5GTC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5gtc by Molmil](/molmil-images/mine/5gtc) | Crystal structure of complex between DMAP-SH conjugated with a Kaposi's sarcoma herpesvirus LANA peptide (5-15) and nucleosome core particle | Descriptor: | CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ... | Authors: | Arimura, Y, Kato, D, Suto, H, Kurumizaka, H, Kawashima, S.A, Yamatsugu, K, Kanai, M. | Deposit date: | 2016-08-19 | Release date: | 2017-06-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Synthetic Posttranslational Modifications: Chemical Catalyst-Driven Regioselective Histone Acylation of Native Chromatin. J. Am. Chem. Soc., 139, 2017
|
|
2ATF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2atf by Molmil](/molmil-images/mine/2atf) | X-RAY STRUCTURE OF cysteine dioxygenase type I FROM MUS MUSCULUS MM.241056 | Descriptor: | 1,2-ETHANEDIOL, Cysteine dioxygenase type I, NICKEL (II) ION | Authors: | Wesenberg, G.E, Phillips Jr, G.N, Mccoy, J.G, Bitto, E, Bingman, C.A, Allard, S.T.M, Center for Eukaryotic Structural Genomics (CESG) | Deposit date: | 2005-08-24 | Release date: | 2005-10-18 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structure and mechanism of mouse cysteine dioxygenase. Proc.Natl.Acad.Sci.Usa, 103, 2006
|
|
1WXX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1wxx by Molmil](/molmil-images/mine/1wxx) | Crystal structure of Tt1595, a putative SAM-dependent methyltransferase from Thermus thermophillus HB8 | Descriptor: | PHOSPHATE ION, POTASSIUM ION, hypothetical protein TTHA1280 | Authors: | Pioszak, A.A, Murayama, K, Nakagawa, N, Ebihara, A, Kuramitsu, S, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-02-02 | Release date: | 2005-08-02 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structures of a putative RNA 5-methyluridine methyltransferase, Thermus thermophilus TTHA1280, and its complex with S-adenosyl-L-homocysteine. Acta Crystallogr.,Sect.F, 61, 2005
|
|
5JTQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5jtq by Molmil](/molmil-images/mine/5jtq) | The structure of chaperone SecB in complex with unstructured MBP binding site d | Descriptor: | Maltose-binding periplasmic protein, Protein-export protein SecB | Authors: | Huang, C, Saio, T, Rossi, P, Kalodimos, C.G. | Deposit date: | 2016-05-09 | Release date: | 2016-08-24 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structural basis for the antifolding activity of a molecular chaperone. Nature, 537, 2016
|
|
1HB7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1hb7 by Molmil](/molmil-images/mine/1hb7) | quasi-atomic resolution model of bacteriophage PRD1 sus1 mutant, obtained by combined cryo-EM and X-ray crystallography. | Descriptor: | BACTERIOPHAGE PRD1 SUS1 MUTANT CAPSID | Authors: | San Martin, C, Burnett, R.M, De Haas, F, Heinkel, R, Rutten, T, Fuller, S.D, Butcher, S.J, Bamford, D.H. | Deposit date: | 2001-04-12 | Release date: | 2001-12-05 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (14 Å) | Cite: | Combined Em/X-Ray Imaging Yields a Quasi-Atomic Model of the Adenovirus-Related Bacteriophage Prd1 and Shows Key Capsid and Membrane Interactions. Structure, 9, 2001
|
|
3L5N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3l5n by Molmil](/molmil-images/mine/3l5n) | |
3L9H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3l9h by Molmil](/molmil-images/mine/3l9h) | X-ray structure of mitotic kinesin-5 (KSP, KIF11, Eg5)in complex with the hexahydro-2H-pyrano[3,2-c]quinoline EMD 534085 | Descriptor: | 1-[2-(dimethylamino)ethyl]-3-{[(2R,4aS,5R,10bS)-5-phenyl-9-(trifluoromethyl)-3,4,4a,5,6,10b-hexahydro-2H-pyrano[3,2-c]quinolin-2-yl]methyl}urea, ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein KIF11 | Authors: | Knoechel, T. | Deposit date: | 2010-01-05 | Release date: | 2010-03-02 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The discovery and optimization of hexahydro-2H-pyrano[3,2-c]quinolines (HHPQs) as potent and selective inhibitors of the mitotic kinesin-5. Bioorg.Med.Chem.Lett., 20, 2010
|
|
