6QZS
14-3-3 sigma in complex with FOXO1 pS256 peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, B) | 14-3-3 protein sigma | polymer | 253 | 28226.5 | 2 | UniProt (P31947) Pfam (PF00244) | Homo sapiens (Human) | Epithelial cell marker protein 1,Stratifin |
| 2 | B, D (P, C) | FOXO1 pS256 site | polymer | 12 | 1489.6 | 2 | UniProt (by SIFTS) (Q12778) | Homo sapiens | |
| 3 | E, G (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 4 | F (A) | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 282.3 | 1 | Chemie (B3P) | |||
| 5 | H, I, J, K (A, P, B, C) | water | water | 18.0 | 591 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 248 (UniProt: P31947)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Met -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 59432.1 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 466.5 | |
| All* | Total formula weight | 59898.7 |
