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6AZ6
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BU of 6az6 by Molmil
Streptococcus agalactiae GntR
Descriptor: GntR family transcriptional regulator
Authors:Pellock, S.J, Redinbo, M.R.
Deposit date:2017-09-10
Release date:2017-12-20
Last modified:2019-12-04
Method:X-RAY DIFFRACTION (1.909 Å)
Cite:Structural basis for the regulation of beta-glucuronidase expression by human gut Enterobacteriaceae.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5FMN
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BU of 5fmn by Molmil
The nickel-responsive transcriptional regulator InrS
Descriptor: INRS
Authors:Foster, A.W, Patterson, C.J, Robinson, N.J, Pohl, E.
Deposit date:2015-11-06
Release date:2017-02-01
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A tight tunable range for Ni(II) sensing and buffering in cells.
Nat. Chem. Biol., 13, 2017
7QAA
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BU of 7qaa by Molmil
Crystal structure of RARalpha/RXRalpha ligand binding domain heterodimer in complex with BMS614 and oleic acid
Descriptor: 4-[(4,4-DIMETHYL-1,2,3,4-TETRAHYDRO-[1,2']BINAPTHALENYL-7-CARBONYL)-AMINO]-BENZOIC ACID, Isoform Alpha-1-deltaBC of Retinoic acid receptor alpha, OLEIC ACID, ...
Authors:le Maire, A, Vivat, V, Guee, L, Blanc, P, Malosse, C, Chamot-Rooke, J, Germain, P, Bourguet, w.
Deposit date:2021-11-16
Release date:2022-10-05
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:Design and in vitro characterization of RXR variants as tools to investigate the biological role of endogenous rexinoids.
J.Mol.Endocrinol., 69, 2022
6FCM
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BU of 6fcm by Molmil
Crystal structure of human PCNA
Descriptor: Proliferating cell nuclear antigen
Authors:Housset, D, Frachet, P.
Deposit date:2017-12-20
Release date:2019-01-30
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Cytosolic PCNA interacts with p47phox and controls NADPH oxidase NOX2 activation in neutrophils.
J.Exp.Med., 216, 2019
6FCN
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BU of 6fcn by Molmil
Crystal structure of human PCNA soaked with p47phox(106-127) peptide
Descriptor: Proliferating cell nuclear antigen
Authors:Housset, D, Frachet, P.
Deposit date:2017-12-20
Release date:2019-01-30
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.22 Å)
Cite:Cytosolic PCNA interacts with p47phox and controls NADPH oxidase NOX2 activation in neutrophils.
J.Exp.Med., 216, 2019
5YSZ
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BU of 5ysz by Molmil
transcriptional regulator CelR-cellobiose complex
Descriptor: GLYCEROL, Transcriptional regulator, LacI family, ...
Authors:Fu, Y, Yeom, S.Y, Lee, D.H, Lee, S.G.
Deposit date:2017-11-16
Release date:2018-08-22
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.631 Å)
Cite:Structural and functional analyses of the cellulase transcription regulator CelR
FEBS Lett., 592, 2018
6PAI
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BU of 6pai by Molmil
Structure of the human DDB1-DDA1-DCAF15 E3 ubiquitin ligase bound to RBM39 and sulfonamide E7820
Descriptor: 3-cyano-N-(3-cyano-4-methyl-1H-indol-7-yl)benzene-1-sulfonamide, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DDB1- and CUL4-associated factor 15, ...
Authors:Volkov, O.A, Du, X.
Deposit date:2019-06-11
Release date:2019-09-18
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural Basis and Kinetic Pathway of RBM39 Recruitment to DCAF15 by a Sulfonamide Molecular Glue E7820.
Structure, 27, 2019
3WHB
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BU of 3whb by Molmil
Crystal structure of FadR from Bacillus subtilis, a transcriptional regulator involved in the regulation of fatty acid degradation
Descriptor: DODECYL-COA, Fatty acid metabolism regulator protein
Authors:Fujihashi, M, Nakatani, T, Miki, K.
Deposit date:2013-08-23
Release date:2014-03-19
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural characterization of a ligand-bound form of Bacillus subtilis FadR involved in the regulation of fatty acid degradation.
Proteins, 82, 2014
3WHC
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BU of 3whc by Molmil
Crystal structure of a transcriptional regulator FadR from Bacillus subtilis in complex with stearoyl-CoA
Descriptor: Fatty acid metabolism regulator protein, STEAROYL-COENZYME A
Authors:Fujihashi, M, Nakatani, T, Miki, K.
