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6AS4
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BU of 6as4 by Molmil
Structure of a phage anti-CRISPR protein
Descriptor: NHis AcrE1 anti-crispr protein
Authors:Shah, M, Calmettes, C, Pawluk, A, Mejdani, M, Davidson, A.R, Maxwell, K.L, Moraes, T.F.
Deposit date:2017-08-23
Release date:2017-12-20
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Disabling a Type I-E CRISPR-Cas Nuclease with a Bacteriophage-Encoded Anti-CRISPR Protein.
MBio, 8, 2017
6AS3
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BU of 6as3 by Molmil
Structure of a phage anti-CRISPR protein
Descriptor: NHis AcrE1 protein
Authors:Shah, M, Calmettes, C, Pawluk, A, Mejdani, M, Davidson, A.R, Maxwell, K.L, Moraes, T.F.
Deposit date:2017-08-23
Release date:2018-08-29
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Disabling a Type I-E CRISPR-Cas Nuclease with a Bacteriophage-Encoded Anti-CRISPR Protein.
MBio, 8, 2017
5UZ9
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BU of 5uz9 by Molmil
Cryo EM structure of anti-CRISPRs, AcrF1 and AcrF2, bound to type I-F crRNA-guided CRISPR surveillance complex
Descriptor: Anti-CRISPR protein 30, Anti-CRISPR protein Acr30-35, CRISPR RNA (60-MER), ...
Authors:Chowdhury, S, Carter, J, Rollins, M.F, Jackson, R.N, Hoffmann, C, Nosaka, L, Bondy-Denomy, J, Maxwell, K.L, Davidson, A.R, Fischer, E.R, Lander, G.C, Wiedenheft, B.
Deposit date:2017-02-25
Release date:2017-04-26
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure Reveals Mechanisms of Viral Suppressors that Intercept a CRISPR RNA-Guided Surveillance Complex.
Cell, 169, 2017
4ZA0
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BU of 4za0 by Molmil
Structure of Human Enolase 2 in complex with Phosphonoacetohydroxamate
Descriptor: Gamma-enolase, MAGNESIUM ION, PHOSPHONOACETOHYDROXAMIC ACID
Authors:Leonard, P.G, Maxwell, D, Czako, B, Muller, F.L.
Deposit date:2015-04-13
Release date:2016-04-13
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:SF2312 is a natural phosphonate inhibitor of enolase.
Nat.Chem.Biol., 12, 2016
7M2X
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BU of 7m2x by Molmil
Open conformation of the Yeast wild-type gamma-TuRC
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Spindle pole body component 110, Spindle pole body component SPC97, ...
Authors:Brilot, A.F, Lyon, A.S, Zelter, A, Viswanath, S, Maxwell, A, MacCoss, M.J, Muller, E.G, Sali, A, Davis, T.N, Agard, D.A.
Deposit date:2021-03-17
Release date:2021-05-12
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:CM1-driven assembly and activation of yeast gamma-tubulin small complex underlies microtubule nucleation.
Elife, 10, 2021
7M3P
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BU of 7m3p by Molmil
Xrcc4-Spc110p(164-207) fusion
Descriptor: Xrcc4-Spc110p(164-207)
Authors:Brilot, A.F, Lyon, A.S, Zelter, A, Viswanath, S, Maxwell, A, MacCoss, M.J, Muller, E.G, Sali, A, Davis, T.N, Agard, D.A.
Deposit date:2021-03-18
Release date:2021-05-12
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.0000186 Å)
Cite:CM1-driven assembly and activation of yeast gamma-tubulin small complex underlies microtubule nucleation.
Elife, 10, 2021
7M2Y
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BU of 7m2y by Molmil
Closed conformation of the Yeast wild-type gamma-TuRC
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Spindle pole body component 110, Spindle pole body component SPC97, ...
Authors:Brilot, A.F, Lyon, A.S, Zelter, A, Viswanath, S, Maxwell, A, MacCoss, M.J, Muller, E.G, Sali, A, Davis, T.N, Agard, D.A.
Deposit date:2021-03-17
Release date:2021-05-12
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.03 Å)
Cite:CM1-driven assembly and activation of yeast gamma-tubulin small complex underlies microtubule nucleation.
Elife, 10, 2021
7M2Z
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BU of 7m2z by Molmil
Monomeric single-particle reconstruction of the Yeast gamma-TuSC
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Spindle pole body component SPC97, Spindle pole body component SPC98, ...
Authors:Brilot, A.F, Lyon, A.S, Zelter, A, Viswanath, S, Maxwell, A, MacCoss, M.J, Muller, E.G, Sali, A, Davis, T.N, Agard, D.A.
Deposit date:2021-03-17
Release date:2021-05-12
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:CM1-driven assembly and activation of yeast gamma-tubulin small complex underlies microtubule nucleation.
