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3E9P
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BU of 3e9p by Molmil
Crystal Structure of Yeast Prp8, Residues 1827-2092
Descriptor: Pre-mRNA-splicing factor 8
Authors:Pena, V, Rozov, A, Wahl, M.C.
Deposit date:2008-08-22
Release date:2008-10-07
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure and function of an RNase H domain at the heart of the spliceosome.
Embo J., 27, 2008
6NIT
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BU of 6nit by Molmil
Human Argonaute2-miR-122 bound to a target RNA with four central mismatches (bu4)
Descriptor: Protein argonaute-2, RNA (5'-R(P*AP*AP*CP*AP*CP*CP*AP*UP*CP*CP*AP*AP*CP*AP*CP*UP*CP*CP*AP*AP*A)-3'), RNA (5'-R(P*UP*GP*GP*AP*GP*UP*GP*UP*GP*AP*CP*AP*AP*UP*GP*GP*UP*GP*UP*UP*U)-3')
Authors:Sheu-Gruttadauria, J, MacRae, I.J.
Deposit date:2018-12-31
Release date:2019-08-07
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structural Basis for Target-Directed MicroRNA Degradation.
Mol.Cell, 75, 2019
6MDZ
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BU of 6mdz by Molmil
Human Argonaute2-miR-122 bound to a target RNA with two central mismatches (bu2)
Descriptor: PHENOL, Protein argonaute-2, RNA (5'-R(P*AP*AP*AP*CP*AP*CP*CP*AP*UP*UP*UP*CP*CP*AP*CP*AP*CP*UP*CP*CP*AP*AP*A)-3'), ...
Authors:Sheu-Gruttadauria, J, MacRae, I.J.
Deposit date:2018-09-05
Release date:2019-08-07
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural Basis for Target-Directed MicroRNA Degradation.
Mol.Cell, 75, 2019
6MFR
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BU of 6mfr by Molmil
Human Argonaute2-miR-122 bound to a target RNA with three central mismatches (bu3)
Descriptor: PHENOL, PHOSPHATE ION, Protein argonaute-2, ...
Authors:Sheu-Gruttadauria, J, MacRae, I.J.
Deposit date:2018-09-12
Release date:2019-08-07
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structural Basis for Target-Directed MicroRNA Degradation.
Mol.Cell, 75, 2019
6MFN
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BU of 6mfn by Molmil
Human Argonaute2-miR-27a bound to HSUR1 target RNA
Descriptor: PHENOL, Protein argonaute-2, RNA (5'-R(P*UP*CP*UP*GP*UP*GP*AP*UP*AP*A)-3'), ...
Authors:Sheu-Gruttadauria, J, MacRae, I.J.
Deposit date:2018-09-11
Release date:2019-08-07
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis for Target-Directed MicroRNA Degradation.
Mol.Cell, 75, 2019
8VAJ
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BU of 8vaj by Molmil
Human Argonaute3 bound to cityRNA and target RNA
Descriptor: Protein argonaute-3, RNA (5'-R(P*(SRA)P*AP*GP*CP*AP*CP*UP*UP*UP*AP*AP*A)-3'), RNA (5'-R(P*UP*AP*AP*AP*GP*UP*GP*CP*UP*UP*AP*G)-3')
Authors:Zhang, H, Sim, G, Adhav, V.A, Nakanishi, K.
Deposit date:2023-12-11
Release date:2024-10-16
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:Target cleavage and gene silencing by Argonautes with cityRNAs.
Cell Rep, 43, 2024
2CZJ
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BU of 2czj by Molmil
Crystal structure of the tRNA domain of tmRNA from Thermus thermophilus HB8
Descriptor: SsrA-binding protein, tmRNA (63-MER)
Authors:Bessho, Y, Shibata, R, Sekine, S, Murayama, K, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-07-13
Release date:2006-10-31
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Structural basis for functional mimicry of long-variable-arm tRNA by transfer-messenger RNA.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2NUF
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BU of 2nuf by Molmil
Crystal structure of RNase III from Aquifex aeolicus complexed with ds-RNA at 2.5-Angstrom Resolution
Descriptor: 28-MER, MAGNESIUM ION, Ribonuclease III
Authors:Gan, J.H, Shaw, G, Tropea, J.E, Waugh, D.S, Court, D.L, Ji, X.
Deposit date:2006-11-09
Release date:2007-11-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A stepwise model for double-stranded RNA processing by ribonuclease III.
Mol.Microbiol., 67, 2007
8VU0
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BU of 8vu0 by Molmil
Co-crystal structure of Aquifex aeolicus Trbp111 in complex with E. coli tRNA-Ile
Descriptor: Methionyl-tRNA synthetase beta subunit, RNA (76-MER)
Authors:Umuhire Juru, A, Zhang, J.
