PDB: 73332 resultsInfo pagesStatus searchChemie searchBIRD

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5W1H	Crystal structure of LbaCas13a (C2c2) bound to mature crRNA (24-nt spacer) Descriptor: GLYCEROL, IODIDE ION, LbaCas13a (C2c2), ... Authors: Knott, G.J, Doudna, J.A. Deposit date: 2017-06-03 Release date: 2017-09-13 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.99 Å) Cite: Guide-bound structures of an RNA-targeting A-cleaving CRISPR-Cas13a enzyme. Nat. Struct. Mol. Biol., 24, 2017
5W1I	Crystal structure of LbaCas13a (C2c2) bound to mature crRNA (20-nt spacer) Descriptor: IODIDE ION, LbaCas13a (C2c2), mature crRNA Authors: Knott, G.J, Doudna, J.A. Deposit date: 2017-06-03 Release date: 2017-09-13 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Guide-bound structures of an RNA-targeting A-cleaving CRISPR-Cas13a enzyme. Nat. Struct. Mol. Biol., 24, 2017
5LZA	Structure of the 70S ribosome with SECIS-mRNA and P-site tRNA (Initial complex, IC) Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... Authors: Fischer, N, Neumann, P, Bock, L.V, Maracci, C, Wang, Z, Paleskava, A, Konevega, A.L, Schroeder, G.F, Grubmueller, H, Ficner, R, Rodnina, M.V, Stark, H. Deposit date: 2016-09-29 Release date: 2016-11-23 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: The pathway to GTPase activation of elongation factor SelB on the ribosome. Nature, 540, 2016
6D6R	Human nuclear exosome-MTR4 RNA complex - composite map after focused reconstruction Descriptor: DNA/RNA (62-MER), Exosome RNA helicase MTR4, Exosome complex component CSL4, ... Authors: Weick, E.-M, Lima, C.D. Deposit date: 2018-04-22 Release date: 2018-06-20 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (3.45 Å) Cite: Helicase-Dependent RNA Decay Illuminated by a Cryo-EM Structure of a Human Nuclear RNA Exosome-MTR4 Complex. Cell, 173, 2018
6D6Q	Human nuclear exosome-MTR4 RNA complex - overall reconstruction Descriptor: DNA/RNA (62-MER), Exosome RNA helicase MTR4, Exosome complex component CSL4, ... Authors: Weick, E.-M, Lima, C.D. Deposit date: 2018-04-22 Release date: 2018-06-20 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (3.45 Å) Cite: Helicase-Dependent RNA Decay Illuminated by a Cryo-EM Structure of a Human Nuclear RNA Exosome-MTR4 Complex. Cell, 173, 2018
5LTK	Crystal structure of the Prp43-ADP-BeF3 complex (in hexagonal space group) Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... Authors: Tauchert, M.J, Ficner, R. Deposit date: 2016-09-06 Release date: 2017-01-25 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (3.241 Å) Cite: Structural insights into the mechanism of the DEAH-box RNA helicase Prp43. Elife, 6, 2017
4MGM	Crystal structure of the in vitro transcribed G. kaustophilus tRNA-Gly Descriptor: MAGNESIUM ION, tRNA glycine Authors: Grigg, J.C, Ke, A. Deposit date: 2013-08-28 Release date: 2013-10-23 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Structural Determinants for Geometry and Information Decoding of tRNA by T Box Leader RNA. Structure, 21, 2013
4MDX	Crystal structure of Bacillus subtilis MazF in complex with RNA Descriptor: IODIDE ION, RNA, mRNA, ... Authors: Simanshu, D.K, Patel, D.J. Deposit date: 2013-08-23 Release date: 2013-10-23 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Structural Basis of mRNA Recognition and Cleavage by Toxin MazF and Its Regulation by Antitoxin MazE in Bacillus subtilis. Mol.Cell, 52, 2013
5E81	Structure of T. thermophilus 70S ribosome complex with mRNA and tRNALys in the A-site with wobble pair Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... Authors: Rozov, A, Demeshkina, N, Khusainov, I, Yusupov, M, Yusupova, G. Deposit date: 2015-10-13 Release date: 2016-01-27 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.95 Å) Cite: Novel base-pairing interactions at the tRNA wobble position crucial for accurate reading of the genetic code. Nat Commun, 7, 2016
5EL4	Structure of T. thermophilus 70S ribosome complex with mRNA and tRNALys in the A-site with a U-U mismatch in the first position Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... Authors: Rozov, A, Demeshkina, N, Khusainov, I, Yusupov, M, Yusupova, G. Deposit date: 2015-11-04 Release date: 2016-01-27 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.15 Å) Cite: Novel base-pairing interactions at the tRNA wobble position crucial for accurate reading of the genetic code. Nat Commun, 7, 2016
5EL5	Structure of T. thermophilus 70S ribosome complex with mRNA and tRNALys in the A-site with a U-U mismatch in the second position Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... Authors: Rozov, A, Demeshkina, N, Khusainov, I, Yusupov, M, Yusupova, G. Deposit date: 2015-11-04 Release date: 2016-01-27 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.15 Å) Cite: Novel base-pairing interactions at the tRNA wobble position crucial for accurate reading of the genetic code. Nat Commun, 7, 2016
3EQT	Crystal structure of human LGP2 C-terminal domain in complex with dsRNA Descriptor: 5'-R(*GP*CP*GP*CP*GP*CP*GP*C)-3', ATP-dependent RNA helicase DHX58, ZINC ION Authors: Li, P, Li, X. Deposit date: 2008-10-01 Release date: 2009-03-10 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2 Å) Cite: The RIG-I-like Receptor LGP2 Recognizes the Termini of Double-stranded RNA J.Biol.Chem., 284, 2009
8CDL	80S S. cerevisiae ribosome with ligands in hybrid-2 pre-translocation (PRE-H2) complex Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... Authors: Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G. Deposit date: 2023-01-31 Release date: 2023-09-20 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (2.72 Å) Cite: mRNA reading frame maintenance during eukaryotic ribosome translocation. Nature, 625, 2024
