4I6N

Crystal structure of Trichinella spiralis UCH37 catalytic domain bound to Ubiquitin vinyl methyl ester

Summary for 4I6N

Related3IHR
DescriptorUbiquitin carboxyl-hydrolase, Ubiquitin, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ... (6 entities in total)
Functional Keywordshelix-beta-helix sandwich, protein-protein complex, deubiquitination, ubiquitin c-terminal hydrolase, cytosol, hydrolase-signaling protein complex, hydrolase/signaling protein
Biological sourceTrichinella spiralis (Trichina worm)
More
Cellular locationUbiquitin: Cytoplasm (By similarity) P0CG48
Total number of polymer chains4
Total molecular weight70074.88
Authors
Morrow, M.E.,Ronau, J.A.,White, R.R.,Artavanis-Tsakonas, K.,Das, C. (deposition date: 2012-11-29, release date: 2013-05-29)
Primary citation
Morrow, M.E.,Kim, M.I.,Ronau, J.A.,Sheedlo, M.J.,White, R.R.,Chaney, J.,Paul, L.N.,Lill, M.A.,Artavanis-Tsakonas, K.,Das, C.
Stabilization of an Unusual Salt Bridge in Ubiquitin by the Extra C-Terminal Domain of the Proteasome-Associated Deubiquitinase UCH37 as a Mechanism of Its Exo Specificity.
Biochemistry, 52:3564-3578, 2013
PubMed: 23617878 (PDB entries with the same primary citation)
DOI: 10.1021/bi4003106
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.701 Å)
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.21550.3%1.9%5.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report