7X7O

SARS-CoV-2 spike RBD in complex with neutralizing antibody UT28K

Summary for 7X7O

Entry DOI	10.2210/pdb7x7o/pdb
Descriptor	Spike protein S1, UT28K Fab, heavy chain, UT28K Fab, light chain (3 entities in total)
Functional Keywords	sars-cov-2, spike, antibody, viral protein
Biological source	Severe acute respiratory syndrome coronavirus 2 More
Total number of polymer chains	12
Total formula weight	310251.80
Authors	Ozawa, T.,Tani, H.,Anraku, Y.,Kita, S.,Igarashi, E.,Saga, Y.,Inasaki, N.,Kawasuji, H.,Yamada, H.,Sasaki, S.,Somekawa, M.,Sasaki, J.,Hayakawa, Y.,Yamamoto, Y.,Morinaga, Y.,Kurosawa, N.,Isobe, M.,Fukuhara, H.,Maenaka, K.,Hashiguchi, T.,Kishi, H.,Kitajima, I.,Saito, S.,Niimi, H. (deposition date: 2022-03-10, release date: 2022-05-25, Last modification date: 2023-11-29)
Primary citation	Ozawa, T.,Tani, H.,Anraku, Y.,Kita, S.,Igarashi, E.,Saga, Y.,Inasaki, N.,Kawasuji, H.,Yamada, H.,Sasaki, S.I.,Somekawa, M.,Sasaki, J.,Hayakawa, Y.,Yamamoto, Y.,Morinaga, Y.,Kurosawa, N.,Isobe, M.,Fukuhara, H.,Maenaka, K.,Hashiguchi, T.,Kishi, H.,Kitajima, I.,Saito, S.,Niimi, H. Novel super-neutralizing antibody UT28K is capable of protecting against infection from a wide variety of SARS-CoV-2 variants. Mabs, 14:2072455-2072455, 2022 Cited by PubMed: 35543180 DOI: 10.1080/19420862.2022.2072455 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.75 Å)

Structure validation