PDB: 340 resultsInfo pagesStatus searchChemie searchBIRD

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3HZQ	Structure of a tetrameric MscL in an expanded intermediate state Descriptor: Large-conductance mechanosensitive channel Authors: Liu, Z.F, Gandhi, C.S, Rees, D.C. Deposit date: 2009-06-24 Release date: 2009-08-25 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (3.82 Å) Cite: Structure of a tetrameric MscL in an expanded intermediate state. Nature, 461, 2009
3EXJ	Crystal Structure of a p53 Core Tetramer Bound to DNA Descriptor: 5'-D(*DTP*DTP*DGP*DAP*DGP*DCP*DAP*DTP*DGP*DCP*DTP*DC)-3', 5'-D(P*DGP*DAP*DGP*DCP*DAP*DTP*DGP*DCP*DTP*DCP*DA)-3', CITRATE ANION, ... Authors: Malecka, K.A. Deposit date: 2008-10-16 Release date: 2008-12-16 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structure of a p53 core tetramer bound to DNA. Oncogene, 28, 2009
3KMD	Crystal structure of the p53 core domain bound to a full consensus site as a self-assembled tetramer Descriptor: 5'-D(*GP*GP*GP*CP*AP*TP*GP*CP*CP*TP*AP*GP*GP*CP*AP*TP*GP*CP*C)-3', Cellular tumor antigen p53, ZINC ION Authors: Chen, Y, Dey, R, Chen, L. Deposit date: 2009-11-10 Release date: 2010-02-23 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Crystal structure of the p53 core domain bound to a full consensus site as a self-assembled tetramer. Structure, 18, 2010
3KZ8	Diversity in DNA recognition by p53 revealed by crystal structures with Hoogsteen base pairs (p53-DNA complex 3) Descriptor: Cellular tumor antigen p53, DNA (5'-D(*TP*GP*GP*GP*CP*AP*TP*GP*CP*CP*CP*GP*GP*GP*CP*AP*TP*GP*CP*CP*C)-3'), IODIDE ION, ... Authors: Rozenberg, H, Suad, O, Shakked, Z. Deposit date: 2009-12-08 Release date: 2010-03-31 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.91 Å) Cite: Diversity in DNA recognition by p53 revealed by crystal structures with Hoogsteen base pairs Nat.Struct.Mol.Biol., 17, 2010
3GCT	STRUCTURE OF GAMMA-*CHYMOTRYPSIN IN THE RANGE $P*H 2.0 TO $P*H 10.5 SUGGESTS THAT GAMMA-CHYMOTRYPSIN IS A COVALENT ACYL-ENZYME ADDUCT AT LOW $P*H Descriptor: GAMMA-CHYMOTRYPSIN A, SULFATE ION, UNK PRO GLY ALA TYR PEPTIDE Authors: Dixon, M.M, Matthews, B.W. Deposit date: 1990-09-04 Release date: 1991-10-15 Last modified: 2024-06-05 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Structure of gamma-chymotrypsin in the range pH 2.0 to pH 10.5 suggests that gamma-chymotrypsin is a covalent acyl-enzyme adduct at low pH. Int.J.Biol.Macromol., 13, 1991
7DVD	The crystal structure of p53 DNA binding domain and PUMA complex Descriptor: Bcl-2-binding component 3, isoforms 1/2, Cellular tumor antigen p53, ... Authors: Han, C.W, Lee, H.N, Jeong, M.S, Jang, S.B. Deposit date: 2021-01-13 Release date: 2021-08-04 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.59 Å) Cite: Structural basis of the p53 DNA binding domain and PUMA complex. Biochem.Biophys.Res.Commun., 548, 2021
5BUA	Lysine 120-acetylated P53 DNA binding domain in a complex with DNA. Descriptor: Cellular tumor antigen p53, DNA (5'-D(P*GP*GP*AP*CP*AP*TP*GP*TP*CP*C)-3'), ZINC ION Authors: Arbely, E, Vainer, R. Deposit date: 2015-06-03 Release date: 2016-07-06 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.812 Å) Cite: Structural Basis for p53 Lys120-Acetylation-Dependent DNA-Binding Mode. J.Mol.Biol., 428, 2016
7EDS	Human p53 core domain with germline hot spot mutation M133T in complex with the natural PIG3 p53-response element and Arsenic Descriptor: ARSENIC, Cellular tumor antigen p53, PIG3 anti-sense strand, ... Authors: Xing, Y.F, Lu, M. Deposit date: 2021-03-17 Release date: 2022-06-22 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.77 Å) Cite: Arsenic-bound p53 Hotspot mutant M133T in complex with the natural PIG3 p53-response element To Be Published
