5X1C
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8HFD
| Crystal structure of allantoinase from E. coli BL21 | Descriptor: | Allantoinase, DI(HYDROXYETHYL)ETHER, ZINC ION | Authors: | Lin, E.S, Huang, H.Y, Yang, P.C, Liu, H.W, Huang, C.Y. | Deposit date: | 2022-11-10 | Release date: | 2023-10-18 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | Crystal Structure of Allantoinase from Escherichia coli BL21: A Molecular Insight into a Role of the Active Site Loops in Catalysis. Molecules, 28, 2023
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8WQ9
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8DNM
| Human Brain Dihydropyrimidinase-related protein 2 | Descriptor: | Dihydropyrimidinase-related protein 2 | Authors: | Tringides, M.L. | Deposit date: | 2022-07-11 | Release date: | 2022-11-16 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2.76 Å) | Cite: | A cryo-electron microscopic approach to elucidate protein structures from human brain microsomes. Life Sci Alliance, 6, 2023
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5E5C
| Crystal structure of dihydropyrimidinase from Pseudomonas aeruginosa PAO1 | Descriptor: | D-hydantoinase/dihydropyrimidinase, ZINC ION | Authors: | Huang, C.C, Huang, Y.H, Hsieh, Y.C, Tzeng, C.T, Chen, C.J, Huang, C.Y. | Deposit date: | 2015-10-08 | Release date: | 2016-09-21 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of dihydropyrimidinase from Pseudomonas aeruginosa PAO1: Insights into the molecular basis of formation of a dimer Biochem.Biophys.Res.Commun., 478, 2016
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6AJD
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7X68
| CYS179 and CYS504 of CRMP2 were covalently binded by a Sesquiterpene lactone | Descriptor: | (3aR,5S,8R,8aR,9aR)-5,8a-dimethyl-3-methylidene-8-oxidanyl-5,6,7,8,9,9a-hexahydro-3aH-benzo[f][1]benzofuran-2-one, Dihydropyrimidinase-related protein 2, SODIUM ION | Authors: | Zhang, S.D, Ma, Y.F, Zhang, J. | Deposit date: | 2022-03-06 | Release date: | 2022-05-04 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | CYS179 and CYS504 of CRMP2 were covalently binded by a Sesquiterpene lactone To Be Published
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7U5K
| Cryo-EM Structure of DPYSL2 | Descriptor: | Dihydropyrimidinase-related protein 2 | Authors: | Morgan, C.E, Yu, E.W. | Deposit date: | 2022-03-02 | Release date: | 2022-12-14 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2.78 Å) | Cite: | Toward structural-omics of the bovine retinal pigment epithelium. Cell Rep, 41, 2022
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7WW2
| Structure of an Isocytosine specific deaminase Vcz | Descriptor: | 8-oxoguanine deaminase, ZINC ION | Authors: | Li, X.J, Wu, B.X. | Deposit date: | 2022-02-12 | Release date: | 2023-02-22 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural characterization of an isocytosine-specific deaminase VCZ reveals its application potential in the anti-cancer therapy. Iscience, 26, 2023
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7UOF
| Dihydroorotase from M. jannaschii | Descriptor: | Dihydroorotase, ZINC ION | Authors: | Vitali, J, Nix, J.C, Newman, H.E, Colaneri, M.J. | Deposit date: | 2022-04-12 | Release date: | 2022-08-31 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of Methanococcus jannaschii dihydroorotase. Proteins, 91, 2023
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5LP3
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6CTY
| Crystal structure of dihydroorotase pyrC from Yersinia pestis in complex with zinc and malate at 2.4 A resolution | Descriptor: | D-MALATE, Dihydroorotase, ZINC ION | Authors: | Lipowska, J, Shabalin, I.G, Winsor, J, Woinska, M, Cooper, D.R, Kwon, K, Shuvalova, L, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2018-03-23 | Release date: | 2018-04-04 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Pyrimidine biosynthesis in pathogens - Structures and analysis of dihydroorotases from Yersinia pestis and Vibrio cholerae. Int.J.Biol.Macromol., 136, 2019
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6OH9
| Yeast Guanine Deaminase | Descriptor: | NONAETHYLENE GLYCOL, SULFATE ION, Yeast Guanine Deaminase, ... | Authors: | Shek, R.S, French, J.B. | Deposit date: | 2019-04-05 | Release date: | 2019-07-24 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural Determinants for Substrate Selectivity in Guanine Deaminase Enzymes of the Amidohydrolase Superfamily. Biochemistry, 58, 2019
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5LXX
| High-resolution structure of human collapsin response mediator protein 2 | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Dihydropyrimidinase-related protein 2, SULFATE ION | Authors: | Myllykoski, M, Hensley, K, Kursula, P. | Deposit date: | 2016-09-23 | Release date: | 2017-01-11 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Collapsin response mediator protein 2: high-resolution crystal structure sheds light on small-molecule binding, post-translational modifications, and conformational flexibility. Amino Acids, 49, 2017
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6OHC
