PDB: 59042 resultsInfo pagesStatus searchChemie searchBIRD

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4HV4	2.25 Angstrom resolution crystal structure of UDP-N-acetylmuramate--L-alanine ligase (murC) from Yersinia pestis CO92 in complex with AMP Descriptor: ADENOSINE MONOPHOSPHATE, BETA-MERCAPTOETHANOL, UDP-N-acetylmuramate--L-alanine ligase Authors: Halavaty, A.S, Minasov, G, Dubrovska, I, Winsor, J, Shuvalova, L, Peterson, S, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) Deposit date: 2012-11-05 Release date: 2012-11-21 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.25 Å) Cite: 2.25 Angstrom resolution crystal structure of UDP-N-acetylmuramate--L-alanine ligase (murC) from Yersinia pestis CO92 in complex with AMP To be Published
8IZJ	Crystal structure of Escherichia coli Adenine Phosphoribosyltransferase (APRT) in complex with AMP Descriptor: ADENOSINE MONOPHOSPHATE, Adenine phosphoribosyltransferase, CHLORIDE ION, ... Authors: Yadav, P, Kushwaha, G.S, Bhavesh, N.S. Deposit date: 2023-04-07 Release date: 2024-04-10 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Crystal structure of Escherichia coli Adenine Phosphoribosyltransferase (APRT) in complex with AMP To Be Published
3OCP	Crystal structure of cAMP bound cGMP-dependent protein kinase(92-227) Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, PRKG1 protein Authors: Kim, J.J, Huang, G, Kwon, T.K, Zwart, P, Headd, J, Kim, C. Deposit date: 2010-08-10 Release date: 2011-05-11 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.49 Å) Cite: Co-Crystal Structures of PKG Ibeta (92-227) with cGMP and cAMP Reveal the Molecular Details of Cyclic-Nucleotide Binding Plos One, 6, 2011
8V4O	Crystal structure of Acetyl-CoA synthetase 2 in complex with AMP from Candida albicans Descriptor: ADENOSINE MONOPHOSPHATE, Acetyl-coenzyme A synthetase 2, CHLORIDE ION, ... Authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2023-11-29 Release date: 2023-12-06 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Crystal structure of Acetyl-CoA synthetase 2 in complex with AMP from Candida albicans To be published
7L8N	Diadenylate cyclase with AMP from Streptococcus mutans Descriptor: ACETATE ION, ADENOSINE MONOPHOSPHATE, CHLORIDE ION, ... Authors: Hua, Z, Hui, W. Deposit date: 2020-12-31 Release date: 2022-01-19 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.94 Å) Cite: Diadenylate cyclase with AMP from Streptococcus mutans To Be Published
8EFM	Structure of coral STING receptor from Stylophora pistillata in complex with 2',3'-cGAMP Descriptor: SULFATE ION, Stimulator of interferon genes protein, cGAMP Authors: Li, Y, Slavik, K.M, Morehouse, B.R, Mears, K, Kranzusch, P.J. Deposit date: 2022-09-08 Release date: 2023-07-05 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (2.13 Å) Cite: cGLRs are a diverse family of pattern recognition receptors in innate immunity. Cell, 186, 2023
9C3G	human cGAS core domain (K427E/K428E) bound to Cladophorol A Descriptor: Cyclic GMP-AMP synthase, ZINC ION, cladophorol A Authors: Kissai, M, Stanfield, R.L, Lairson, L.L. Deposit date: 2024-05-31 Release date: 2025-03-05 Method: X-RAY DIFFRACTION (2.75 Å) Cite: Cladophorol-A is an inhibitor of cyclic GMP-AMP synthase. Bioorg.Med.Chem.Lett., 115, 2025
7T29	Crystal Structure of Adenylosuccinate lyase (ASL) from Pseudomonas aeruginosa complexed with AMP Descriptor: 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, Adenylosuccinate lyase Authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2021-12-03 Release date: 2021-12-15 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Crystal Structure of Adenylosuccinate lyase (ASL) from Pseudomonas aeruginosa complexed with AMP to be published
7KWM	CtBP1 (28-375) L182F/V185T - AMP Descriptor: ADENOSINE MONOPHOSPHATE, C-terminal-binding protein 1, CALCIUM ION Authors: Royer, W.E, Del Campo, M. Deposit date: 2020-12-01 Release date: 2021-02-03 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.3 Å) Cite: NAD(H) phosphates mediate tetramer assembly of human C-terminal binding protein (CtBP). J.Biol.Chem., 296, 2021
8U7K	WT sea urchin SLC9C1 with 5mM cAMP at pH 6 in Na+ - Grip (G) conformation Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Digitonin, ... Authors: Chowdhury, S, Pal, K. Deposit date: 2023-09-15 Release date: 2025-03-26 Method: ELECTRON MICROSCOPY (4.1 Å) Cite: Structure of WT sp9C1 with 5mM cAMP at pH 6 in Na+ - Grip (G) conformation To Be Published
8U7O	WT sea urchin SLC9C1 with 5mM cAMP at pH 6 in Na+ - Grip and Twist (GnT) conformation Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Digitonin, ... Authors: Chowdhury, S, Pal, K. Deposit date: 2023-09-15 Release date: 2025-03-26 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Structure of WT sp9C1 with 5mM cAMP at pH 6 in Na+ - Grip and Twist (GnT) conformation To Be Published
8U7P	WT sea urchin SLC9C1 with 5mM cAMP at pH 6 in Na+ - Grip and Twist Like (GnTL) conformation Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Digitonin, ... Authors: Chowdhury, S, Pal, K. Deposit date: 2023-09-15 Release date: 2025-03-26 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: Structure of WT sp9C1 with 5mM cAMP at pH 6 in Na+ - Grip and Twist Like (GnTL) conformation To Be Published
