8G23
Structure of Ternary Complex of cGAS with dsDNA and Bound pppIpA
Summary for 8G23
Entry DOI | 10.2210/pdb8g23/pdb |
Descriptor | Cyclic GMP-AMP synthase, Palindromic DNA18, ADENOSINE-5'-TRIPHOSPHATE, ... (7 entities in total) |
Functional Keywords | transferase-dna complex, cgas, intermediate, immune system, immune system-dna complex, immune system/dna |
Biological source | Mus musculus (house mouse) More |
Total number of polymer chains | 6 |
Total formula weight | 108862.90 |
Authors | |
Primary citation | Wu, S.,Gabelli, S.B.,Sohn, J. The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15:4012-4012, 2024 Cited by PubMed: 38740774DOI: 10.1038/s41467-024-48365-3 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.71 Å) |
Structure validation
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