Deposit date:2024-01-27
Release date:2024-08-07
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Structural basis of tRNA recognition by the widespread OB fold.
Nat Commun, 15, 2024
2NUG
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BU of 2nug by Molmil
Crystal structure of RNase III from Aquifex aeolicus complexed with ds-RNA at 1.7-Angstrom Resolution
Descriptor: 5'-R(P*AP*AP*GP*GP*UP*CP*AP*UP*UP*CP*G)-3', 5'-R(P*AP*GP*UP*GP*GP*CP*CP*UP*UP*GP*C)-3', MAGNESIUM ION, ...
Authors:Gan, J.H, Shaw, G, Tropea, J.E, Waugh, D.S, Court, D.L, Ji, X.
Deposit date:2006-11-09
Release date:2007-11-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A stepwise model for double-stranded RNA processing by ribonuclease III.
Mol.Microbiol., 67, 2007
2NUE
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BU of 2nue by Molmil
Crystal structure of RNase III from Aquifex aeolicus complexed with ds-RNA at 2.9-Angstrom Resolution
Descriptor: 46-MER, Ribonuclease III
Authors:Gan, J.H, Shaw, G, Tropea, J.E, Waugh, D.S, Court, D.L, Ji, X.
Deposit date:2006-11-09
Release date:2007-11-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A stepwise model for double-stranded RNA processing by ribonuclease III.
Mol.Microbiol., 67, 2007
8CDP
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BU of 8cdp by Molmil
Cryo-EM structure of the RESC1-RESC2 complex
Descriptor: Guide_RNA_associated_protein_-_putative, Mitochondrial guide RNA binding complex subunit 2
Authors:Dolce, L.G, Weis, F, Kowalinski, E.
Deposit date:2023-01-31
Release date:2023-03-29
Last modified:2025-07-09
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis for guide RNA selection by the RESC1-RESC2 complex.
Nucleic Acids Res., 51, 2023
4U37
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BU of 4u37 by Molmil
Native 7mer-RNA duplex
Descriptor: RNA (5'-R(*GP*GP*AP*GP*CP*UP*A)-3'), RNA (5'-R(*UP*AP*GP*CP*UP*CP*C)-3')
Authors:Sheng, J, Larsen, A, Heuberger, B, Blain, J.C, Szostak, J.W.
Deposit date:2014-07-18
Release date:2014-08-13
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal Structure Studies of RNA Duplexes Containing s(2)U:A and s(2)U:U Base Pairs.
J.Am.Chem.Soc., 136, 2014
4A3I
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BU of 4a3i by Molmil
RNA Polymerase II binary complex with DNA
Descriptor: 5'-D(*GP*GP*CP*AP*CP*AP*AP*CP*TP*GP*CP*GP*GP*CP*T)-3', DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, ...
Authors:Cheung, A.C.M, Sainsbury, S, Cramer, P.
Deposit date:2011-09-30
Release date:2012-02-08
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structural basis of initial RNA polymerase II transcription.
EMBO J., 30, 2011
4V34
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BU of 4v34 by Molmil
The Structure of A-PGS from Pseudomonas aeruginosa (SeMet derivative)
Descriptor: ALANYL-TRNA-DEPENDENT L-ALANYL- PHOPHATIDYLGLYCEROL SYNTHASE, CHLORIDE ION, SULFATE ION
Authors:Krausze, J, Hebecker, S, Hasenkampf, T, Heinz, D.W, Moser, J.
Deposit date:2014-10-16
Release date:2015-08-19
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structures of Two Bacterial Resistance Factors Mediating tRNA-Dependent Aminoacylation of Phosphatidylglycerol with Lysine or Alanine.
Proc.Natl.Acad.Sci.USA, 112, 2015
5M59
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BU of 5m59 by Molmil
Crystal structure of Chaetomium thermophilum Brr2 helicase core in complex with Prp8 Jab1 domain
Descriptor: ACETATE ION, Pre-mRNA splicing helicase-like protein, Putative pre-mRNA splicing factor
Authors:Absmeier, E, Becke, C, Wollenhaupt, J, Santos, K.F, Wahl, M.C.
Deposit date:2016-10-20
Release date:2016-12-21
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Interplay of cis- and trans-regulatory mechanisms in the spliceosomal RNA helicase Brr2.
Cell Cycle, 16, 2017
8TG5
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BU of 8tg5 by Molmil
tRNA 2'-phosphotransferase (Tpt1) from Pyrococcus horikoshii in complex with branched 2'-PO4 RNA
Descriptor: (2S,3R,4R,5S)-2-(6-amino-9H-purin-9-yl)-4-{[(S)-{[(2R,3S,4R,5S)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl]oxy}-5-({[(S)-{[(2R,3R,4S,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]oxy}(hydroxy)phosphoryl]oxy}methyl)oxolan-3-yl dihydrogen phosphate (non-preferred name), CHLORIDE ION, POTASSIUM ION, ...