Elife, 10, 2021
7M2W
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BU of 7m2w by Molmil
Engineered disulfide cross-linked closed conformation of the Yeast gamma-TuRC(SS)
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, Spindle pole body component 110, Spindle pole body component SPC97, ...
Authors:Brilot, A.F, Lyon, A.S, Zelter, A, Viswanath, S, Maxwell, A, MacCoss, M.J, Muller, E.G, Sali, A, Davis, T.N, Agard, D.A.
Deposit date:2021-03-17
Release date:2021-05-12
Last modified:2024-12-25
Method:ELECTRON MICROSCOPY (3 Å)
Cite:CM1-driven assembly and activation of yeast gamma-tubulin small complex underlies microtubule nucleation.
Elife, 10, 2021
4ZCW
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BU of 4zcw by Molmil
Structure of Human Enolase 2 in complex with SF2312
Descriptor: Gamma-enolase, MAGNESIUM ION, [(3S,5S)-1,5-dihydroxy-2-oxopyrrolidin-3-yl]phosphonic acid
Authors:Leonard, P.G, Maxwell, D, Czako, B, Muller, F.L.
Deposit date:2015-04-16
Release date:2016-07-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.992 Å)
Cite:SF2312 is a natural phosphonate inhibitor of enolase.
Nat.Chem.Biol., 12, 2016
7KIX
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BU of 7kix by Molmil
The structure of anti-CRISPR AcrIE2
Descriptor: Anti-CRISPR protein AcrIE2
Authors:Pawluk, A, Davidson, A.R, Maxwell, K.L.
Deposit date:2020-10-25
Release date:2021-05-26
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Anti-CRISPR AcrIE2 Binds the Type I-E CRISPR-Cas Complex But Does Not Block DNA Binding.
J.Mol.Biol., 433, 2021
5BRL
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BU of 5brl by Molmil
Crystal Structure of L124D STARD4
Descriptor: StAR-related lipid transfer protein 4
Authors:Iaea, D.B, Dikiy, I, Kiburu, I, Eliezer, D.E, Maxfield, F.R.
Deposit date:2015-05-31
Release date:2015-07-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.003 Å)
Cite:STARD4 Membrane Interactions and Sterol Binding.
Biochemistry, 54, 2015
7MSL
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BU of 7msl by Molmil
Structure of anti-CRISPR AcrIIC4 from Haemophilus parainfluenzae
Descriptor: AcrIIC4, IODIDE ION
Authors:Pan, C, Maxwell, K.L, Moraes, T.F.
Deposit date:2021-05-11
Release date:2022-03-23
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Structural and Mechanistic Insight into CRISPR-Cas9 Inhibition by Anti-CRISPR Protein AcrIIC4 Hpa.
J.Mol.Biol., 434, 2022
1ZS4
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BU of 1zs4 by Molmil
Structure of bacteriophage lambda cII protein in complex with DNA
Descriptor: DNA - 27mer, Regulatory protein CII
Authors:Jain, D, Kim, Y, Maxwell, K.L, Beasley, S, Gussin, G.N, Edwards, A.M, Darst, S.A.
Deposit date:2005-05-23
Release date:2005-08-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structure of Bacteriophage lambdacII and Its DNA Complex.
Mol.Cell, 19, 2005
1ZPQ
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BU of 1zpq by Molmil
STRUCTURE OF BACTERIOPHAGE LAMBDA CII protein
Descriptor: Regulatory protein CII
Authors:Jain, D, Kim, Y, Maxwell, K.L, Beasley, S, Gussin, G.N, Edwards, A.M, Joachimiak, A, Darst, S.A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2005-05-17
Release date:2005-08-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of Bacteriophage lambdacII and Its DNA Complex.
Mol.Cell, 19, 2005
5W9D
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BU of 5w9d by Molmil
Estrogen Receptor Alpha Ligand Binding Domain C381S, C417S, C530S Mutant in Complex with Endoxifen
Descriptor: Endoxifen, Estrogen receptor
Authors:Fanning, S.W, Greene, G.L.
Deposit date:2017-06-23
Release date:2017-10-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.6464 Å)
Cite:Endoxifen, 4-Hydroxytamoxifen and an Estrogenic Derivative Modulate Estrogen Receptor Complex Mediated Apoptosis in Breast Cancer.
Mol. Pharmacol., 94, 2018
5W9C
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BU of 5w9c by Molmil
Estrogen Receptor Alpha Ligand Binding Domain C381S, C417S, C530S in Complex with 4-hydroxytamoxifen
Descriptor: 4-HYDROXYTAMOXIFEN, Estrogen receptor
Authors:Fanning, S.W, Greene, G.W.
