2X4M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2x4m by Molmil](/molmil-images/mine/2x4m) | Yersinia Pestis Plasminogen Activator Pla | Descriptor: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, COAGULASE/FIBRINOLYSIN, SULFATE ION | Authors: | Eren, E, Murphy, M, Goguen, J, van den Berg, B. | Deposit date: | 2010-02-05 | Release date: | 2010-07-28 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | An Active Site Water Network in the Plasminogen Activator Pla from Yersinia Pestis Structure, 18, 2010
|
|
8OEW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8oew by Molmil](/molmil-images/mine/8oew) | Structure of the mammalian Pol II-Elongin complex, lacking the ELOA latch (composite structure, structure 2) | Descriptor: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1, ... | Authors: | Chen, Y, Kokic, G, Dienemann, C, Dybkov, O, Urlaub, H, Cramer, P. | Deposit date: | 2023-03-13 | Release date: | 2023-10-18 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structure of the transcribing RNA polymerase II-Elongin complex. Nat.Struct.Mol.Biol., 30, 2023
|
|
8OEV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8oev by Molmil](/molmil-images/mine/8oev) | Structure of the mammalian Pol II-SPT6-Elongin complex, lacking ELOA latch (composite structure, structure 3) | Descriptor: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1, ... | Authors: | Chen, Y, Kokic, G, Dienemann, C, Dybkov, O, Urlaub, H, Cramer, P. | Deposit date: | 2023-03-13 | Release date: | 2023-10-18 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (2.86 Å) | Cite: | Structure of the transcribing RNA polymerase II-Elongin complex. Nat.Struct.Mol.Biol., 30, 2023
|
|
2QWC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qwc by Molmil](/molmil-images/mine/2qwc) | |
2XA0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2xa0 by Molmil](/molmil-images/mine/2xa0) | Crystal structure of BCL-2 in complex with a BAX BH3 peptide | Descriptor: | APOPTOSIS REGULATOR BAX, APOPTOSIS REGULATOR BCL-2 | Authors: | Ku, B, Oh, B.H. | Deposit date: | 2010-03-25 | Release date: | 2010-11-24 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Evidence that Inhibition of Bax Activation by Bcl- 2 Involves its Tight and Preferential Interaction with the Bh3 Domain of Bax. Cell Res., 21, 2011
|
|
2WWZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2wwz by Molmil](/molmil-images/mine/2wwz) | TAB2 NZF DOMAIN IN COMPLEX WITH Lys63-linked di-ubiquitin, P212121 | Descriptor: | MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 7-INTERACTING PROTEIN 2, UBIQUITIN, ZINC ION | Authors: | Kulathu, Y, Akutsu, M, Bremm, A, Hofmann, K, Komander, D. | Deposit date: | 2009-10-30 | Release date: | 2009-11-24 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Two-Sided Ubiquitin Binding Explains Specificity of the Tab2 Nzf Domain Nat.Struct.Mol.Biol., 16, 2009
|
|
6JJY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6jjy by Molmil](/molmil-images/mine/6jjy) | Crystal Structure of KIBRA and beta-Dystroglycan | Descriptor: | Peptide from Dystroglycan, Protein KIBRA, SULFATE ION | Authors: | Lin, Z, Yang, Z, Ji, Z, Zhang, M. | Deposit date: | 2019-02-27 | Release date: | 2019-09-25 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.298 Å) | Cite: | Decoding WW domain tandem-mediated target recognitions in tissue growth and cell polarity. Elife, 8, 2019
|
|
3LIM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3lim by Molmil](/molmil-images/mine/3lim) | Crystal structure of the pore forming toxin frac from sea anemone actinia fragacea | Descriptor: | Fragaceatoxin C, LAURYL DIMETHYLAMINE-N-OXIDE | Authors: | Mechaly, A.E, Bellomio, A, Morante, K, Gonzalez-Manas, J.M, Guerin, D.M.A. | Deposit date: | 2010-01-25 | Release date: | 2010-12-15 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural insights into the oligomerization and architecture of eukaryotic membrane pore-forming toxins. Structure, 19, 2011
|
|
2WIT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2wit by Molmil](/molmil-images/mine/2wit) | CRYSTAL STRUCTURE OF THE SODIUM-COUPLED GLYCINE BETAINE SYMPORTER BETP FROM CORYNEBACTERIUM GLUTAMICUM WITH BOUND SUBSTRATE | Descriptor: | GLYCINE BETAINE TRANSPORTER BETP, TRIMETHYL GLYCINE | Authors: | Ressl, S, Terwisscha Van Scheltinga, A.C, Vonrhein, C, Ott, V, Ziegler, C. | Deposit date: | 2009-05-17 | Release date: | 2009-05-26 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.35 Å) | Cite: | Molecular Basis of Transport and Regulation in the Na(+)/Betaine Symporter Betp. Nature, 458, 2009
