3EXJ
Crystal Structure of a p53 Core Tetramer Bound to DNA
Summary for 3EXJ
| Entry DOI | 10.2210/pdb3exj/pdb |
| Related | 3EXL |
| Descriptor | mouse p53 core domain, 5'-D(P*DGP*DAP*DGP*DCP*DAP*DTP*DGP*DCP*DTP*DCP*DA)-3', 5'-D(*DTP*DTP*DGP*DAP*DGP*DCP*DAP*DTP*DGP*DCP*DTP*DC)-3', ... (6 entities in total) |
| Functional Keywords | protein-dna complex, acetylation, activator, anti-oncogene, apoptosis, cell cycle, covalent protein-rna linkage, cytoplasm, disease mutation, dna-binding, endoplasmic reticulum, metal-binding, methylation, nucleus, phosphoprotein, transcription, transcription regulation, ubl conjugation, zinc, transcription-dna complex, transcription/dna |
| Biological source | Mus musculus (mouse) |
| Cellular location | Cytoplasm : P02340 |
| Total number of polymer chains | 4 |
| Total formula weight | 52098.64 |
| Authors | Malecka, K.A. (deposition date: 2008-10-16, release date: 2008-12-16, Last modification date: 2023-12-27) |
| Primary citation | Malecka, K.A.,Ho, W.C.,Marmorstein, R. Crystal structure of a p53 core tetramer bound to DNA. Oncogene, 28:325-333, 2009 Cited by PubMed: 18978813DOI: 10.1038/onc.2008.400 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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