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1NJ9
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Cocaine hydrolytic antibody 15A10
Descriptor: SODIUM ION, immunoglobulin heavy chain, immunoglobulin variable chain
Authors:Larsen, N.A, de Prada, P, Deng, S.X, Zhu, X, Landry, D.W, Wilson, I.A.
Deposit date:2002-12-30
Release date:2004-02-17
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystallographic and biochemical analysis of cocaine-degrading antibody 15A10.
Biochemistry, 43, 2004
8F6O
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BU of 8f6o by Molmil
anti-BTLA monoclonal antibody h22B3 in complex with BTLA
Descriptor: B- and T-lymphocyte attenuator, h22B3 Fab heavy chain, h22B3 Fab light chain
Authors:Hendle, J, Atwell, S, Lieu, R, Hickey, M, Weichert, K.
Deposit date:2022-11-16
Release date:2023-05-24
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Epitope topography of agonist antibodies to the checkpoint inhibitory receptor BTLA.
Structure, 31, 2023
3BD3
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BU of 3bd3 by Molmil
Crystal structure of single domain VL of an anti-DNA binding antibody 3D8 scFv and its active site revealed by complex structures of a small molecule and metals
Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, catalytic antibody
Authors:Park, S.K, Kim, J.S.
Deposit date:2007-11-14
Release date:2008-04-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of single-domain VL of an anti-DNA binding antibody 3D8 scFv and its active site revealed by complex structures of a small molecule and metals
Proteins, 71, 2008
4DN3
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BU of 4dn3 by Molmil
Crystal structure of anti-mcp-1 antibody cnto888
Descriptor: CNTO888 HEAVY CHAIN, CNTO888 LIGHT CHAIN
Authors:Obmolova, G, Teplyakov, A, Malia, T, Grygiel, T, Sweet, R, Snyder, L, Gilliland, G.
Deposit date:2012-02-08
Release date:2012-10-03
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for high selectivity of anti-CCL2 neutralizing antibody CNTO 888.
Mol.Immunol., 51, 2012
3EO0
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BU of 3eo0 by Molmil
Structure of the Transforming Growth Factor-Beta Neutralizing Antibody GC-1008
Descriptor: GC-1008 Fab Heavy Chain, GC-1008 Fab Light Chain, GLYCEROL
Authors:Gruetter, C, Gruetter, M.G.
Deposit date:2008-09-26
Release date:2008-12-02
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:A cytokine-neutralizing antibody as a structural mimetic of 2 receptor interactions
Proc.Natl.Acad.Sci.Usa, 105, 2008
2IGF
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BU of 2igf by Molmil
CRYSTAL STRUCTURES OF AN ANTIBODY TO A PEPTIDE AND ITS COMPLEX WITH PEPTIDE ANTIGEN AT 2.8 ANGSTROMS
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, IGG1-KAPPA B13I2 FAB (HEAVY CHAIN), IGG1-KAPPA B13I2 FAB (LIGHT CHAIN), ...
Authors:Stanfield, R.L, Wilson, I.A.
Deposit date:1991-03-21
Release date:1992-04-15
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures of an antibody to a peptide and its complex with peptide antigen at 2.8 A.
Science, 248, 1990
7RYV
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BU of 7ryv by Molmil
Anti-HIV neutralizing antibody Ab1573 Fab isolated from sequentially immunized macaques
Descriptor: Ab1573 Fab heavy chain, Ab1573 Fab light chain
Authors:Yang, Z, Bjorkman, P.J.
Deposit date:2021-08-26
Release date:2022-01-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Neutralizing antibodies induced in immunized macaques recognize the CD4-binding site on an occluded-open HIV-1 envelope trimer.
Nat Commun, 13, 2022
7RYU
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BU of 7ryu by Molmil
Anti-HIV neutralizing antibody Ab1303 Fab isolated from sequentially immunized mcaques
Descriptor: Ab1303 Fab heavy chain, Ab1303 Fab light chain
Authors:Yang, Z, Bjorkman, P.J.
Deposit date:2021-08-26
Release date:2022-01-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Neutralizing antibodies induced in immunized macaques recognize the CD4-binding site on an occluded-open HIV-1 envelope trimer.
