6KLK

Crystal structure of the Pseudomonas aeruginosa dihydropyrimidinase complexed with 5-FU

Summary for 6KLK

Entry DOI	10.2210/pdb6klk/pdb
Descriptor	D-hydantoinase/dihydropyrimidinase, 5-FLUOROURACIL, ZINC ION, ... (4 entities in total)
Functional Keywords	hydrolase, dihydropyrimidinase
Biological source	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Total number of polymer chains	2
Total formula weight	105023.40
Authors	Huang, Y.H.,Chen, I.C.,Huang, C.Y. (deposition date: 2019-07-30, release date: 2019-11-06, Last modification date: 2023-11-22)
Primary citation	Huang, Y.H.,Ning, Z.J.,Huang, C.Y. Crystal structure of dihydropyrimidinase in complex with anticancer drug 5-fluorouracil. Biochem.Biophys.Res.Commun., 519:160-165, 2019 Cited by PubMed: 31481233 DOI: 10.1016/j.bbrc.2019.08.153 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.759 Å)

Structure validation