7S9Q
Ternary complex of DNA Polymerase Beta with Template Fapy-dG and an incoming dATP analog
Summary for 7S9Q
Entry DOI | 10.2210/pdb7s9q/pdb |
Descriptor | DNA polymerase beta, DNA (5'-D(P*GP*TP*CP*GP*G)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ... (9 entities in total) |
Functional Keywords | polymerase beta, fapy-dg, mutagenic, dna binding protein-dna complex, dna binding protein/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 48496.50 |
Authors | Freudenthal, B.D.,Ryan, B.J.,Smith, M.R. (deposition date: 2021-09-21, release date: 2022-08-03, Last modification date: 2023-10-18) |
Primary citation | Ryan, B.J.,Yang, H.,Bacurio, J.H.T.,Smith, M.R.,Basu, A.K.,Greenberg, M.M.,Freudenthal, B.D. Structural Dynamics of a Common Mutagenic Oxidative DNA Lesion in Duplex DNA and during DNA Replication. J.Am.Chem.Soc., 144:8054-8065, 2022 Cited by PubMed: 35499923DOI: 10.1021/jacs.2c00193 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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