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5M59

Crystal structure of Chaetomium thermophilum Brr2 helicase core in complex with Prp8 Jab1 domain

Functional Information from GO Data
ChainGOidnamespacecontents
A0003676molecular_functionnucleic acid binding
A0005524molecular_functionATP binding
A0016887molecular_functionATP hydrolysis activity
B0000398biological_processmRNA splicing, via spliceosome
B0005681cellular_componentspliceosomal complex
B0008233molecular_functionpeptidase activity
B0008237molecular_functionmetallopeptidase activity
C0003676molecular_functionnucleic acid binding
C0005524molecular_functionATP binding
C0016887molecular_functionATP hydrolysis activity
D0000398biological_processmRNA splicing, via spliceosome
D0005681cellular_componentspliceosomal complex
D0008233molecular_functionpeptidase activity
D0008237molecular_functionmetallopeptidase activity
E0003676molecular_functionnucleic acid binding
E0005524molecular_functionATP binding
E0016887molecular_functionATP hydrolysis activity
F0000398biological_processmRNA splicing, via spliceosome
F0005681cellular_componentspliceosomal complex
F0008233molecular_functionpeptidase activity
F0008237molecular_functionmetallopeptidase activity
G0003676molecular_functionnucleic acid binding
G0005524molecular_functionATP binding
G0016887molecular_functionATP hydrolysis activity
H0000398biological_processmRNA splicing, via spliceosome
H0005681cellular_componentspliceosomal complex
H0008233molecular_functionpeptidase activity
H0008237molecular_functionmetallopeptidase activity
Functional Information from PDB Data
site_idAC1
Number of Residues5
Detailsbinding site for residue ACT A 2201
ChainResidue
AGLY554
ASER555
AGLY556
ALYS557
ATHR558

site_idAC2
Number of Residues3
Detailsbinding site for residue ACT C 2201
ChainResidue
CGLY556
CLYS557
CTHR558

site_idAC3
Number of Residues5
Detailsbinding site for residue ACT E 2201
ChainResidue
EGLY554
ESER555
EGLY556
ELYS557
ETHR553

site_idAC4
Number of Residues5
Detailsbinding site for residue ACT G 2201
ChainResidue
GGLY554
GSER555
GGLY556
GLYS557
GTHR558

224201

PDB entries from 2024-08-28

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