9DQM	Crystal Structure Pyrophosphate-fructose 6-phosphate 1-phosphotransferase 1 (Pfk1) from Trichomonas vaginalis (AMP bound) Descriptor: ADENOSINE MONOPHOSPHATE, PHOSPHATE ION, Pyrophosphate--fructose 6-phosphate 1-phosphotransferase 1 Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2024-09-24 Release date: 2024-10-02 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal Structure Pyrophosphate-fructose 6-phosphate 1-phosphotransferase 1 (Pfk1) from Trichomonas vaginalis (AMP bound) To be published
8GIN	Structure of Ternary Complex of mouse cGAS with dsDNA and Bound ATP: with 10mM Mg2+ and 0.015mM Mn2+ Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MAGNESIUM ION, ... Authors: Wu, S, Sohn, J. Deposit date: 2023-03-14 Release date: 2024-05-22 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.75 Å) Cite: The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
8VW0	Crystal Structure of Apo UDP-N-acetylmuramoylalanine--D-glutamate ligase (MurD) from E. coli (AMP bound) Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE MONOPHOSPHATE, CALCIUM ION, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2024-01-31 Release date: 2024-02-14 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Crystal Structure of Apo UDP-N-acetylmuramoylalanine--D-glutamate ligase (MurD) from E. coli (AMP bound) To be published
8G1J	Structure of Ternary Complex of cGAS with dsDNA and Bound ATP and ITP Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, GUANOSINE-5'-TRIPHOSPHATE, ... Authors: Wu, S, Sohn, J. Deposit date: 2023-02-02 Release date: 2024-05-22 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.3 Å) Cite: The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
8G23	Structure of Ternary Complex of cGAS with dsDNA and Bound pppIpA Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MAGNESIUM ION, ... Authors: Wu, S, Sohn, J. Deposit date: 2023-02-03 Release date: 2024-05-22 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.71 Å) Cite: The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
8GIM	Structure of Ternary Complex of mouse cGAS with dsDNA and Bound ATP: with 10mM Mg2+ Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MAGNESIUM ION, ... Authors: Wu, S, Sohn, J. Deposit date: 2023-03-14 Release date: 2024-05-22 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.63 Å) Cite: The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
8GIP	Structure of Ternary Complex of mouse cGAS with dsDNA and Bound ATP: with 10mM Mg2+ and 0.040mM Mn2+ Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MAGNESIUM ION, ... Authors: Wu, S, Sohn, J. Deposit date: 2023-03-14 Release date: 2024-05-22 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.7 Å) Cite: The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
9D8S	Crystal Structure of calcium-dependent protein kinase 1 (CDPK1) from Cryptosporidium parvum (AMP/Mg bound) Descriptor: ADENOSINE MONOPHOSPHATE, CALCIUM ION, CHLORIDE ION, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2024-08-20 Release date: 2024-09-04 Method: X-RAY DIFFRACTION (2.12 Å) Cite: Crystal Structure of calcium-dependent protein kinase 1 (CDPK1) from Cryptosporidium parvum (AMP/Mg bound) To be published
8UZN	Crystal Structure of Betaine aldehyde dehydrogenase (BetB) from Klebsiella aerogenes (AMP bound) Descriptor: ADENOSINE MONOPHOSPHATE, Betaine aldehyde dehydrogenase, SODIUM ION Authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2023-11-15 Release date: 2023-12-06 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Crystal Structure of Betaine aldehyde dehydrogenase (BetB) from Klebsiella aerogenes (AMP bound) To be published
7U56	Crystal Structure of D-alanine--D-alanine ligase from Klebsiella pneumoniae subsp. pneumoniae in complex with AMP Descriptor: 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, CHLORIDE ION, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2022-03-01 Release date: 2022-03-09 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Crystal Structure of D-alanine--D-alanine ligase from Klebsiella pneumoniae subsp. pneumoniae in complex with AMP to be published
6HQ3	Structure of EAL Enzyme Bd1971 - halfsite-occupied form Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, EAL Enzyme Bd1971 Authors: Lovering, A.L, Cadby, I.T. Deposit date: 2018-09-24 Release date: 2019-07-31 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (2.79 Å) Cite: Nucleotide signaling pathway convergence in a cAMP-sensing bacterial c-di-GMP phosphodiesterase. Embo J., 38, 2019
6QZS	14-3-3 sigma in complex with FOXO1 pS256 peptide Descriptor: 14-3-3 protein sigma, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FOXO1 pS256 site, ... Authors: Ottmann, C, Wolter, M, Lau, R.A. Deposit date: 2019-03-12 Release date: 2019-07-31 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (1.9 Å) Cite: AMPK and AKT protein kinases hierarchically phosphorylate the N-terminus of the FOXO1 transcription factor, modulating interactions with 14-3-3 proteins. J.Biol.Chem., 294, 2019
8EAE	Structure of Ternary Complex of cGAS with dsDNA and Bound 5-pppG(2,5)pI Descriptor: Cyclic GMP-AMP synthase, MAGNESIUM ION, Palindromic DNA18, ... Authors: Wu, S, Sohn, J. Deposit date: 2022-08-29 Release date: 2023-10-25 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.56 Å) Cite: The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024

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