PDB: 8717 resultsInfo pagesStatus searchChemie searchBIRD

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7QWQ	Ternary complex of ribosome nascent chain with SRP and NAC Descriptor: 28S rRNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... Authors: Jomaa, A, Gamerdinger, M, Hsieh, H, Wallisch, A, Chandrasekaran, V, Ulusoy, Z, Scaiola, A, Hegde, R, Shan, S, Ban, N, Deuerling, E. Deposit date: 2022-01-25 Release date: 2022-03-16 Last modified: 2024-07-17 Method: ELECTRON MICROSCOPY (2.83 Å) Cite: Mechanism of signal sequence handover from NAC to SRP on ribosomes during ER-protein targeting. Science, 375, 2022
8P2K	Ternary complex of translating ribosome, NAC and METAP1 Descriptor: 18s rRNA, 28S rRNA, 40S ribosomal protein S11, ... Authors: Jia, M, Jaskolowski, M, Scaiola, A, Jomaa, A, Ban, N. Deposit date: 2023-05-16 Release date: 2023-07-19 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: NAC controls cotranslational N-terminal methionine excision in eukaryotes. Science, 380, 2023
7W59	The cryo-EM structure of human pre-C*-I complex Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... Authors: Zhan, X, Lu, Y, Shi, Y. Deposit date: 2021-11-29 Release date: 2022-06-22 Last modified: 2022-08-17 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Mechanism of exon ligation by human spliceosome. Mol.Cell, 82, 2022
6ICZ	Cryo-EM structure of a human post-catalytic spliceosome (P complex) at 3.0 angstrom Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... Authors: Zhang, X, Zhan, X, Yan, C, Shi, Y. Deposit date: 2018-09-07 Release date: 2019-03-13 Last modified: 2020-10-14 Method: ELECTRON MICROSCOPY (3 Å) Cite: Structures of the human spliceosomes before and after release of the ligated exon. Cell Res., 29, 2019
7W5B	The cryo-EM structure of human C* complex Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... Authors: Zhan, X, Lu, Y, Shi, Y. Deposit date: 2021-11-29 Release date: 2022-06-22 Last modified: 2022-08-17 Method: ELECTRON MICROSCOPY (4.3 Å) Cite: Mechanism of exon ligation by human spliceosome. Mol.Cell, 82, 2022
6ID0	Cryo-EM structure of a human intron lariat spliceosome prior to Prp43 loaded (ILS1 complex) at 2.9 angstrom resolution Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, CWF19-like protein 2, Cell division cycle 5-like protein, ... Authors: Zhang, X, Zhan, X, Yan, C, Shi, Y. Deposit date: 2018-09-07 Release date: 2019-03-13 Last modified: 2020-10-14 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Structures of the human spliceosomes before and after release of the ligated exon. Cell Res., 29, 2019
6ID1	Cryo-EM structure of a human intron lariat spliceosome after Prp43 loaded (ILS2 complex) at 2.9 angstrom resolution Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, CWF19-like protein 2, Cell division cycle 5-like protein, ... Authors: Zhang, X, Zhan, X, Yan, C, Shi, Y. Deposit date: 2018-09-07 Release date: 2019-03-13 Last modified: 2020-10-14 Method: ELECTRON MICROSCOPY (2.86 Å) Cite: Structures of the human spliceosomes before and after release of the ligated exon. Cell Res., 29, 2019
7S9P	Ternary complex of DNA Polymerase Beta with Template Fapy-dG and an incoming dCTP analog Descriptor: 2'-deoxy-5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*(FAP)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... Authors: Freudenthal, B.D, Ryan, B.J, Smith, M.R. Deposit date: 2021-09-21 Release date: 2022-08-03 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.86 Å) Cite: Structural Dynamics of a Common Mutagenic Oxidative DNA Lesion in Duplex DNA and during DNA Replication. J.Am.Chem.Soc., 144, 2022
