5G6U
Crystal structure of langerin carbohydrate recognition domain with GlcNS6S
Summary for 5G6U
Entry DOI | 10.2210/pdb5g6u/pdb |
Descriptor | LANGERIN, TRYPTOPHAN, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, ... (7 entities in total) |
Functional Keywords | carbohydrate binding protein, langerin, cd207, clec4k, c-type lectins, clrs, sulfated carbohydrates |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Membrane ; Single-pass type II membrane protein : Q9UJ71 |
Total number of polymer chains | 4 |
Total formula weight | 121328.70 |
Authors | Porkolab, V.,Chabrol, E.,Varga, N.,Ordanini, S.,Sutkeviciute, I.,Thepaut, M.,Bernardi, A.,Fieschi, F. (deposition date: 2016-07-21, release date: 2018-02-21, Last modification date: 2024-01-10) |
Primary citation | Porkolab, V.,Chabrol, E.,Varga, N.,Ordanini, S.,Sutkeviciu Te, I.,Thepaut, M.,Garcia-Jimenez, M.J.,Girard, E.,Nieto, P.M.,Bernardi, A.,Fieschi, F. Rational-Differential Design of Highly Specific Glycomimetic Ligands: Targeting DC-SIGN and Excluding Langerin Recognition. ACS Chem. Biol., 13:600-608, 2018 Cited by PubMed: 29272097DOI: 10.1021/acschembio.7b00958 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.844 Å) |
Structure validation
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