Deposit date:2013-08-23
Release date:2014-03-19
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural characterization of a ligand-bound form of Bacillus subtilis FadR involved in the regulation of fatty acid degradation.
Proteins, 82, 2014
8OIZ
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BU of 8oiz by Molmil
Crystal structure of human CRBN-DDB1 in complex with Pomalidomide
Descriptor: 1,2-ETHANEDIOL, DNA damage-binding protein 1, Protein cereblon, ...
Authors:Le Bihan, Y.-V, Cabry, M.P, van Montfort, R.L.M.
Deposit date:2023-03-23
Release date:2023-07-19
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A Degron Blocking Strategy Towards Improved CRL4 CRBN Recruiting PROTAC Selectivity.
Chembiochem, 24, 2023
8OJH
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BU of 8ojh by Molmil
Crystal structure of human CRBN-DDB1 in complex with compound 4
Descriptor: 1,2-ETHANEDIOL, 4-azanyl-2-[(3~{S})-2,6-bis(oxidanylidene)piperidin-3-yl]-7-methoxy-isoindole-1,3-dione, DNA damage-binding protein 1, ...
Authors:Cabry, M.P, Le Bihan, Y.-V, van Montfort, R.L.M.
Deposit date:2023-03-24
Release date:2023-07-19
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:A Degron Blocking Strategy Towards Improved CRL4 CRBN Recruiting PROTAC Selectivity.
Chembiochem, 24, 2023
7RMW
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BU of 7rmw by Molmil
Crystal structure of B. subtilis PurR bound to ppGpp
Descriptor: GUANOSINE-5',3'-TETRAPHOSPHATE, Pur operon repressor
Authors:Schumacher, M.A.
Deposit date:2021-07-28
Release date:2021-12-22
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:The nucleotide messenger (p)ppGpp is an anti-inducer of the purine synthesis transcription regulator PurR in Bacillus.
Nucleic Acids Res., 50, 2022
4E1R
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BU of 4e1r by Molmil
Crystal structure of the dimerization domain of Lsr2 from Mycobacterium tuberculosis in the P 31 2 1 space group
Descriptor: Protein lsr2
Authors:Summers, E.L, Meindl, K, Uson, I, Arcus, V.L.
Deposit date:2012-03-06
Release date:2012-06-20
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.041 Å)
Cite:The structure of the oligomerization domain of Lsr2 from Mycobacterium tuberculosis reveals a mechanism for chromosome organization and protection.
Plos One, 7, 2012
8RGH
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BU of 8rgh by Molmil
Structure of dynein-2 intermediate chain DYNC2I1 (WDR60) in complex with the dynein-2 heavy chain DYNC2H1.
Descriptor: Cytoplasmic dynein 2 intermediate chain 1, Cytoplasmic dynein 2 intermediate chain 2, Cytoplasmic dynein 2 light intermediate chain 1, ...
Authors:Mukhopadhyay, A.G, Toropova, K, Daly, L, Wells, J, Vuolo, L, Seda, M, Jenkins, D, Stephens, D.J, Roberts, A.J.
Deposit date:2023-12-13
Release date:2024-03-20
Last modified:2024-04-10
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structure and tethering mechanism of dynein-2 intermediate chains in intraflagellar transport.
Embo J., 43, 2024
7TB6
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BU of 7tb6 by Molmil
Structure of S. maltophilia CapW
Descriptor: S. maltophilia CapW, SULFATE ION
Authors:Blankenchip, C.L, Nguyen, J.V, Lau, R.K, Ye, Q, Corbett, K.D.
Deposit date:2021-12-21
Release date:2022-01-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Control of bacterial immune signaling by a WYL domain transcription factor.
Nucleic Acids Res., 50, 2022
6G1B
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BU of 6g1b by Molmil
Corynebacterium glutamicum OxyR, oxidized form
Descriptor: 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, FORMIC ACID, HYDROGEN PEROXIDE, ...
Authors:Young, D.R, Pedre, B.P, Messens, J.M.
Deposit date:2018-03-21
Release date:2018-12-05
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Structural snapshots of OxyR reveal the peroxidatic mechanism of H2O2sensing.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6G4R
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BU of 6g4r by Molmil
Corynebacterium glutamicum OxyR C206S mutant, H2O2-bound
Descriptor: 1,2-ETHANEDIOL, HYDROGEN PEROXIDE, Hydrogen peroxide-inducible genes activator, ...
Authors:Young, D.R, Pedre, B.P, Messens, J.M.