8CDR	Translocation intermediate 2 (TI-2) of 80S S. cerevisiae ribosome with ligands and eEF2 in the presence of sordarin Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... Authors: Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G. Deposit date: 2023-01-31 Release date: 2023-09-20 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (2.04 Å) Cite: mRNA reading frame maintenance during eukaryotic ribosome translocation. Nature, 625, 2024
8CF5	Translocation intermediate 1 (TI-1) of 80S S. cerevisiae ribosome with ligands and eEF2 in the presence of sordarin Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... Authors: Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G. Deposit date: 2023-02-02 Release date: 2023-09-20 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (2.71 Å) Cite: mRNA reading frame maintenance during eukaryotic ribosome translocation. Nature, 625, 2024
8CCS	80S S. cerevisiae ribosome with ligands in hybrid-1 pre-translocation (PRE-H1) complex Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... Authors: Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G. Deposit date: 2023-01-27 Release date: 2023-09-20 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (1.97 Å) Cite: mRNA reading frame maintenance during eukaryotic ribosome translocation. Nature, 625, 2024
8CKU	Translocation intermediate 1 (TI-1*) of 80S S. cerevisiae ribosome with ligands and eEF2 in the absence of sordarin Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... Authors: Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G. Deposit date: 2023-02-16 Release date: 2023-09-20 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (3.11 Å) Cite: mRNA reading frame maintenance during eukaryotic ribosome translocation. Nature, 625, 2024
8CIV	Translocation intermediate 5 (TI-5) of 80S S. cerevisiae ribosome with ligands and eEF2 in the presence of sordarin Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... Authors: Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G. Deposit date: 2023-02-10 Release date: 2023-09-20 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (2.47 Å) Cite: mRNA reading frame maintenance during eukaryotic ribosome translocation. Nature, 625, 2024
8CG8	Translocation intermediate 3 (TI-3) of 80S S. cerevisiae ribosome with ligands and eEF2 in the presence of sordarin Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... Authors: Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G. Deposit date: 2023-02-03 Release date: 2023-09-20 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (2.57 Å) Cite: mRNA reading frame maintenance during eukaryotic ribosome translocation. Nature, 625, 2024
8CEH	Translocation intermediate 4 (TI-4) of 80S S. cerevisiae ribosome with ligands and eEF2 in the presence of sordarin Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... Authors: Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G. Deposit date: 2023-02-01 Release date: 2023-09-20 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (2.05 Å) Cite: mRNA reading frame maintenance during eukaryotic ribosome translocation. Nature, 625, 2024
8CGN	Non-rotated 80S S. cerevisiae ribosome with ligands Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... Authors: Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G. Deposit date: 2023-02-06 Release date: 2023-09-20 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (2.28 Å) Cite: mRNA reading frame maintenance during eukaryotic ribosome translocation. Nature, 625, 2024
2IL9	Crystal Structure of Plautia Stali Intestine Virus Intergenic Region Internal Ribosome Entry Site Ribosomal Binding Domain RNA at 3.1 Angstroms Descriptor: Ribosomal Binding Domain of the IRES RNA Authors: Pfingsten, J.S, Costantino, D.A, Kieft, J.S. Deposit date: 2006-10-02 Release date: 2007-02-13 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Structural basis for ribosome recruitment and manipulation by a viral IRES RNA Science, 314, 2006
3O3I	Crystal Structure of human Hiwi1 PAZ domain (residues 277-399) in complex with 14-mer RNA (12-bp + 2-nt overhang) containing 2'-OH at its 3'-end Descriptor: Piwi-like protein 1, RNA (5'-R(*GP*CP*GP*AP*AP*UP*AP*UP*UP*CP*GP*CP*UP*U)-3') Authors: Tian, Y, Simanshu, D.K, Ma, J.-B, Patel, D.J. Deposit date: 2010-07-24 Release date: 2011-01-12 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.801 Å) Cite: Inaugural Article: Structural basis for piRNA 2'-O-methylated 3'-end recognition by Piwi PAZ (Piwi/Argonaute/Zwille) domains. Proc.Natl.Acad.Sci.USA, 108, 2011
8CMJ	Translocation intermediate 4 (TI-4*) of 80S S. cerevisiae ribosome with eEF2 in the absence of sordarin Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... Authors: Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G. Deposit date: 2023-02-20 Release date: 2023-09-20 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (3.79 Å) Cite: mRNA reading frame maintenance during eukaryotic ribosome translocation. Nature, 625, 2024
5LYB	Crystal structure of the S.cerevisiae 80S ribosome in complex with the A-site bound aminoacyl-tRNA analog ACCPmn Descriptor: 18S rRNA, 25S rRNA, 40S Ribosomal Protein S12, ... Authors: Melnikov, S, Mailliot, J. Deposit date: 2016-09-26 Release date: 2016-11-23 Last modified: 2016-12-14 Method: X-RAY DIFFRACTION (3.25 Å) Cite: Molecular insights into protein synthesis with proline residues. EMBO Rep., 17, 2016

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