Authors:Jacewicz, A, Dantuluri, S, Shuman, S.
Deposit date:2023-07-12
Release date:2024-06-05
Last modified:2024-06-26
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for Tpt1-catalyzed 2'-PO 4 transfer from RNA and NADP(H) to NAD.
Proc.Natl.Acad.Sci.USA, 120, 2023
1I6H
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BU of 1i6h by Molmil
RNA POLYMERASE II ELONGATION COMPLEX
Descriptor: 5'-D(P*AP*AP*AP*TP*GP*CP*CP*TP*GP*GP*TP*CP*T)-3', 5'-R(P*GP*AP*CP*CP*AP*GP*GP*CP*A)-3', DNA-DIRECTED RNA POLYMERASE II 13.6KD POLYPEPTIDE, ...
Authors:Gnatt, A.L, Cramer, P, Kornberg, R.D.
Deposit date:2001-03-02
Release date:2001-04-23
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural basis of transcription: an RNA polymerase II elongation complex at 3.3 A resolution.
Science, 292, 2001
7W0A
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BU of 7w0a by Molmil
dmDicer2-LoqsPD-dsRNA Dimer status
Descriptor: Dicer-2, isoform A, Loquacious, ...
Authors:Su, S, Wang, J, Wang, H.W, Ma, J.
Deposit date:2021-11-18
Release date:2022-04-27
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.12 Å)
Cite:Structural insights into dsRNA processing by Drosophila Dicer-2-Loqs-PD.
Nature, 607, 2022
8TG4
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BU of 8tg4 by Molmil
tRNA 2'-phosphotransferase (Tpt1) from Aeropyrum pernix in complex with ADP-ribose-2"-phosphate and 2'-OH RNA
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, NITRATE ION, ...
Authors:Jacewicz, A, Dantuluri, S, Shuman, S.
Deposit date:2023-07-12
Release date:2023-11-08
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:Structural basis for Tpt1-catalyzed 2'-PO 4 transfer from RNA and NADP(H) to NAD.
Proc.Natl.Acad.Sci.USA, 120, 2023
7W0C
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BU of 7w0c by Molmil
Dicer2-Loqs-PD-dsRNA complex at early-translocation state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Dicer-2, isoform A, ...
Authors:Su, S, Wang, J, Wang, H.W, Ma, J.
Deposit date:2021-11-18
Release date:2022-04-27
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.93 Å)
Cite:Structural insights into dsRNA processing by Drosophila Dicer-2-Loqs-PD.
Nature, 607, 2022
7ZNK
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BU of 7znk by Molmil
Structure of an endogenous human TREX complex bound to mRNA
Descriptor: RNA, Spliceosome RNA helicase DDX39B, THO complex subunit 1, ...
Authors:Pacheco-Fiallos, F.B, Vorlaender, M.K, Plaschka, C.
Deposit date:2022-04-21
Release date:2023-05-03
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:mRNA recognition and packaging by the human transcription-export complex.
Nature, 616, 2023
7F3E
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BU of 7f3e by Molmil
Cryo-EM structure of the minimal protein-only RNase P from Aquifex aeolicus
Descriptor: RNA-free ribonuclease P
Authors:Teramoto, T, Koyasu, T, Adachi, N, Kawasaki, M, Moriya, T, Numata, T, Senda, T, Kakuta, Y.
Deposit date:2021-06-16
Release date:2021-08-11
Last modified:2025-06-25
Method:ELECTRON MICROSCOPY (3.62 Å)
Cite:Minimal protein-only RNase P structure reveals insights into tRNA precursor recognition and catalysis.
J.Biol.Chem., 297, 2021
7W0D
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BU of 7w0d by Molmil
Dicer2-LoqsPD-dsRNA complex at mid-translocation state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Dicer-2, isoform A, ...
Authors:Su, S, Wang, J, Wang, H.W, Ma, J.
Deposit date:2021-11-18
Release date:2022-04-27
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (4.18 Å)
Cite:Structural insights into dsRNA processing by Drosophila Dicer-2-Loqs-PD.
Nature, 607, 2022
8IDF
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BU of 8idf by Molmil
Crystal structure of human TUT1 complexed with U6 snRNA
Descriptor: RNA (53-MER), Speckle targeted PIP5K1A-regulated poly(A) polymerase, ZINC ION
Authors:Yamashita, S, Tomita, K.
Deposit date:2023-02-13
Release date:2023-08-09
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Mechanism of U6 snRNA oligouridylation by human TUT1.
Nat Commun, 14, 2023

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