|
|
3LJP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ljp by Molmil](/molmil-images/mine/3ljp) | Crystal structure of choline oxidase V464A mutant | Descriptor: | Choline oxidase, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE | Authors: | Finnegan, S, Agniswamy, J, Weber, I.T, Giovanni, G. | Deposit date: | 2010-01-26 | Release date: | 2010-03-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Role of valine 464 in the flavin oxidation reaction catalyzed by choline oxidase. Biochemistry, 49, 2010
|
|
1WSX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1wsx by Molmil](/molmil-images/mine/1wsx) | Solution structure of MCL-1 | Descriptor: | myeloid cell leukemia sequence 1 | Authors: | Day, C.L, Chen, L, Richardson, S.J, Harrison, P.J, Huang, D.C, Hinds, M.G. | Deposit date: | 2004-11-12 | Release date: | 2004-11-23 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution Structure of Prosurvival Mcl-1 and Characterization of Its Binding by Proapoptotic BH3-only Ligands J.Biol.Chem., 280, 2005
|
|
1X5E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1x5e by Molmil](/molmil-images/mine/1x5e) | The solution structure of the thioredoxin-like domain of human Thioredoxin-related transmembrane protein | Descriptor: | Thioredoxin domain containing protein 1 | Authors: | Tochio, N, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-05-15 | Release date: | 2005-11-15 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | The solution structure of the thioredoxin-like domain of human Thioredoxin-related transmembrane protein To be Published
|
|
3LMV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3lmv by Molmil](/molmil-images/mine/3lmv) | D-Tyr-tRNA(Tyr) Deacylase from plasmodium falciparum in complex with hepes | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, D-tyrosyl-tRNA(Tyr) deacylase, SULFITE ION | Authors: | Manickam, Y, Khan, S, Bhatt, T.K, Sharma, A. | Deposit date: | 2010-02-01 | Release date: | 2010-03-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.833 Å) | Cite: | Structure of D-tyrosyl-tRNATyr deacylase using home-source Cu Kalpha and moderate-quality iodide-SAD data: structural polymorphism and HEPES-bound enzyme states Acta Crystallogr.,Sect.D, 66, 2010
|
|
2R2L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2r2l by Molmil](/molmil-images/mine/2r2l) | Structure of Farnesyl Protein Transferase bound to PB-93 | Descriptor: | FARNESYL DIPHOSPHATE, Farnesyltransferase subunit alpha, Farnesyltransferase subunit beta, ... | Authors: | Strickland, C.O, Voorhis, W. | Deposit date: | 2007-08-27 | Release date: | 2008-03-11 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.23 Å) | Cite: | Efficacy, pharmacokinetics, and metabolism of tetrahydroquinoline inhibitors of Plasmodium falciparum protein farnesyltransferase. Antimicrob.Agents Chemother., 51, 2007
|
|
1WE9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1we9 by Molmil](/molmil-images/mine/1we9) | Solution structure of PHD domain in nucleic acid binding protein-like NP_197993 | Descriptor: | PHD finger family protein, ZINC ION | Authors: | He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2004-05-24 | Release date: | 2004-11-24 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of PHD domain in nucleic acid binding protein-like NP_197993 To be Published
|
|
6IYU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6iyu by Molmil](/molmil-images/mine/6iyu) | Crystal Structure Analysis of an Eukaryotic Membrane Protein | Descriptor: | CALCIUM ION, CHLORIDE ION, Trimeric intracellular cation channel type A | Authors: | Wang, X.H, Zeng, Y, Su, M, Gao, F, Chen, Y.H. | Deposit date: | 2018-12-17 | Release date: | 2019-05-01 | Last modified: | 2019-11-06 | Method: | X-RAY DIFFRACTION (2.199 Å) | Cite: | Structural basis for activity of TRIC counter-ion channels in calcium release. Proc.Natl.Acad.Sci.USA, 116, 2019
|
|
2QWB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qwb by Molmil](/molmil-images/mine/2qwb) | |
