8DZM
Crystal structure of human Sar1a in complex with ppGpp and Magnesium
Summary for 8DZM
Entry DOI | 10.2210/pdb8dzm/pdb |
Descriptor | GTP-binding protein SAR1a, MAGNESIUM ION, GUANOSINE-5',3'-TETRAPHOSPHATE, ... (4 entities in total) |
Functional Keywords | sar1a, ppgpp, copii, small gtpase, signaling protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 46089.09 |
Authors | Huang, Q. (deposition date: 2022-08-08, release date: 2023-08-16, Last modification date: 2024-02-28) |
Primary citation | Huang, Q.,Szebenyi, D.M.E. The alarmone ppGpp selectively inhibits the isoform A of the human small GTPase Sar1. Proteins, 91:518-531, 2023 Cited by PubMed: 36369712DOI: 10.1002/prot.26445 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.648 Å) |
Structure validation
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