7S9Q	Ternary complex of DNA Polymerase Beta with Template Fapy-dG and an incoming dATP analog Descriptor: 2'-deoxy-5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]adenosine, DNA (5'-D(*CP*CP*GP*AP*CP*(FAP)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ... Authors: Freudenthal, B.D, Ryan, B.J, Smith, M.R. Deposit date: 2021-09-21 Release date: 2022-08-03 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural Dynamics of a Common Mutagenic Oxidative DNA Lesion in Duplex DNA and during DNA Replication. J.Am.Chem.Soc., 144, 2022
4R5P	Crystal structure of HIV-1 reverse transcriptase (RT) with DNA and a nucleoside triphosphate mimic alpha-carboxy nucleoside phosphonate inhibitor Descriptor: 5'-D(*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*(MRG)P*CP*GP*CP*CP*G)-3', 5'-D(*TP*GP*GP*AP*CP*GP*GP*CP*GP*CP*CP*CP*GP*AP*AP*CP*AP*GP*GP*GP*AP*CP*TP*G)-3', HIV-1 reverse transcriptase, ... Authors: Das, K, Martinez, S.E, Arnold, E. Deposit date: 2014-08-21 Release date: 2015-03-11 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.894 Å) Cite: Alpha-carboxy nucleoside phosphonates as universal nucleoside triphosphate mimics. Proc.Natl.Acad.Sci.USA, 112, 2015
8Q7W	Structure of the recycling U5 snRNP bound to chaperone CD2BP2 (State 3) Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, CD2 antigen cytoplasmic tail-binding protein 2, GUANOSINE-5'-TRIPHOSPHATE, ... Authors: Riabov Bassat, D, Plaschka, C, Vorlaender, M.K. Deposit date: 2023-08-17 Release date: 2024-04-17 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Structural basis of human U5 snRNP late biogenesis and recycling. Nat.Struct.Mol.Biol., 31, 2024
8Q7X	Structure of the recycling U5 snRNP bound to chaperone CD2BP2 (State 4) Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, CD2 antigen cytoplasmic tail-binding protein 2, GUANOSINE-5'-TRIPHOSPHATE, ... Authors: Riabov Bassat, D, Plaschka, C, Vorlaender, M.K. Deposit date: 2023-08-17 Release date: 2024-04-17 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (4.6 Å) Cite: Structural basis of human U5 snRNP late biogenesis and recycling. Nat.Struct.Mol.Biol., 31, 2024
8Q7V	Structure of the recycling U5 snRNP bound to chaperones CD2BP2 and TSSC4 (State 1) Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, CD2 antigen cytoplasmic tail-binding protein 2, GUANOSINE-5'-TRIPHOSPHATE, ... Authors: Riabov Bassat, D, Plaschka, C, Vorlaender, M.K. Deposit date: 2023-08-17 Release date: 2024-04-17 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Structural basis of human U5 snRNP late biogenesis and recycling. Nat.Struct.Mol.Biol., 31, 2024
8Q7Q	Structure of the recycling U5 snRNP bound to chaperones CD2BP2 and TSSC4 (State 2) Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, CD2 antigen cytoplasmic tail-binding protein 2, GUANOSINE-5'-TRIPHOSPHATE, ... Authors: Riabov Bassat, D, Plaschka, C, Vorlaender, M.K. Deposit date: 2023-08-16 Release date: 2024-04-17 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Structural basis of human U5 snRNP late biogenesis and recycling. Nat.Struct.Mol.Biol., 31, 2024
5YVG	Crystal structure of Karyopherin beta2 in complex with FUS(full length) Descriptor: RNA-binding protein FUS, Transportin-1 Authors: Yoshizawa, T, Fung, H.Y.J, Chook, Y.M. Deposit date: 2017-11-25 Release date: 2018-05-16 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (4.05 Å) Cite: Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites. Cell, 173, 2018
7AQO	yeast THO-Sub2 complex dimer Descriptor: BJ4_G0025130.mRNA.1.CDS.1, EM14S01-3B_G0007820.mRNA.1.CDS.1, TEX1 isoform 1, ... Authors: Schuller, S.K, Schuller, J.M, Prabu, R.J, Baumgartner, M, Bonneau, F, basquin, J, Conti, E. Deposit date: 2020-10-22 Release date: 2020-12-02 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (4.5 Å) Cite: Structural insights into the nucleic acid remodeling mechanisms of the yeast THO-Sub2 complex. Elife, 9, 2020