Nat Commun, 13, 2022
7S5P
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BU of 7s5p by Molmil
Crystal structure of SARS-CoV-2 B.1.351 variant receptor binding domain in complex with neutralizing antibody CS23
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CS23 Heavy chain, ...
Authors:Yuan, M, Wilson, I.A.
Deposit date:2021-09-11
Release date:2022-03-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:SARS-CoV-2 Beta variant infection elicits potent lineage-specific and cross-reactive antibodies.
Science, 375, 2022
7X7O
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BU of 7x7o by Molmil
SARS-CoV-2 spike RBD in complex with neutralizing antibody UT28K
Descriptor: Spike protein S1, UT28K Fab, heavy chain, ...
Authors:Ozawa, T, Tani, H, Anraku, Y, Kita, S, Igarashi, E, Saga, Y, Inasaki, N, Kawasuji, H, Yamada, H, Sasaki, S, Somekawa, M, Sasaki, J, Hayakawa, Y, Yamamoto, Y, Morinaga, Y, Kurosawa, N, Isobe, M, Fukuhara, H, Maenaka, K, Hashiguchi, T, Kishi, H, Kitajima, I, Saito, S, Niimi, H.
Deposit date:2022-03-10
Release date:2022-05-25
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.75 Å)
Cite:Novel super-neutralizing antibody UT28K is capable of protecting against infection from a wide variety of SARS-CoV-2 variants.
Mabs, 14, 2022
6FYT
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BU of 6fyt by Molmil
Structure of H1 (A/solomon Islands/3/06) Influenza Hemagglutinin in complex with SD38
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:Laursen, N.S, Wilson, I.A.
Deposit date:2018-03-12
Release date:2018-11-07
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin.
Science, 362, 2018
2V7N
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BU of 2v7n by Molmil
Unusual twinning in crystals of the CitS binding antibody Fab fragment f3p4
Descriptor: IMMUNOGLOBULIN HEAVY CHAIN, IMMUNOGLOBULIN LIGHT CHAIN
Authors:Frey, D, Huber, T, Plueckthun, A, Gruetter, M.G.
Deposit date:2007-07-31
Release date:2008-06-17
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structure of the Recombinant Antibody Fab Fragment F3P4.
Acta Crystallogr.,Sect.D, 64, 2008
2QQN
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BU of 2qqn by Molmil
Neuropilin-1 b1 Domain in Complex with a VEGF-Blocking Fab
Descriptor: 1,2-ETHANEDIOL, Antibody heavy chain, Antibody light chain, ...
Authors:Appleton, B.A, Wiesmann, C.
Deposit date:2007-07-26
Release date:2007-11-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding
Embo J., 26, 2007
6FYU
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BU of 6fyu by Molmil
Structure of H7(A/Shanghai/2/2013) Influenza Hemagglutinin in complex SD36
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:Laursen, N.S, Wilson, I.A.
Deposit date:2018-03-12
Release date:2018-11-07
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.643 Å)
Cite:Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin.
Science, 362, 2018
4RNR
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BU of 4rnr by Molmil
Crystal structure of broadly neutralizing anti-HIV antibody PGT130
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, PGT130 Heavy Chain, PGT130 Light Chain
Authors:Kong, L, Wilson, I.A.
Deposit date:2014-10-24
Release date:2014-11-19
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.758 Å)
Cite:Two Classes of Broadly Neutralizing Antibodies within a Single Lineage Directed to the High-Mannose Patch of HIV Envelope.
J.Virol., 89, 2015
5Y2K
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BU of 5y2k by Molmil
A human antibody AF4H1L1
Descriptor: a group 2 HA binding antibody AF4H1K1 Fab heavy chain, a group 2 HA binding antibody AF4H1K1 Fab light chain
Authors:Xiao, H, Qi, J, Gao, F.G.
Deposit date:2017-07-26
Release date:2019-01-30
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:An H3-clade neutralizing antibody screened from an H7N9 patient that binds group 2 influenza A hemagglutinins
To Be Published
5Y2M
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BU of 5y2m by Molmil
Crystal structure of a group 2 HA binding antibody AF4H1K1 Fab in complex with the H4N6 duck isolate (H4-CZ/56) hemagglutinin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, a group 2 HA binding antibody AF4H1K1 Fab heavy chain, ...