6IZ1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6iz1 by Molmil](/molmil-images/mine/6iz1) | Crystal Structure Analysis of a Eukaryotic Membrane Protein | Descriptor: | CALCIUM ION, CHLORIDE ION, Trimeric intracellular cation channel type A | Authors: | Wang, X.H, Zeng, Y, Gao, F, Su, M, Chen, Y.H. | Deposit date: | 2018-12-18 | Release date: | 2019-05-01 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.399 Å) | Cite: | Structural basis for activity of TRIC counter-ion channels in calcium release. Proc.Natl.Acad.Sci.USA, 116, 2019
|
|
2QFI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qfi by Molmil](/molmil-images/mine/2qfi) | Structure of the zinc transporter YiiP | Descriptor: | Ferrous-iron efflux pump fieF, ZINC ION | Authors: | Lu, M. | Deposit date: | 2007-06-27 | Release date: | 2007-10-16 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Structure of the zinc transporter YiiP. Science, 317, 2007
|
|
3LP1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3lp1 by Molmil](/molmil-images/mine/3lp1) | HIV-1 reverse transcriptase with inhibitor | Descriptor: | 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE, 3-cyclopentyl-1,4-dihydroxy-1,8-naphthyridin-2(1H)-one, MANGANESE (II) ION, ... | Authors: | Yan, Y, Munshi, S.K, Prasad, G.S, Su, H.P. | Deposit date: | 2010-02-04 | Release date: | 2010-06-09 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.23 Å) | Cite: | Structural basis for the inhibition of RNase H activity of HIV-1 reverse transcriptase by RNase H active site-directed inhibitors. J.Virol., 84, 2010
|
|
3LPF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3lpf by Molmil](/molmil-images/mine/3lpf) | Structure of E. coli beta-Glucuronidase bound with a novel, potent inhibitor 1-((6,7-dimethyl-2-oxo-1,2-dihydroquinolin-3-yl)methyl)-1-(2-hydroxyethyl)-3-(3-methoxyphenyl)thiourea | Descriptor: | 1-[(6,7-dimethyl-2-oxo-1,2-dihydroquinolin-3-yl)methyl]-1-(2-hydroxyethyl)-3-(3-methoxyphenyl)thiourea, Beta-glucuronidase | Authors: | Wallace, B.D, Redinbo, M.R. | Deposit date: | 2010-02-05 | Release date: | 2010-11-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | Alleviating cancer drug toxicity by inhibiting a bacterial enzyme. Science, 330, 2010
|
|
6JPF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6jpf by Molmil](/molmil-images/mine/6jpf) | |
1X09
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1x09 by Molmil](/molmil-images/mine/1x09) | Crystal structure of the D26A mutant UPPs in complex with magnesium and isopentenyl pyrophosphate | Descriptor: | 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, MAGNESIUM ION, Undecaprenyl pyrophosphate synthetase | Authors: | Guo, R.-T, Ko, T.-P, Chen, A.P.-C, Kuo, C.-J, Wang, A.H.-J, Liang, P.-H. | Deposit date: | 2005-03-15 | Release date: | 2005-03-22 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Crystal structures of undecaprenyl pyrophosphate synthase in complex with magnesium, isopentenyl pyrophosphate, and farnesyl thiopyrophosphate: roles of the metal ion and conserved residues in catalysis. J.Biol.Chem., 280, 2005
|
|
8JUN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8jun by Molmil](/molmil-images/mine/8jun) | Cryo-EM structure of SIDT1 E555Q mutant | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SID1 transmembrane family member 1, ZINC ION | Authors: | Sun, C.R, Xu, D, Li, Q, Zhou, C.Z, Chen, Y. | Deposit date: | 2023-06-26 | Release date: | 2023-11-15 | Last modified: | 2024-01-24 | Method: | ELECTRON MICROSCOPY (2.38 Å) | Cite: | Human SIDT1 mediates dsRNA uptake via its phospholipase activity. Cell Res., 34, 2024
|
|
2QJY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qjy by Molmil](/molmil-images/mine/2qjy) | Crystal structure of rhodobacter sphaeroides double mutant with stigmatellin and UQ2 | Descriptor: | (1R)-2-{[(R)-(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(DODECANOYLOXY)METHYL]ETHYL (9Z)-OCTADEC-9-ENOATE, 2-O-octyl-beta-D-glucopyranose, CHLORIDE ION, ... | Authors: | Esser, L, Xia, D. | Deposit date: | 2007-07-09 | Release date: | 2007-12-25 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Inhibitor-complexed Structures of the Cytochrome bc1 from the Photosynthetic Bacterium Rhodobacter sphaeroides. J.Biol.Chem., 283, 2008
|
|