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4YCU
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BU of 4ycu by Molmil
Crystal structure of cladosporin in complex with human lysyl-tRNA synthetase
Descriptor: Aminoacyl tRNA synthase complex-interacting multifunctional protein 2, GLYCEROL, LYSINE, ...
Authors:Fang, P, Wang, J, Guo, M.
Deposit date:2015-02-20
Release date:2015-06-10
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Basis for Specific Inhibition of tRNA Synthetase by an ATP Competitive Inhibitor.
Chem. Biol., 22, 2015
6HHV
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BU of 6hhv by Molmil
Structure of T. thermophilus AspRS in Complex with 5'-O-(N-(L-aspartyl)-sulfamoyl)N3-methyluridine
Descriptor: 5'-O-(N-(L-aspartyl)-sulfamoyl)N3-methyluridine, Aspartate--tRNA(Asp) ligase
Authors:De Graef, S, Pang, L, Strelkov, S.V, Weeks, S.D.
Deposit date:2018-08-29
Release date:2019-12-18
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Structural Insights into the Binding of Natural Pyrimidine-Based Inhibitors of Class II Aminoacyl-tRNA Synthetases.
Acs Chem.Biol., 15, 2020
6HHX
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BU of 6hhx by Molmil
Structure of T. thermophilus AspRS in Complex with 5'-O-(N-(L-aspartyl)-sulfamoyl)cytidine
Descriptor: 5'-O-(N-(L-aspartyl)-sulfamoyl)cytidine, Aspartate--tRNA(Asp) ligase
Authors:De Graef, S, Pang, L, Strelkov, S.V, Weeks, S.D.
Deposit date:2018-08-29
Release date:2019-12-18
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Insights into the Binding of Natural Pyrimidine-Based Inhibitors of Class II Aminoacyl-tRNA Synthetases.
Acs Chem.Biol., 15, 2020
1RRD
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BU of 1rrd by Molmil
DNA/RNA HYBRID DUPLEX CONTAINING A PURINE-RICH RNA STRAND, NMR, 10 STRUCTURES
Descriptor: DNA (5'-D(*GP*CP*TP*TP*CP*TP*CP*TP*TP*C)-3'), RNA (5'-R(*GP*AP*AP*GP*AP*GP*AP*AP*GP*C)-3')
Authors:Gyi, J.I, Lane, A.N, Conn, G.L, Brown, T.
Deposit date:1997-10-21
Release date:1998-04-22
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structures of DNA.RNA hybrids with purine-rich and pyrimidine-rich strands: comparison with the homologous DNA and RNA duplexes.
Biochemistry, 37, 1998
7V9D
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BU of 7v9d by Molmil
Plasmodium falciparum Prolyl-tRNA Synthetase (PfPRS) in Complex with inhibitor L95 and azetidine
Descriptor: (2S)-azetidine-2-carboxylic acid, 1,2-ETHANEDIOL, 1,4-BUTANEDIOL, ...
Authors:Manickam, Y, Malhotra, N, Sharma, A.
Deposit date:2021-08-24
Release date:2022-09-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.937 Å)
Cite:Plasmodium falciparum Prolyl-tRNA Synthetase (PfPRS) in Complex with inhibitor L95 and azetidine
To Be Published
6IX6
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BU of 6ix6 by Molmil
Crystal structure of the complex of peptidyl-tRNA hydrolase with N-propanol at 1.43 A resolution
Descriptor: N-PROPANOL, Peptidyl-tRNA hydrolase
Authors:Viswanathan, V, Sharma, P, Chaudhary, A, Sharma, S, Singh, T.P.
Deposit date:2018-12-09
Release date:2018-12-26
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Crystal structure of the complex of peptidyl-tRNA hydrolase with N-propanol at 1.43 A resolution
To Be Published
4XKZ
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BU of 4xkz by Molmil
Crystal structure of the C-terminal anticodon loop binding domain of a valyl-tRNA synthetase from Pseudomonas aeruginosa
Descriptor: IODIDE ION, TRIETHYLENE GLYCOL, Valine-tRNA ligase
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2015-01-12
Release date:2015-02-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of the C-terminal anticodon loop binding domain of a valyl-tRNA synthetase from Pseudomonas aeruginosa.
To Be Published
6JKX
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BU of 6jkx by Molmil
Crystal structure of peptidyl-tRNA hydrolase with multiple sodium and chloride ions at 1.08 A resolution.
Descriptor: CHLORIDE ION, METHANOL, Peptidyl-tRNA hydrolase, ...
Authors:Viswanathan, V, Sharma, P, Bhushan, A, Sharma, S, Singh, T.P.
Deposit date:2019-03-03
Release date:2019-03-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.08 Å)
Cite:Crystal structure of peptidyl-tRNA hydrolase with multiple sodium and chloride ions at 1.08 A resolution.