Deposit date:2017-06-23
Release date:2018-06-13
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.802 Å)
Cite:Endoxifen, 4-Hydroxytamoxifen and an Estrogenic Derivative Modulate Estrogen Receptor Complex Mediated Apoptosis in Breast Cancer.
Mol. Pharmacol., 94, 2018
7M1N
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BU of 7m1n by Molmil
Wild-type Hydrogenobacter thermophilus ferredoxin 1
Descriptor: IRON/SULFUR CLUSTER, Putative ferredoxin
Authors:Steindel, P.S, Li, B, Elliott, S.J.
Deposit date:2021-03-13
Release date:2021-07-28
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Maximizing (Electro)catalytic CO2 Reduction with a Ferredoxin-Based Reduction Potential Gradient
Acs Catalysis, 11, 2021
7M1O
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BU of 7m1o by Molmil
Hydrogenobacter thermophilus ferredoxin 1 S64A variant
Descriptor: IRON/SULFUR CLUSTER, Putative ferredoxin
Authors:Steindel, P.S, Li, B, Elliott, S.J.
Deposit date:2021-03-13
Release date:2021-07-28
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.98388708 Å)
Cite:Maximizing (Electro)catalytic CO2 Reduction with a Ferredoxin-Based Reduction Potential Gradient
Acs Catalysis, 11, 2021
5GIO
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BU of 5gio by Molmil
Crystal structure of box C/D RNP with 12 nt guide regions and 13 nt substrates
Descriptor: 50S ribosomal protein L7Ae, C/D RNA, C/D box methylation guide ribonucleoprotein complex aNOP56 subunit, ...
Authors:Yang, Z, Lin, J, Ye, K.
Deposit date:2016-06-24
Release date:2016-09-14
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.604 Å)
Cite:Box C/D guide RNAs recognize a maximum of 10 nt of substrates
Proc.Natl.Acad.Sci.USA, 113, 2016
5GIN
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BU of 5gin by Molmil
Crystal structure of box C/D RNP with 12 nt guide regions and 9 nt substrates
Descriptor: 50S ribosomal protein L7Ae, C/D RNA, C/D box methylation guide ribonucleoprotein complex aNOP56 subunit, ...
Authors:Yang, Z, Lin, J, Ye, K.
Deposit date:2016-06-24
Release date:2016-09-14
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.308 Å)
Cite:Box C/D guide RNAs recognize a maximum of 10 nt of substrates
Proc.Natl.Acad.Sci.USA, 113, 2016
5NJA
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BU of 5nja by Molmil
E. coli Microcin-processing metalloprotease TldD/E with angiotensin analogue bound
Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, HIS-PRO-PHE, ...
Authors:Ghilarov, D, Serebryakova, M, Stevenson, C.E.M, Hearnshaw, S.J, Volkov, D, Maxwell, A, Lawson, D.M, Severinov, K.
Deposit date:2017-03-28
Release date:2017-10-04
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:The Origins of Specificity in the Microcin-Processing Protease TldD/E.
Structure, 25, 2017
5NH3
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BU of 5nh3 by Molmil
CRYSTAL STRUCTURE OF THE Activin receptor type-2A LIGAND BINDING DOMAIN IN COMPLEX WITH BIMAGRUMAB FV
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Activin receptor type-2A, ...
Authors:Scheufler, C.
Deposit date:2017-03-21
Release date:2017-11-15
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Blockade of activin type II receptors with a dual anti-ActRIIA/IIB antibody is critical to promote maximal skeletal muscle hypertrophy.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5NJF
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BU of 5njf by Molmil
E. coli Microcin-processing metalloprotease TldD/E (TldD H262A mutant) with pentapeptide bound
Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ALA-ALA-ALA-ALA-ALA, ...
Authors:Ghilarov, D, Serebryakova, M, Stevenson, C.E.M, Hearnshaw, S.J, Volkov, D, Maxwell, A, Lawson, D.M, Severinov, K.
Deposit date:2017-03-28
Release date:2017-10-04
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:The Origins of Specificity in the Microcin-Processing Protease TldD/E.
Structure, 25, 2017
5NGV
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BU of 5ngv by Molmil
CRYSTAL STRUCTURE OF THE Activin receptor type-2B LIGAND BINDING DOMAIN IN COMPLEX WITH BIMAGRUMAB FV, ORTHORHOMBIC CRYSTAL FORM
Descriptor: Activin receptor type-2B, TETRAETHYLENE GLYCOL, anti-human ActRIIB mAb BYM338 heavy-chain, ...
Authors:Rondeau, J.-M, Lehmann, S.
Deposit date:2017-03-20
Release date:2017-11-15
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Blockade of activin type II receptors with a dual anti-ActRIIA/IIB antibody is critical to promote maximal skeletal muscle hypertrophy.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017

238582

数据于2025-07-09公开中

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