5M59

Crystal structure of Chaetomium thermophilum Brr2 helicase core in complex with Prp8 Jab1 domain

Summary for 5M59

Entry DOI	10.2210/pdb5m59/pdb
Descriptor	Putative pre-mRNA splicing factor, Pre-mRNA splicing helicase-like protein, ACETATE ION, ... (4 entities in total)
Functional Keywords	brr2, pre-mrna splicing, rna-helicase, prp8, splicing
Biological source	Chaetomium thermophilum More
Total number of polymer chains	8
Total formula weight	931294.44
Authors	Absmeier, E.,Becke, C.,Wollenhaupt, J.,Santos, K.F.,Wahl, M.C. (deposition date: 2016-10-20, release date: 2016-12-21, Last modification date: 2024-01-17)
Primary citation	Absmeier, E.,Becke, C.,Wollenhaupt, J.,Santos, K.F.,Wahl, M.C. Interplay of cis- and trans-regulatory mechanisms in the spliceosomal RNA helicase Brr2. Cell Cycle, 16:100-112, 2017 Cited by PubMed: 27880071 DOI: 10.1080/15384101.2016.1255384 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.2 Å)

Structure validation