6QZS
14-3-3 sigma in complex with FOXO1 pS256 peptide
Summary for 6QZS
Entry DOI | 10.2210/pdb6qzs/pdb |
Related | 6qzr |
Descriptor | 14-3-3 protein sigma, FOXO1 pS256 site, GLYCEROL, ... (5 entities in total) |
Functional Keywords | protein binding, complex, foxo1, 14-3-3, peptide binding protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 59898.67 |
Authors | Ottmann, C.,Wolter, M.,Lau, R.A. (deposition date: 2019-03-12, release date: 2019-07-31, Last modification date: 2024-01-24) |
Primary citation | Saline, M.,Badertscher, L.,Wolter, M.,Lau, R.,Gunnarsson, A.,Jacso, T.,Norris, T.,Ottmann, C.,Snijder, A. AMPK and AKT protein kinases hierarchically phosphorylate the N-terminus of the FOXO1 transcription factor, modulating interactions with 14-3-3 proteins. J.Biol.Chem., 294:13106-13116, 2019 Cited by PubMed: 31308176DOI: 10.1074/jbc.RA119.008649 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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