3EVA	Crystal structure of yellow fever virus methyltransferase complexed with S-adenosyl-L-homocysteine Descriptor: RNA-directed RNA polymerase NS5, S-ADENOSYL-L-HOMOCYSTEINE Authors: Thompson, A.A, Geiss, B.J, Peersen, O.B. Deposit date: 2008-10-13 Release date: 2009-01-06 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Analysis of flavivirus NS5 methyltransferase cap binding. J.Mol.Biol., 385, 2009
3EVG	Crystal structure of Dengue-2 virus methyltransferase complexed with S-adenosyl-L-homocysteine Descriptor: RNA-directed RNA polymerase NS5, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION Authors: Thompson, A.A, Geiss, B.J, Peersen, O.B. Deposit date: 2008-10-13 Release date: 2009-01-06 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Analysis of flavivirus NS5 methyltransferase cap binding. J.Mol.Biol., 385, 2009
5SUQ	Crystal structure of the THO-Sub2 complex Descriptor: 12-TUNGSTOPHOSPHATE, ATP-dependent RNA helicase SUB2, Tex1, ... Authors: Ren, Y, Blobel, G. Deposit date: 2016-08-03 Release date: 2017-01-18 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (6 Å) Cite: Structural and biochemical analyses of the DEAD-box ATPase Sub2 in association with THO or Yra1. Elife, 6, 2017
3EVB	Crystal structure of yellow fever virus methyltransferase complexed with S-adenosyl-L-homocysteine Descriptor: RNA-directed RNA polymerase NS5, S-ADENOSYL-L-HOMOCYSTEINE Authors: Thompson, A.A, Geiss, B.J, Peersen, O.B. Deposit date: 2008-10-13 Release date: 2009-01-06 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Analysis of flavivirus NS5 methyltransferase cap binding. J.Mol.Biol., 385, 2009
2HUA	Solution Structure of CSFV IRES Domain IIa Descriptor: CSFV IRES Domain IIa Authors: Locker, N, Easton, L.E, Lukavsky, P.J. Deposit date: 2006-07-26 Release date: 2007-04-17 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: HCV and CSFV IRES domain II mediate eIF2 release during 80S ribosome assembly. Embo J., 26, 2007
7PRE	Solution structure of the NRDI domain of Nab3 Descriptor: HLJ1_G0022400.mRNA.1.CDS.1 Authors: Chaves-Arquero, B, Martinez-Lumbreras, S, Perez-Canadillas, J.M. Deposit date: 2021-09-21 Release date: 2022-01-12 Last modified: 2024-06-19 Method: SOLUTION NMR Cite: Structural basis of Nrd1-Nab3 heterodimerization. Life Sci Alliance, 5, 2022
7Z27	Crystal structure of the SPOC domain of human RBM15 Descriptor: RNA-binding protein 15 Authors: Grishkovskaya, I, Appel, L.M, Djinovic-Carugo, K, Slade, D. Deposit date: 2022-02-25 Release date: 2022-12-07 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.45 Å) Cite: The SPOC domain is a phosphoserine binding module that bridges transcription machinery with co- and post-transcriptional regulators. Nat Commun, 14, 2023
3PMN	ternary crystal structure of polymerase lambda variant with a GT mispair at the primer terminus with Mn2+ in the active site Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]guanosine, 5'-D(*CP*AP*GP*TP*AP*G)-3', 5'-D(*CP*GP*GP*CP*CP*TP*TP*AP*CP*TP*G)-3', ... Authors: Bebenek, K, Pedersen, L.C, Kunkel, T.A. Deposit date: 2010-11-17 Release date: 2011-02-02 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Replication infidelity via a mismatch with Watson-Crick geometry. Proc.Natl.Acad.Sci.USA, 108, 2011
1NBS	Crystal structure of the specificity domain of Ribonuclease P RNA Descriptor: LEAD (II) ION, MAGNESIUM ION, RIBONUCLEASE P RNA Authors: Krasilnikov, A.S, Yang, X, Pan, T, Mondragon, A. Deposit date: 2002-12-03 Release date: 2003-02-18 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (3.15 Å) Cite: Crystal structure of the specificity domain of Ribonuclease P Nature, 421, 2003

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