| E. coli Guanine Deaminase | Descriptor: | GLYCEROL, Guanine deaminase, ZINC ION | Authors: | Shek, R.S, French, J.B. | Deposit date: | 2019-04-05 | Release date: | 2019-07-24 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural Determinants for Substrate Selectivity in Guanine Deaminase Enzymes of the Amidohydrolase Superfamily. Biochemistry, 58, 2019
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4RDV
| The structure of N-formimino-L-Glutamate Iminohydrolase from Pseudomonas aeruginosa complexed with N-formimino-L-Aspartate | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, N-FORMIMINO-L-GLUTAMATE IMINOHYDROLASE, ... | Authors: | Fedorov, A.A, Fedorov, E.V, Marti-Arbona, R, Raushel, F.M, Almo, S.C. | Deposit date: | 2014-09-19 | Release date: | 2014-10-08 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | The structure of N-formimino-L-Glutamate Iminohydrolase from Pseudomonas aeruginosa complexed with N-formimino-L-Aspartate To be Published
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4RDW
| The structure of N-formimino-L-Glutamate Iminohydrolase from Pseudomonas aeruginosa complexed with N-Guanidino-L-Glutaric acid | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | Authors: | Fedorov, A.A, Fedorov, E.V, Marti-Arbona, R, Raushel, F.M, Almo, S.C. | Deposit date: | 2014-09-19 | Release date: | 2014-10-08 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.591 Å) | Cite: | The structure of N-formimino-L-Glutamate Iminohydrolase from Pseudomonas aeruginosa complexed with N-Guanidino-L-Glutaric acid To be Published
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7CDH
| Crystal structure of Betaaspartyl dipeptidase from thermophilic keratin degrading Fervidobacterium islandicum-AW-1 | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Isoaspartyl dipeptidase, ... | Authors: | Dhanasingh, I, La, J.W, Lee, D.W, Lee, S.H. | Deposit date: | 2020-06-19 | Release date: | 2020-12-30 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Functional Characterization of Primordial Protein Repair Enzyme M38 Metallo-Peptidase From Fervidobacterium islandicum AW-1. Front Mol Biosci, 7, 2020
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4YIW
| DIHYDROOROTASE FROM BACILLUS ANTHRACIS WITH SUBSTRATE BOUND | Descriptor: | Dihydroorotase, N-CARBAMOYL-L-ASPARTATE, ZINC ION | Authors: | Lei, H, Santarsiero, B.D, Rice, A.J, Lee, H, Johnson, M.E. | Deposit date: | 2015-03-02 | Release date: | 2016-08-10 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Ca-asp bound X-ray structure and inhibition of Bacillus anthracis dihydroorotase (DHOase). Bioorg.Med.Chem., 24, 2016
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7E3U
| Crystal structure of the Pseudomonas aeruginosa dihydropyrimidinase complexed with 5-AU | Descriptor: | 5-AMINO-1H-PYRIMIDINE-2,4-DIONE, D-hydantoinase/dihydropyrimidinase, ZINC ION | Authors: | Yang, Y.C, Luo, R.H, Huang, Y.H, Huang, C.Y, Lin, E.S. | Deposit date: | 2021-02-09 | Release date: | 2022-02-16 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.159 Å) | Cite: | Molecular Insights into How the Dimetal Center in Dihydropyrimidinase Can Bind the Thymine Antagonist 5-Aminouracil: A Different Binding Mode from the Anticancer Drug 5-Fluorouracil. Bioinorg Chem Appl, 2022, 2022
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7CF6
| Crystal structure of Beta-aspartyl dipeptidase from thermophilic keratin degrading Fervidobacterium islandicum AW-1 in complex with beta-Asp-Leu dipeptide | Descriptor: | (2S)-2-[[(3S)-3-azanyl-4-oxidanyl-4-oxidanylidene-butanoyl]amino]-4-methyl-pentanoic acid, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | Authors: | Dhanasingh, I, La, J.W, Lee, D.W, Lee, S.H. | Deposit date: | 2020-06-24 | Release date: | 2020-12-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Functional Characterization of Primordial Protein Repair Enzyme M38 Metallo-Peptidase From Fervidobacterium islandicum AW-1. Front Mol Biosci, 7, 2020
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4RZB
| The structure of N-formimino-L-Glutamate Iminohydrolase from Pseudomonas aeruginosa complexed with N-formimino-L-Aspartate, SOAKED WITH MERCURY | Descriptor: | GLYCEROL, MERCURY (II) ION, N-[(E)-iminomethyl]-L-aspartic acid, ... | Authors: | Fedorov, A.A, Fedorov, E.V, Marti-Arbona, R, Raushel, F.M, Almo, S.C. | Deposit date: | 2014-12-19 | Release date: | 2015-01-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.863 Å) | Cite: | Structure of N-Formimino-l-glutamate Iminohydrolase from Pseudomonas aeruginosa. Biochemistry, 54, 2015
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4F0L
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4F0R
| Crystal structure of an adenosine deaminase homolog from Chromobacterium violaceum (target NYSGRC-019589) bound Zn and 5'-Methylthioadenosine (unproductive complex) | Descriptor: | 5'-DEOXY-5'-METHYLTHIOADENOSINE, 5-methylthioadenosine/S-adenosylhomocysteine deaminase, GLYCEROL, ... | Authors: | Kim, J, Vetting, M.W, Sauder, J.M, Burley, S.K, Raushel, F.M, Bonanno, J.B, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2012-05-04 | Release date: | 2012-06-06 | Last modified: | 2021-02-10 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of an adenosine deaminase homolog from Chromobacterium violaceum (target NYSGRC-019589) bound Zn and 5'-Methylthioadenosine (unproductive complex) To be Published
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4TQT
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