8TG5
tRNA 2'-phosphotransferase (Tpt1) from Pyrococcus horikoshii in complex with branched 2'-PO4 RNA
Summary for 8TG5
Entry DOI | 10.2210/pdb8tg5/pdb |
Related | 8TFI |
Descriptor | Probable RNA 2'-phosphotransferase, (2S,3R,4R,5S)-2-(6-amino-9H-purin-9-yl)-4-{[(S)-{[(2R,3S,4R,5S)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl]oxy}-5-({[(S)-{[(2R,3R,4S,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]oxy}(hydroxy)phosphoryl]oxy}methyl)oxolan-3-yl dihydrogen phosphate (non-preferred name), POTASSIUM ION, ... (5 entities in total) |
Functional Keywords | trna 2'-phosphotransferase, tpt1, trna splicing, branched rna, 2'-po4 rna, transferase |
Biological source | Pyrococcus horikoshii OT3 |
Total number of polymer chains | 1 |
Total formula weight | 22029.40 |
Authors | Jacewicz, A.,Dantuluri, S.,Shuman, S. (deposition date: 2023-07-12, release date: 2024-06-05, Last modification date: 2024-06-26) |
Primary citation | Jacewicz, A.,Dantuluri, S.,Shuman, S. Structural basis for Tpt1-catalyzed 2'-PO 4 transfer from RNA and NADP(H) to NAD. Proc.Natl.Acad.Sci.USA, 120:e2312999120-e2312999120, 2023 Cited by PubMed: 37883434DOI: 10.1073/pnas.2312999120 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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