7EEU	Human p53 core domain with hot spot mutation R282W in complex with the natural CDKN1A(p21) p53-response element and Arsenic Descriptor: ARSENIC, CDKN1A(p21) anti-sense strand, CDKN1A(p21) sense strand, ... Authors: Xing, Y.F, Lu, M. Deposit date: 2021-03-19 Release date: 2022-06-22 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Human p53 core domain with hot spot mutation R282W in complex with the natural CDKN1A(p21) p53-response element and Arsenic To Be Published
1KDQ	Crystal Structure Analysis of the Mutant S189D Rat Chymotrypsin Descriptor: CALCIUM ION, CHYMOTRYPSIN B, B CHAIN, ... Authors: Szabo, E, Bocskei, Z, Naray-Szabo, G, Graf, L, Venekei, I. Deposit date: 2001-11-13 Release date: 2003-06-10 Last modified: 2021-10-27 Method: X-RAY DIFFRACTION (2.55 Å) Cite: Three Dimensional Structures of S189D Chymotrypsin and D189S Trypsin Mutants: The Effect of Polarity at Site 189 on a Protease-specific Stabilization of the Substrate-binding Site J.Mol.Biol., 331, 2003
2CHA	THE STRUCTURE OF CRYSTALLINE ALPHA-CHYMOTRYPSIN, $V.THE ATOMIC STRUCTURE OF TOSYL-ALPHA-CHYMOTRYPSIN AT 2 ANGSTROMS RESOLUTION Descriptor: ALPHA-CHYMOTRYPSIN A, PARA-TOLUENE SULFONATE Authors: Birktoft, J.J, Blow, D.M. Deposit date: 1975-01-01 Release date: 1977-01-18 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2 Å) Cite: Structure of crystalline -chymotrypsin. V. The atomic structure of tosyl- -chymotrypsin at 2 A resolution. J.Mol.Biol., 68, 1972
1YPH	High resolution structure of bovine alpha-chymotrypsin Descriptor: CHYMOTRYPSIN A, chain A, chain B, ... Authors: Razeto, A, Galunsky, B, Kasche, V, Wilson, K.S, Lamzin, V.S. Deposit date: 2005-01-31 Release date: 2006-02-14 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.34 Å) Cite: High resolution structure of native bovine alpha-chymotrypsin To be Published
5CHA	THE REFINEMENT AND THE STRUCTURE OF THE DIMER OF ALPHA-*CHYMOTRYPSIN AT 1.67-*ANGSTROMS RESOLUTION Descriptor: ALPHA-CHYMOTRYPSIN A Authors: Blevins, R.A, Tulinsky, A. Deposit date: 1985-01-22 Release date: 1985-04-01 Last modified: 2024-06-05 Method: X-RAY DIFFRACTION (1.67 Å) Cite: The refinement and the structure of the dimer of alpha-chymotrypsin at 1.67-A resolution. J.Biol.Chem., 260, 1985
7GCH	STRUCTURE OF CHYMOTRYPSIN-*TRIFLUOROMETHYL KETONE INHIBITOR COMPLEXES. COMPARISON OF SLOWLY AND RAPIDLY EQUILIBRATING INHIBITORS Descriptor: 1,1,1-TRIFLUORO-3-((N-ACETYL)-L-LEUCYLAMIDO)-4-PHENYL-BUTAN-2-ONE(N-ACETYL-L-LEUCYL-L-PHENYLALANYL TRIFLUOROMETHYL KETONE), GAMMA-CHYMOTRYPSIN A Authors: Brady, K, Ringe, D, Abeles, R.H. Deposit date: 1990-04-06 Release date: 1990-10-15 Last modified: 2024-06-05 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structure of chymotrypsin-trifluoromethyl ketone inhibitor complexes: comparison of slowly and rapidly equilibrating inhibitors. Biochemistry, 29, 1990
2ECY	Solution structure of the Zinc finger, C3HC4 type (RING finger)" domain of TNF receptor-associated factor 3 Descriptor: TNF receptor-associated factor 3, ZINC ION Authors: Abe, H, Miyamoto, K, Tochio, N, Yoneyama, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2007-02-14 Release date: 2008-02-26 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Solution structure of the Zinc finger, C3HC4 type (RING finger)" domain of TNF receptor-associated factor 3 To be Published
1L5J	CRYSTAL STRUCTURE OF E. COLI ACONITASE B. Descriptor: ACONITATE ION, Aconitate hydratase 2, FE3-S4 CLUSTER Authors: Williams, C.H, Stillman, T.J, Barynin, V.V, Sedelnikova, S.E, Tang, Y, Green, J, Guest, J.R, Artymiuk, P.J. Deposit date: 2002-03-07 Release date: 2002-06-12 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.4 Å) Cite: E. coli aconitase B structure reveals a HEAT-like domain with implications for protein-protein recognition. Nat.Struct.Biol., 9, 2002
