7NUT

Crystal structure of human AMDHD2 in complex with Zn and GlcN6P

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005634	cellular_component	nucleus
A	0005829	cellular_component	cytosol
A	0006044	biological_process	N-acetylglucosamine metabolic process
A	0006046	biological_process	N-acetylglucosamine catabolic process
A	0006048	biological_process	UDP-N-acetylglucosamine biosynthetic process
A	0008448	molecular_function	N-acetylglucosamine-6-phosphate deacetylase activity
A	0016787	molecular_function	hydrolase activity
A	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
A	0019262	biological_process	N-acetylneuraminate catabolic process
A	0046872	molecular_function	metal ion binding
A	0047419	molecular_function	N-acetylgalactosamine-6-phosphate deacetylase activity
A	0106279	biological_process	negative regulation of UDP-N-acetylglucosamine biosynthetic process
B	0005634	cellular_component	nucleus
B	0005829	cellular_component	cytosol
B	0006044	biological_process	N-acetylglucosamine metabolic process
B	0006046	biological_process	N-acetylglucosamine catabolic process
B	0006048	biological_process	UDP-N-acetylglucosamine biosynthetic process
B	0008448	molecular_function	N-acetylglucosamine-6-phosphate deacetylase activity
B	0016787	molecular_function	hydrolase activity
B	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
B	0019262	biological_process	N-acetylneuraminate catabolic process
B	0046872	molecular_function	metal ion binding
B	0047419	molecular_function	N-acetylgalactosamine-6-phosphate deacetylase activity
B	0106279	biological_process	negative regulation of UDP-N-acetylglucosamine biosynthetic process

Functional Information from PROSITE/UniProt

site_id	PS00501
Number of Residues	8
Details	SPASE_I_1 Signal peptidases I serine active site. GCSMESAL

Chain	Residue	Details
A	GLY347-LEU354

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"UniProtKB","id":"P0AF18","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	22
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P0AF18","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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