5JZT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5jzt by Molmil](/molmil-images/mine/5jzt) | |
6X7I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6x7i by Molmil](/molmil-images/mine/6x7i) | |
8E0H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8e0h by Molmil](/molmil-images/mine/8e0h) | Crystal structure of human Sar1aD104/D140A double mutant | Descriptor: | GTP-binding protein SAR1a, GUANOSINE-5',3'-TETRAPHOSPHATE | Authors: | Huang, Q. | Deposit date: | 2022-08-09 | Release date: | 2022-11-30 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The alarmone ppGpp selectively inhibits the isoform A of the human small GTPase Sar1. Proteins, 91, 2023
|
|
5GZR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5gzr by Molmil](/molmil-images/mine/5gzr) | Zika virus E protein complexed with a neutralizing antibody Z23-Fab | Descriptor: | Z23 Fab heavy chain, Z23 Fab light chain, structural protein E, ... | Authors: | Gao, G.G, Shi, Y, Peng, R, Liu, S. | Deposit date: | 2016-10-01 | Release date: | 2016-11-30 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (9.4 Å) | Cite: | Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus Sci Transl Med, 8, 2016
|
|
3LEL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3lel by Molmil](/molmil-images/mine/3lel) | Structural Insight into the Sequence-Dependence of Nucleosome Positioning | Descriptor: | 147-MER DNA, Histone H2A, Histone H2B 1.1, ... | Authors: | Wu, B, Vasudevan, D, Davey, C.A. | Deposit date: | 2010-01-15 | Release date: | 2010-05-19 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Structural insight into the sequence dependence of nucleosome positioning Structure, 18, 2010
|
|
1GU6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1gu6 by Molmil](/molmil-images/mine/1gu6) | Structure of the Periplasmic Cytochrome c Nitrite Reductase from Escherichia coli | Descriptor: | CALCIUM ION, CYTOCHROME C552, GLYCEROL, ... | Authors: | Bamford, V.A, Angove, H.C, Seward, H.E, Thomson, A.J, Cole, J.A, Butt, J.N, Hemmings, A.M, Richardson, D.J. | Deposit date: | 2002-01-24 | Release date: | 2002-03-08 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure and Spectroscopy of the Periplasmic Cytochrome C Nitrite Reductase from Escherichia Coli Biochemistry, 41, 2002
|
|
5G6U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5g6u by Molmil](/molmil-images/mine/5g6u) | Crystal structure of langerin carbohydrate recognition domain with GlcNS6S | Descriptor: | 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ... | Authors: | Porkolab, V, Chabrol, E, Varga, N, Ordanini, S, Sutkeviciute, I, Thepaut, M, Bernardi, A, Fieschi, F. | Deposit date: | 2016-07-21 | Release date: | 2018-02-21 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.844 Å) | Cite: | Rational-Differential Design of Highly Specific Glycomimetic Ligands: Targeting DC-SIGN and Excluding Langerin Recognition. ACS Chem. Biol., 13, 2018
|
|
5MFV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5mfv by Molmil](/molmil-images/mine/5mfv) | Crystal structure of the GluK1 ligand-binding domain in complex with kainate and BPAM-521 at 2.18 A resolution | Descriptor: | 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, 4-Cyclopropyl-3,4-dihydro-7-hydroxy-2H-1,2,4-benzothiadiazine 1,1-dioxide, ACETATE ION, ... | Authors: | Larsen, A.P, Frydenvang, K, Kastrup, J.S. | Deposit date: | 2016-11-18 | Release date: | 2017-04-12 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.181 Å) | Cite: | Identification and Structure-Function Study of Positive Allosteric Modulators of Kainate Receptors. Mol. Pharmacol., 91, 2017
|
|
2X02
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2x02 by Molmil](/molmil-images/mine/2x02) | CRYSTAL STRUCTURE OF THE CLASS D BETA-LACTAMASE OXA-10 AT 1.35 A RESOLUTION | Descriptor: | BETA-LACTAMASE OXA-10, DIMETHYL SULFOXIDE, GLYCEROL, ... | Authors: | Vercheval, L, Kerff, F, Sauvage, E, Herman, R, Galleni, M, Charlier, P. | Deposit date: | 2009-12-04 | Release date: | 2010-12-08 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Impact of the Carboxylated Lysine on the Acylation and Deacylation Step in Class D Beta-Lactamase To be Published
