8E0H

Crystal structure of human Sar1aD104/D140A double mutant

Summary for 8E0H

Entry DOI	10.2210/pdb8e0h/pdb
Related	8DZM
Descriptor	GTP-binding protein SAR1a, GUANOSINE-5',3'-TETRAPHOSPHATE (3 entities in total)
Functional Keywords	sar1a, ppgpp, copii, small gtpase, signaling protein
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	45815.83
Authors	Huang, Q. (deposition date: 2022-08-09, release date: 2022-11-30, Last modification date: 2023-10-25)
Primary citation	Huang, Q.,Szebenyi, D.M.E. The alarmone ppGpp selectively inhibits the isoform A of the human small GTPase Sar1. Proteins, 91:518-531, 2023 Cited by PubMed: 36369712 DOI: 10.1002/prot.26445 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation