7NUT

Crystal structure of human AMDHD2 in complex with Zn and GlcN6P

Summary for 7NUT

• Entry DOI: 10.2210/pdb7nut/pdb
• Descriptor: N-acetylglucosamine-6-phosphate deacetylase, 2-amino-2-deoxy-6-O-phosphono-alpha-D-glucopyranose, ZINC ION, ... (4 entities in total)
• Functional Keywords: n-acetylglucosamine-6-phosphate deacetylase, naga, amidohydrolase domain-containing protein 2, amdhd2, hydrolase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 88256.70

Authors

Ruegenberg, S.,Kroef, V.,Baumann, U.,Denzel, M.S. (deposition date: 2021-03-14, release date: 2021-04-28, Last modification date: 2024-01-31)

• Primary citation: Kroef, V.,Ruegenberg, S.,Horn, M.,Allmeroth, K.,Ebert, L.,Bozkus, S.,Miethe, S.,Elling, U.,Schermer, B.,Baumann, U.,Denzel, M.S.; GFPT2/GFAT2 and AMDHD2 act in tandem to control the hexosamine pathway.; Elife, 11:-, 2022; PubMed: 35229715; DOI: 10.7554/eLife.69223

Experimental method

X-RAY DIFFRACTION (1.898 Å)