2AHI	Structural Basis of DNA Recognition by p53 Tetramers (complex III) Descriptor: 5'-D(*CP*GP*GP*AP*CP*AP*TP*GP*TP*CP*CP*G)-3', Cellular tumor antigen p53, ZINC ION Authors: Kitayner, M, Rozenberg, H, Kessler, N, Rabinovich, D, Shakked, Z. Deposit date: 2005-07-28 Release date: 2006-07-11 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Structural Basis of DNA Recognition by p53 Tetramers Mol.Cell, 22, 2006
1KZY	Crystal Structure of the 53bp1 BRCT Region Complexed to Tumor Suppressor P53 Descriptor: CELLULAR TUMOR ANTIGEN P53, TUMOR SUPPRESSOR P53-BINDING PROTEIN 1, ZINC ION Authors: Joo, W.S, Jeffrey, P.D, Cantor, S.B, Finnin, M.S, Livingston, D.M, Pavletich, N.P. Deposit date: 2002-02-08 Release date: 2002-03-20 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structure. Genes Dev., 16, 2002
1K2I	Crystal Structure of Gamma-Chymotrypsin in Complex with 7-Hydroxycoumarin Descriptor: 2,4-DIHYDROXY-TRANS CINNAMIC ACID, CHYMOTRYPSINOGEN A, SULFATE ION Authors: Ghani, U, Ng, K.K.S, Atta-ur-Rahman, Choudhary, M.I, Ullah, N, James, M.N.G. Deposit date: 2001-09-27 Release date: 2001-12-05 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal structure of gamma-chymotrypsin in complex with 7-hydroxycoumarin. J.Mol.Biol., 314, 2001
7EAX	Crystal complex of p53-V272M and antimony ion Descriptor: ANTIMONY (III) ION, Cellular tumor antigen p53, ZINC ION Authors: Lu, M, Tang, Y. Deposit date: 2021-03-08 Release date: 2022-02-16 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.55 Å) Cite: Repurposing antiparasitic antimonials to noncovalently rescue temperature-sensitive p53 mutations. Cell Rep, 39, 2022
2ADY	Structural Basis of DNA Recognition by p53 Tetramers (complex IV) Descriptor: 5'-D(*CP*GP*GP*AP*CP*AP*TP*GP*TP*CP*CP*G)-3', Cellular tumor antigen p53, ZINC ION Authors: Kitayner, M, Rozenberg, H, Kessler, N, Rabinovich, D, Shakked, Z. Deposit date: 2005-07-21 Release date: 2006-07-11 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structural Basis of DNA Recognition by p53 Tetramers Mol.Cell, 22, 2006
2AC0	Structural Basis of DNA Recognition by p53 Tetramers (complex I) Descriptor: 5'-D(*CP*GP*GP*GP*CP*AP*TP*GP*CP*CP*CP*G)-3', Cellular tumor antigen p53, ZINC ION Authors: Kitayner, M, Rozenberg, H, Kessler, N, Rabinovich, D, Shakked, Z. Deposit date: 2005-07-18 Release date: 2006-07-11 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structural Basis of DNA Recognition by p53 Tetramers Mol.Cell, 22, 2006
2CGA	BOVINE CHYMOTRYPSINOGEN A. X-RAY CRYSTAL STRUCTURE ANALYSIS AND REFINEMENT OF A NEW CRYSTAL FORM AT 1.8 ANGSTROMS RESOLUTION Descriptor: CHYMOTRYPSINOGEN A Authors: Wang, D, Bode, W, Huber, R. Deposit date: 1987-01-16 Release date: 1987-04-16 Last modified: 2024-06-05 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Bovine chymotrypsinogen A X-ray crystal structure analysis and refinement of a new crystal form at 1.8 A resolution. J.Mol.Biol., 185, 1985
5ECG	Crystal structure of the BRCT domains of 53BP1 in complex with p53 and H2AX-pSer139 (gammaH2AX) Descriptor: Cellular tumor antigen p53, SEP-GLN-GLU-TYR, Tumor suppressor p53-binding protein 1, ... Authors: Day, M, Oliver, A.W, Pearl, L.H. Deposit date: 2015-10-20 Release date: 2015-12-16 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3 Å) Cite: ATM Localization and Heterochromatin Repair Depend on Direct Interaction of the 53BP1-BRCT2 Domain with gamma H2AX. Cell Rep, 13, 2015
2FEJ	Solution structure of human p53 DNA binding domain. Descriptor: Cellular tumor antigen p53, ZINC ION Authors: Perez-Canadillas, J.M, Tidow, H, Freund, S.M, Rutherford, T.J, Ang, H.C, Fersht, A.R. Deposit date: 2005-12-16 Release date: 2006-01-31 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Solution structure of p53 core domain: Structural basis for its instability Proc.Natl.Acad.Sci.Usa, 103, 2006

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