Authors:Xiao, H, Qi, J, Gao, F.G.
Deposit date:2017-07-26
Release date:2019-02-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:An H3-clade neutralizing antibody screened from an H7N9 patient that binds group 2 influenza A hemagglutinins
To Be Published
2GKI
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BU of 2gki by Molmil
Heavy and light chain variable single domains of an anti-DNA binding antibody hydrolyze both double- and single-stranded DNAs without sequence specificity
Descriptor: nuclease
Authors:Kim, Y.R, Kim, J.S, Lee, S.H, Lee, W.R, Sohn, J.N, Chung, Y.C, Shim, H.K, Lee, S.C, Kwon, M.H, Kim, Y.S.
Deposit date:2006-04-02
Release date:2006-04-18
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.88 Å)
Cite:Heavy and light chain variable single domains of an anti-DNA binding antibody hydrolyze both double- and single-stranded DNAs without sequence specificity.
J.Biol.Chem., 281, 2006
8DZV
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BU of 8dzv by Molmil
Chicken anti-cardiac Troponin I antibody in complex with peptide
Descriptor: PHOSPHATE ION, POTASSIUM ION, cTnI peptide, ...
Authors:Conroy, P.J, Law, H.P.
Deposit date:2022-08-08
Release date:2023-07-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Design of Polarity-Dependent Immunosensors Based on the Structural Analysis of Engineered Antibodies.
Acs Chem.Biol., 18, 2023
4U7S
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BU of 4u7s by Molmil
Homodimeric Single Domain Antibody (sdAb) against Staphylococcal enterotoxin B (SEB) Crystallized for 5 months
Descriptor: SULFATE ION, sdAb A3
Authors:Legler, P.M.
Deposit date:2014-07-31
Release date:2014-09-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Structural and mutational analysis of a monomeric and dimeric form of a single domain antibody with implications for protein misfolding.
Proteins, 82, 2014
5ZUF
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BU of 5zuf by Molmil
Fit R10 Fab coordinates into the cryo-EM of EV71 in complex with A9
Descriptor: Capsid protein VP1, R10 ANTIBODY HEAVY CHAIN, R10 ANTIBODY LIGHT CHAIN, ...
Authors:Wang, X, Zhu, L, Wang, N.
Deposit date:2018-05-07
Release date:2019-12-25
Last modified:2021-01-06
Method:ELECTRON MICROSCOPY (6.8 Å)
Cite:Neutralization Mechanisms of Two Highly Potent Antibodies against Human Enterovirus 71.
Mbio, 9, 2018
7YMS
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BU of 7yms by Molmil
Cryo-EM structure of Coxsackievirus A16 in complex with a neutralizing antibody 9B5
Descriptor: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
Authors:Cong, Y, Liu, C.X.
Deposit date:2022-07-29
Release date:2022-08-24
Last modified:2023-03-15
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Molecular mechanism of antibody neutralization of coxsackievirus A16.
Nat Commun, 13, 2022
2D7T
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BU of 2d7t by Molmil
Crystal structure of human anti polyhydroxybutyrate antibody Fv
Descriptor: anti polyhydroxybutyrate antibody Fv, heavy chain, light chain
Authors:Watanabe, H.
Deposit date:2005-11-29
Release date:2006-12-12
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A human antibody fragment with high affinity for the biodegradable polymer film
To be Published
6XPX
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BU of 6xpx by Molmil
Human antibody S1V2-51 in complex with the influenza hemagglutinin head domain of A/Aichi/2/1968 (X-31)(H3N2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, BICINE, GLYCEROL, ...
Authors:McCarthy, K.R, Harrison, S.C.
Deposit date:2020-07-09
Release date:2021-05-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.598 Å)
Cite:A Prevalent Focused Human Antibody Response to the Influenza Virus Hemagglutinin Head Interface.
Mbio, 12, 2021
7S13
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BU of 7s13 by Molmil
Crystal structure of Fab in complex with mouse CD96 dimer
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CITRATE ANION, ...
Authors:Lee, P.S, Barman, I, Strop, P.
Deposit date:2021-08-31
Release date:2021-10-20
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Antibody blockade of CD96 by distinct molecular mechanisms.
Mabs, 13, 2021

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