5M59

Crystal structure of Chaetomium thermophilum Brr2 helicase core in complex with Prp8 Jab1 domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	B, D, F, H	Putative pre-mRNA splicing factor	polymer	276	31083.3	4	UniProt (G0SFL3) Pfam (PF08084) In PDB	Chaetomium thermophilum
2	A, C, E, G	Pre-mRNA splicing helicase-like protein	polymer	1772	201681.3	4	UniProt (G0S0B9) Pfam (PF00270) Pfam (PF00271) Pfam (PF02889) In PDB	Chaetomium thermophilum
3	A, C, E, G	ACETATE ION	non-polymer		59.0	4	Chemie (ACT)
4		water	water		18.0	30	Chemie (HOH)

Sequence modifications

B, D, F, H: 2037 - 2309 (UniProt: G0SFL3)

PDB	External Database	Details
Gly 2034	-	expression tag
Ala 2035	-	expression tag
Met 2036	-	expression tag

A, C, E, G: 426 - 2193 (UniProt: G0S0B9)

PDB	External Database	Details
Gly 422	-	expression tag
Ala 423	-	expression tag
Glu 424	-	expression tag
Phe 425	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	931058.3
Non-Polymers*	Number of molecules	4
	Total formula weight	236.2
All*	Total formula weight	931294.4

*Water molecules are not included.