 5 to Selectively Compete with Nuclear Import of Phosphorylated STAT1. Cell Host Microbe, 16, 2014
4U5L	IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR Descriptor: Importin subunit alpha-1, N~2~-[4-(pyridin-3-yl)benzyl]-L-lysinamide Authors: Stewart, M, Valkov, E, Holvey, R.S. Deposit date: 2014-07-25 Release date: 2015-05-13 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.53 Å) Cite: Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design. Chemmedchem, 10, 2015
4U5V	IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR Descriptor: Importin subunit alpha-1, N~2~-{[5-(pyridin-3-yl)thiophen-2-yl]methyl}-L-lysinamide Authors: Stewart, M, Valkov, E, Holvey, R.S. Deposit date: 2014-07-25 Release date: 2015-05-13 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.968 Å) Cite: Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design. Chemmedchem, 10, 2015
4U54	IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR Descriptor: Importin subunit alpha-1, N-methyl-1-[3-(pyridin-3-yl)phenyl]methanamine Authors: Stewart, M, Valkov, E, Holvey, R.S. Deposit date: 2014-07-24 Release date: 2015-05-13 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.41 Å) Cite: Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design. Chemmedchem, 10, 2015
4U5U	IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR Descriptor: Importin subunit alpha-1, N~2~-[3-(pyridin-3-yl)benzyl]-L-lysinamide Authors: Stewart, M, Valkov, E, Holvey, R.S. Deposit date: 2014-07-25 Release date: 2015-05-13 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.96 Å) Cite: Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design. Chemmedchem, 10, 2015
4U5N	IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR Descriptor: Importin subunit alpha-1, N~2~-[4-(pyridin-3-yl)benzyl]-L-lysyl-N-[(1R,2S,3R)-1-{[(2R)-1-amino-1-oxo-3-phenylpropan-2-yl]amino}-1,3-dihydroxybutan-2-yl]glycinamide Authors: Stewart, M, Valkov, E, Holvey, R.S. Deposit date: 2014-07-25 Release date: 2015-05-13 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.31 Å) Cite: Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design. Chemmedchem, 10, 2015
4U5S	IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR Descriptor: Importin subunit alpha-1, N-[(2S)-2-[(N~2~-acetyl-D-lysyl)amino]-3-(pyridin-3-ylmethoxy)propyl]-L-allothreonyl-D-phenylalaninamide Authors: Stewart, M, Valkov, E, Holvey, R.S. Deposit date: 2014-07-25 Release date: 2015-05-13 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.12 Å) Cite: Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design. Chemmedchem, 10, 2015
4UAE	Importin alpha 3 delta IBB in complex with Influenza PB2 Nuclear Localization Domain Descriptor: Importin subunit alpha-3, Polymerase basic protein 2, SULFATE ION Authors: Pumroy, R.A, Cingolani, G. Deposit date: 2014-08-08 Release date: 2015-02-04 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Molecular Determinants for Nuclear Import of Influenza A PB2 by Importin alpha Isoforms 3 and 7. Structure, 23, 2015
4U58	IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR Descriptor: Importin subunit alpha-1, N~2~-[4-(pyridin-3-yl)benzoyl]-L-lysinamide Authors: Stewart, M, Valkov, E, Holvey, R.S. Deposit date: 2014-07-24 Release date: 2015-05-13 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.56 Å) Cite: Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design. Chemmedchem, 10, 2015
4U5O	IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR Descriptor: Importin subunit alpha-1, N~2~-[4-(pyridin-3-yl)benzyl]-D-lysinamide Authors: Stewart, M, Valkov, E, Holvey, R.S. Deposit date: 2014-07-25 Release date: 2015-05-13 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2 Å) Cite: Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design. Chemmedchem, 10, 2015
4UAD	Importin alpha 7 delta IBB in complex with Influenza PB2 Nuclear Localization Domain Descriptor: Importin subunit alpha-7, Polymerase basic protein 2 Authors: Pumroy, R.A, Cingolani, G. Deposit date: 2014-08-08 Release date: 2015-02-04 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.42 Å) Cite: Molecular Determinants for Nuclear Import of Influenza A PB2 by Importin alpha Isoforms 3 and 7. Structure, 23, 2015
3UL1	Mouse importin alpha: nucleoplasmin cNLS peptide complex Descriptor: Importin subunit alpha-2, Nucleoplasmin Authors: Marfori, M, Forwood, J.K, Lonhienne, T.G, Kobe, B. Deposit date: 2011-11-10 Release date: 2012-10-03 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural Basis of High-Affinity Nuclear Localization Signal Interactions with Importin-alpha Traffic, 13, 2012
3UKY	Mouse importin alpha: yeast CBP80 cNLS complex Descriptor: Importin subunit alpha-2, Nuclear cap-binding protein complex subunit 1 Authors: Marfori, M, Forwood, J.K, Lonhienne, T.G, Kobe, B. Deposit date: 2011-11-10 Release date: 2012-10-03 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Structural Basis of High-Affinity Nuclear Localization Signal Interactions with Importin-alpha Traffic, 13, 2012
3VE6	Crystal Structure Analysis of Venezuelan Equine Encephalitis Virus Capsid Protein NLS and Importin Alpha Descriptor: Importin subunit alpha-2, Venezuelan equine encephalitis virus capsid protein NLS Authors: Fan, F. Deposit date: 2012-01-07 Release date: 2012-01-25 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.829 Å) Cite: Crystal Structure Analysis of Venezuelan Equine Encephalitis Virus Capsid Protein NLS and Importin Alpha To be Published
3UKW	Mouse importin alpha: Bimax1 peptide complex Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Bimax1 peptide, Importin subunit alpha-2 Authors: Marfori, M, Forwood, J.K, Lonhienne, T.G, Kobe, B. Deposit date: 2011-11-10 Release date: 2012-10-03 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural Basis of High-Affinity Nuclear Localization Signal Interactions with Importin-alpha Traffic, 13, 2012
3UKX	Mouse importin alpha: Bimax2 peptide complex Descriptor: Bimax2 peptide, Importin subunit alpha-2 Authors: Marfori, M, Forwood, J.K, Lonhienne, T.G, Kobe, B. Deposit date: 2011-11-10 Release date: 2012-10-03 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural Basis of High-Affinity Nuclear Localization Signal Interactions with Importin-alpha Traffic, 13, 2012
3UKZ	Mouse importin alpha: mouse CBP80 cNLS complex Descriptor: Importin subunit alpha-2, Nuclear cap-binding protein subunit 1 Authors: Marfori, M, Forwood, J.K, Lonhienne, T.G, Kobe, B. Deposit date: 2011-11-10 Release date: 2012-10-03 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural Basis of High-Affinity Nuclear Localization Signal Interactions with Importin-alpha Traffic, 13, 2012

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