|
|
5GJJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5gjj by Molmil](/molmil-images/mine/5gjj) | |
5KDL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5kdl by Molmil](/molmil-images/mine/5kdl) | Crystal structure of the 4 alanine insertion variant of the Gi alpha1 subunit bound to GTPgammaS | Descriptor: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Guanine nucleotide-binding protein G(i) subunit alpha-1, MAGNESIUM ION | Authors: | Kaya, A.I, Lokits, A.D, Gilbert, J, Iverson, T.M, Meiler, J, Hamm, H.E. | Deposit date: | 2016-06-08 | Release date: | 2016-08-03 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.665 Å) | Cite: | A Conserved Hydrophobic Core in G alpha i1 Regulates G Protein Activation and Release from Activated Receptor. J.Biol.Chem., 291, 2016
|
|
8AYQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ayq by Molmil](/molmil-images/mine/8ayq) | NaK C-DI mutant with Rb+ and Ca2+ | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, CHLORIDE ION, ... | Authors: | Minniberger, S, Plested, A.J.R. | Deposit date: | 2022-09-02 | Release date: | 2023-02-22 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Mechanism of Calcium Permeation in a Glutamate Receptor Ion Channel. J.Chem.Inf.Model., 63, 2023
|
|
6RNY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6rny by Molmil](/molmil-images/mine/6rny) | PFV intasome - nucleosome strand transfer complex | Descriptor: | DNA (108-MER), DNA (128-MER), DNA (33-MER), ... | Authors: | Pye, V.E, Renault, L, Maskell, D.P, Cherepanov, P, Costa, A. | Deposit date: | 2019-05-09 | Release date: | 2019-09-25 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Retroviral integration into nucleosomes through DNA looping and sliding along the histone octamer. Nat Commun, 10, 2019
|
|
2B0Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2b0z by Molmil](/molmil-images/mine/2b0z) | |
8AYP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ayp by Molmil](/molmil-images/mine/8ayp) | NaK C-DI mutant with Rb+ and Ba2+ | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, BARIUM ION, Potassium channel protein, ... | Authors: | Minniberger, S, Plested, A.J.R. | Deposit date: | 2022-09-02 | Release date: | 2023-02-22 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Mechanism of Calcium Permeation in a Glutamate Receptor Ion Channel. J.Chem.Inf.Model., 63, 2023
|
|
5KGZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5kgz by Molmil](/molmil-images/mine/5kgz) | Phenol-soluble modulin Beta2 | Descriptor: | Modulin Beta2 | Authors: | Towle, K.M, Lohans, C.T, Acedo, J.Z, Van Belkum, M.J, Miskolzie, M, Vederas, J.C. | Deposit date: | 2016-06-13 | Release date: | 2016-08-31 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution Structures of Phenol-Soluble Modulins alpha 1, alpha 3, and beta 2, Virulence Factors from Staphylococcus aureus. Biochemistry, 55, 2016
|
|
7QZO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7qzo by Molmil](/molmil-images/mine/7qzo) | Crystal structure of GacS D1 domain | Descriptor: | CADMIUM ION, GLYCEROL, Histidine kinase | Authors: | Fadel, F, Bassim, V, Botzanowski, T, Francis, V.I, Legrand, P, Porter, S.L, Bourne, Y, Cianferani, S, Vincent, F. | Deposit date: | 2022-01-31 | Release date: | 2022-07-06 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Insights into the atypical autokinase activity of the Pseudomonas aeruginosa GacS histidine kinase and its interaction with RetS. Structure, 30, 2022
|
|
3UO5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3uo5 by Molmil](/molmil-images/mine/3uo5) | Aurora A in complex with YL1-038-31 | Descriptor: | 4-{[4-(phenylamino)pyrimidin-2-yl]amino}benzoic acid, Serine/Threonine-Protein Kinase 6 | Authors: | Martin, M.P, Zhu, J.-Y, Schonbrunn, E. | Deposit date: | 2011-11-16 | Release date: | 2012-01-25 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.7012 Å) | Cite: | A Novel Mechanism by Which Small Molecule Inhibitors Induce the DFG Flip in Aurora A. Acs Chem.Biol., 7, 2012
|
|