5EMZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5emz by Molmil](/molmil-images/mine/5emz) | |
5AF5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5af5 by Molmil](/molmil-images/mine/5af5) | Structure of Lys33-linked triUb S.G. P 212121 | Descriptor: | POLYUBIQUITIN-C | Authors: | Michel, M.A, Elliott, P.R, Swatek, K.N, Simicek, M, Pruneda, J.N, Wagstaff, J.L, Freund, S.M.V, Komander, D. | Deposit date: | 2015-01-19 | Release date: | 2015-03-25 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Assembly and Specific Recognition of K29- and K33-Linked Polyubiquitin. Mol.Cell, 58, 2015
|
|
3VUX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3vux by Molmil](/molmil-images/mine/3vux) | Crystal structure of A20 ZF7 in complex with linear ubiquitin, form II | Descriptor: | 1,2-ETHANEDIOL, POTASSIUM ION, Polyubiquitin-C, ... | Authors: | Nishimasu, H, Ishitani, R, Nureki, O. | Deposit date: | 2012-07-09 | Release date: | 2013-02-13 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.699 Å) | Cite: | Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-kappaB regulation Embo J., 31, 2012
|
|
6B7M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6b7m by Molmil](/molmil-images/mine/6b7m) | |
6HPR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6hpr by Molmil](/molmil-images/mine/6hpr) | |
5NMC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5nmc by Molmil](/molmil-images/mine/5nmc) | |
8E7O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8e7o by Molmil](/molmil-images/mine/8e7o) | CRYSTAL STRUCTURE OF LYS48-LINKED TETRAUBIQUITIN | Descriptor: | SULFATE ION, Ubiquitin | Authors: | Lemma, B.E, Fushman, D. | Deposit date: | 2022-08-24 | Release date: | 2022-11-02 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Mechanism of selective recognition of Lys48-linked polyubiquitin by macrocyclic peptide inhibitors of proteasomal degradation. Nat Commun, 14, 2023
|
|
3V6C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3v6c by Molmil](/molmil-images/mine/3v6c) | Crystal Structure of USP2 in complex with mutated ubiquitin | Descriptor: | CHLORIDE ION, GLYCEROL, Ubiquitin, ... | Authors: | Neculai, M, Ernst, A, Sidhu, S, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | Deposit date: | 2011-12-19 | Release date: | 2012-12-19 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal Structure of USP2 in complex with mutated ubiquitin To be Published
|
|
3B08
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3b08 by Molmil](/molmil-images/mine/3b08) | Crystal structure of the mouse HOIL1-L-NZF in complex with linear di-ubiquitin | Descriptor: | Polyubiquitin-C, RanBP-type and C3HC4-type zinc finger-containing protein 1, ZINC ION, ... | Authors: | Sato, Y, Fujita, H, Yoshikawa, A, Yamashita, M, Yamagata, A, Kaiser, S.E, Iwai, K, Fukai, S. | Deposit date: | 2011-06-07 | Release date: | 2011-12-14 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.701 Å) | Cite: | Specific recognition of linear ubiquitin chains by the Npl4 zinc finger (NZF) domain of the HOIL-1L subunit of the linear ubiquitin chain assembly complex Proc.Natl.Acad.Sci.USA, 108, 2011
|
|
4I6N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4i6n by Molmil](/molmil-images/mine/4i6n) | Crystal structure of Trichinella spiralis UCH37 catalytic domain bound to Ubiquitin vinyl methyl ester | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, METHYL 4-AMINOBUTANOATE, SODIUM ION, ... | Authors: | Morrow, M.E, Ronau, J.A, White, R.R, Artavanis-Tsakonas, K, Das, C. | Deposit date: | 2012-11-29 | Release date: | 2013-05-29 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.701 Å) | Cite: | Stabilization of an Unusual Salt Bridge in Ubiquitin by the Extra C-Terminal Domain of the Proteasome-Associated Deubiquitinase UCH37 as a Mechanism of Its Exo Specificity. Biochemistry, 52, 2013
|
|
3NS8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ns8 by Molmil](/molmil-images/mine/3ns8) | |
7OWD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7owd by Molmil](/molmil-images/mine/7owd) | |
4ZFR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4zfr by Molmil](/molmil-images/mine/4zfr) | Catalytic domain of Sst2 F403A mutant bound to ubiquitin | Descriptor: | 1,2-ETHANEDIOL, AMSH-like protease sst2, ZINC ION, ... | Authors: | Shrestha, R.K. | Deposit date: | 2015-04-21 | Release date: | 2015-10-14 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | Structure of Catalytic domain of Sst2 F403A mutant bound to ubiquitin at 1.7 Angstroms To Be Published
|
|
8ADB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8adb by Molmil](/molmil-images/mine/8adb) | Viral tegument-like DUBs | Descriptor: | CITRIC ACID, Polyubiquitin-C, Wc-VDT1, ... | Authors: | Erven, I, Abraham, E.T, Hermanns, T, Baumann, U, Hofmann, K. | Deposit date: | 2022-07-08 | Release date: | 2023-02-15 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | A widely distributed family of eukaryotic and bacterial deubiquitinases related to herpesviral large tegument proteins. Nat Commun, 13, 2022
|
|