Deposit date:2018-03-28
Release date:2018-12-05
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Structural snapshots of OxyR reveal the peroxidatic mechanism of H2O2sensing.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6G1D
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BU of 6g1d by Molmil
Corynebacterium glutamicum OxyR C206 mutant
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, FORMIC ACID, ...
Authors:Young, D.R, Pedre, B.P, Messens, J.M.
Deposit date:2018-03-21
Release date:2018-12-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.992 Å)
Cite:Structural snapshots of OxyR reveal the peroxidatic mechanism of H2O2sensing.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
1D0E
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BU of 1d0e by Molmil
CRYSTAL STRUCTURES OF THE N-TERMINAL FRAGMENT FROM MOLONEY MURINE LEUKEMIA VIRUS REVERSE TRANSCRIPTASE COMPLEXED WITH NUCLEIC ACID: FUNCTIONAL IMPLICATIONS FOR TEMPLATE-PRIMER BINDING TO THE FINGERS DOMAIN
Descriptor: 5'-D(*TP*TP*TP*CP*AP*TP*GP*CP*AP*TP*G)-3', REVERSE TRANSCRIPTASE
Authors:Najmudin, S, Cote, M.L, Sun, D, Yohannan, S, Montano, S.P, Gu, J, Georgiadis, M.M.
Deposit date:1999-09-09
Release date:2000-04-04
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structures of an N-terminal fragment from Moloney murine leukemia virus reverse transcriptase complexed with nucleic acid: functional implications for template-primer binding to the fingers domain
J.Mol.Biol., 296, 2000
1MKM
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BU of 1mkm by Molmil
CRYSTAL STRUCTURE OF THE THERMOTOGA MARITIMA ICLR
Descriptor: FORMIC ACID, IclR transcriptional regulator, ZINC ION
Authors:Kim, Y, Zhang, R.G, Joachimiak, A, Skarina, T, Edwards, A, Savchenko, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2002-08-29
Release date:2002-09-11
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of Thermotoga maritima 0065, a member of the IclR transcriptional factor family.
J.Biol.Chem., 277, 2002
4E1P
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BU of 4e1p by Molmil
Crystal structure of the dimerization domain of Lsr2 from Mycobacterium tuberculosis in the P 1 21 1 space group
Descriptor: Protein lsr2
Authors:Summers, E.L, Meindl, K, Uson, I, Arcus, V.L.
Deposit date:2012-03-06
Release date:2012-06-20
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.728 Å)
Cite:The structure of the oligomerization domain of Lsr2 from Mycobacterium tuberculosis reveals a mechanism for chromosome organization and protection.
Plos One, 7, 2012
4JOL
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BU of 4jol by Molmil
Complex structure of AML1-ETO NHR2 domain with HEB fragment
Descriptor: Protein CBFA2T1, Transcription factor 12
Authors:Wang, Z, Patel, D.J.
Deposit date:2013-03-18
Release date:2013-06-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.906 Å)
Cite:A stable transcription factor complex nucleated by oligomeric AML1-ETO controls leukaemogenesis.
Nature, 500, 2013
2GM5
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BU of 2gm5 by Molmil
An activated, truncated gamma-delta resolvase tetramer
Descriptor: Transposon gamma-delta resolvase
Authors:Kamtekar, S, Ho, R.S, Li, W, Steitz, T.A.
Deposit date:2006-04-05
Release date:2006-06-27
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Implications of structures of synaptic tetramers of gamma delta resolvase for the mechanism of recombination.
Proc.Natl.Acad.Sci.Usa, 103, 2006
3PQK
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BU of 3pqk by Molmil
Crystal Structure of the transcriptional repressor BigR from Xylella fastidiosa
Descriptor: Biofilm growth-associated repressor
Authors:Benedetti, C.E, Guimaraes, B.G.
Deposit date:2010-11-26
Release date:2011-06-01
Last modified:2011-08-03
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Plant Pathogenic Bacteria Utilize Biofilm Growth-associated Repressor (BigR), a Novel Winged-helix Redox Switch, to Control Hydrogen Sulfide Detoxification under Hypoxia.
J.Biol.Chem., 286, 2011
6MAF
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BU of 6maf by Molmil
native BbvCI A2B2 tetramer at low resolution
Descriptor: BbvCI endonuclease subunit 1, BbvCI endonuclease subunit 2
Authors:Shen, B.W, Stoddard, B.L.
Deposit date:2018-08-27
Release date:2018-11-14
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.79 Å)
Cite:Structure, subunit organization and behavior of the asymmetric Type IIT restriction endonuclease BbvCI.
Nucleic Acids Res., 47, 2019

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