8RGH

Structure of dynein-2 intermediate chain DYNC2I1 (WDR60) in complex with the dynein-2 heavy chain DYNC2H1.

Summary for 8RGH

Entry DOI	10.2210/pdb8rgh/pdb
EMDB information	19133
Descriptor	Methylated-DNA--protein-cysteine methyltransferase,Cytoplasmic dynein 2 heavy chain 1, Cytoplasmic dynein 2 intermediate chain 1, Cytoplasmic dynein 2 intermediate chain 2, ... (5 entities in total)
Functional Keywords	dynein, cilia, intraflagellar transport, complex, transport protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	6
Total formula weight	760278.09
Authors	Mukhopadhyay, A.G.,Toropova, K.,Daly, L.,Wells, J.,Vuolo, L.,Seda, M.,Jenkins, D.,Stephens, D.J.,Roberts, A.J. (deposition date: 2023-12-13, release date: 2024-03-20, Last modification date: 2024-04-10)
Primary citation	Mukhopadhyay, A.G.,Toropova, K.,Daly, L.,Wells, J.N.,Vuolo, L.,Mladenov, M.,Seda, M.,Jenkins, D.,Stephens, D.J.,Roberts, A.J. Structure and tethering mechanism of dynein-2 intermediate chains in intraflagellar transport. Embo J., 43:1257-1272, 2024 Cited by PubMed: 38454149 DOI: 10.1038/s44318-024-00060-1 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.9 Å)

Structure validation