6EI1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ei1 by Molmil](/molmil-images/mine/6ei1) | Crystal structure of the covalent complex between deubiquitinase ZUFSP (ZUP1) and Ubiquitin-PA | Descriptor: | GLYCEROL, MALONATE ION, Polyubiquitin-B, ... | Authors: | Pichlo, C, Baumann, U, Hofmann, K, Hermanns, T. | Deposit date: | 2017-09-16 | Release date: | 2018-03-07 | Last modified: | 2019-10-16 | Method: | X-RAY DIFFRACTION (1.732 Å) | Cite: | A family of unconventional deubiquitinases with modular chain specificity determinants. Nat Commun, 9, 2018
|
|
5GOC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5goc by Molmil](/molmil-images/mine/5goc) | Lys11-linked diubiquitin | Descriptor: | D-ubiquitin, SODIUM ION, Ubiquitin | Authors: | Gao, S, Pan, M, Zheng, Y. | Deposit date: | 2016-07-26 | Release date: | 2016-11-02 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.733 Å) | Cite: | Monomer/Oligomer Quasi-Racemic Protein Crystallography J.Am.Chem.Soc., 138, 2016
|
|
6FGE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6fge by Molmil](/molmil-images/mine/6fge) | Crystal structure of human ZUFSP/ZUP1 in complex with ubiquitin | Descriptor: | ACETATE ION, AMMONIUM ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Kwasna, D, Abdul Rehman, S.A, Kulathu, Y. | Deposit date: | 2018-01-10 | Release date: | 2018-04-04 | Last modified: | 2018-04-18 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability. Mol. Cell, 70, 2018
|
|
4MSM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4msm by Molmil](/molmil-images/mine/4msm) | Crystal structure of Schizosaccharomyces pombe AMSH-like protease sst2 E286A mutant bound to ubiquitin | Descriptor: | 1,2-ETHANEDIOL, AMSH-like protease sst2, PHOSPHATE ION, ... | Authors: | Shrestha, R.K, Ronau, J.A, Das, C. | Deposit date: | 2013-09-18 | Release date: | 2014-06-18 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Insights into the Mechanism of Deubiquitination by JAMM Deubiquitinases from Cocrystal Structures of the Enzyme with the Substrate and Product. Biochemistry, 53, 2014
|
|
9AVW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 9avw by Molmil](/molmil-images/mine/9avw) | |
8ST8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8st8 by Molmil](/molmil-images/mine/8st8) | |
8T2D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8t2d by Molmil](/molmil-images/mine/8t2d) | Ubiquitin variant i53:Mutant T12Y.T14E.L67R with 53BP1 Tudor domain | Descriptor: | Tumor protein p53 binding protein 1, Ubiquitin variant i53 | Authors: | Partridge, J.R, Holden, J.K, Wibowo, A.S, Mulichak, A. | Deposit date: | 2023-06-05 | Release date: | 2024-03-27 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.751 Å) | Cite: | Functional screening in human HSPCs identifies optimized protein-based enhancers of Homology Directed Repair. Nat Commun, 15, 2024
|
|
4K7U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4k7u by Molmil](/molmil-images/mine/4k7u) | Crystal structure of Zn2.3-hUb (human ubiquitin) adduct from a solution 70 mM zinc acetate/1.3 mM hUb | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Fermani, S, Falini, G, Calvaresi, M, Bottoni, A, Arnesano, F, Natile, G. | Deposit date: | 2013-04-17 | Release date: | 2013-05-08 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Conformational selection of ubiquitin quaternary structures driven by zinc ions. Chemistry, 19, 2013
|
|
4K7S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4k7s by Molmil](/molmil-images/mine/4k7s) | Crystal structure of Zn2-hUb (human ubiquitin) adduct from a solution 35 mM zinc acetate/1.3 mM hUb | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, ZINC ION, ... | Authors: | Fermani, S, Falini, G, Calvaresi, M, Bottoni, A, Arnesano, F, Natile, G. | Deposit date: | 2013-04-17 | Release date: | 2013-05-08 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Conformational selection of ubiquitin quaternary structures driven by zinc ions. Chemistry, 19, 2013
|
|
4K7W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4k7w by Molmil](/molmil-images/mine/4k7w) | Crystal structure of Zn3-hUb(human ubiquitin) adduct from a solution 100 mM zinc acetate/1.3 mM hUb | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, ZINC ION, ... | Authors: | Fermani, S, Falini, G, Calvaresi, M, Bottoni, A, Arnesano, F, Natile, G. | Deposit date: | 2013-04-17 | Release date: | 2013-05-08 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Conformational selection of ubiquitin quaternary structures driven by zinc ions. Chemistry, 19, 2013
|
|
6OI4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6oi4 by Molmil](/molmil-images/mine/6oi4) | RPN13 (19-132)-RPN2 (940-952) pY950-Ub complex | Descriptor: | 1,2-ETHANEDIOL, 26S proteasome non-ATPase regulatory subunit 1, Proteasomal ubiquitin receptor ADRM1, ... | Authors: | Hemmis, C.W, Hill, C.P. | Deposit date: | 2019-04-08 | Release date: | 2019-05-15 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Phosphorylation of Tyr-950 in the proteasome scaffolding protein RPN2 modulates its interaction with the ubiquitin receptor RPN13. J.Biol.Chem., 294, 2019
|
|