To Be Published
6JJ1
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BU of 6jj1 by Molmil
Crystal structure of peptidyl-tRNA hydrolase from Acinetobacter baumannii at 0.97 A resolution with disordered five N-terminal residues
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Peptidyl-tRNA hydrolase
Authors:Iqbal, N, Sharma, P, Chaudhary, A, Sharma, S, Singh, T.P.
Deposit date:2019-02-24
Release date:2019-03-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (0.97 Å)
Cite:Crystal structure of peptidyl-tRNA hydrolase from Acinetobacter baumannii at 0.97 A resolution with disordered five N-terminal residues
To Be Published
8C49
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BU of 8c49 by Molmil
Crystal structure of pyrrolysyl-tRNA synthetase from Methanomethylophilus alvus engineered for 3-Methyl-L-histidine, bound to AMPPNP
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ...
Authors:Hardy, F.J, Levy, C.W.
Deposit date:2023-01-03
Release date:2023-07-19
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Engineering mutually orthogonal PylRS/tRNA pairs for dual encoding of functional histidine analogues.
Protein Sci., 32, 2023
6JJQ
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BU of 6jjq by Molmil
Crystal structure of peptidyl-tRNA hydrolase from Acinetobacter baumannii at 0.99 A resolution.
Descriptor: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Peptidyl-tRNA hydrolase, ...
Authors:Viswanathan, V, Bairagya, H.R, Sharma, P, Sharma, S, Singh, T.P.
Deposit date:2019-02-26
Release date:2019-03-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (0.99 Å)
Cite:Crystal structure of peptidyl-tRNA hydrolase from Acinetobacter baumannii at 0.99 A resolution.
To Be Published
7V8K
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BU of 7v8k by Molmil
Toxoplasma gondii Prolyl-tRNA Synthetase (TgPRS) in Complex with L-Proline
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, IMIDAZOLE, ...
Authors:Manickam, Y, Malhotra, N, Sharma, A.
Deposit date:2021-08-23
Release date:2022-09-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:Toxoplasma gondii Prolyl-tRNA Synthetase (TgPRS) in Complex with L-Proline
To Be Published
7V8J
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BU of 7v8j by Molmil
Toxoplasma gondii Prolyl-tRNA Synthetase (TgPRS) in complex with the reaction intermediates proline-adenylate (Pro-AMP) and pyrophosphate
Descriptor: 1,2-ETHANEDIOL, 5'-O-[(R)-hydroxy{[(2S)-pyrrolidin-2-ylcarbonyl]oxy}phosphoryl]adenosine, PROLINE, ...
Authors:Manickam, Y, Malhotra, N, Sharma, A.
Deposit date:2021-08-23
Release date:2022-09-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.519 Å)
Cite:Toxoplasma gondii Prolyl-tRNA Synthetase (TgPRS) in complex with the reaction intermediates proline-adenylate (Pro-AMP) and pyrophosphate
To Be Published
5BMU
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BU of 5bmu by Molmil
The crystal structure of the GST-like domains complex of AIMP3-EPRS mutant C92SC105SC123S
Descriptor: Eukaryotic translation elongation factor 1 epsilon-1, Glutamate--tRNA ligase
Authors:Cho, H.J, Kang, B.S.
Deposit date:2015-05-23
Release date:2015-10-21
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Assembly of Multi-tRNA Synthetase Complex via Heterotetrameric Glutathione Transferase-homology Domains
J.Biol.Chem., 290, 2015
259D
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BU of 259d by Molmil
RNA HYDRATION: A DETAILED LOOK
Descriptor: RNA (5'-R(*CP*CP*CP*CP*GP*GP*GP*G)-3')
Authors:Egli, M, Portmann, S, Usman, N.
Deposit date:1996-05-03
Release date:1996-08-26
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:RNA hydration: a detailed look.
Biochemistry, 35, 1996
3CR1
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BU of 3cr1 by Molmil
crystal structure of a minimal, mutant, all-RNA hairpin ribozyme (A38C, A-1OMA) grown from MgCl2
Descriptor: MAGNESIUM ION, RNA (5'-R(*UP*CP*CP*CP*(A2M)P*GP*UP*CP*CP*AP*CP*CP*G)-3'), RNA (5'-R(*UP*CP*GP*UP*GP*GP*UP*CP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3'), ...
Authors:Salter, J.D, Wedekind, J.E.
Deposit date:2008-04-04
Release date:2008-08-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural effects of nucleobase variations at key active site residue Ade38 in the hairpin ribozyme.
Rna, 14, 2008
2OUE
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BU of 2oue by Molmil
Crystal structure of a junctionless all-RNA hairpin ribozyme at 2.05 angstroms resolution
Descriptor: COBALT HEXAMMINE(III), Loop A ribozyme strand, Loop B S-turn strand, ...
Authors:Wedekind, J.E.
Deposit date:2007-02-10
Release date:2007-03-06
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Water in the Active Site of an All-RNA Hairpin Ribozyme and Effects of Gua8 Base Variants on the Geometry of Phosphoryl Transfer.
Biochemistry, 45, 2006
7EIV
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BU of 7eiv by Molmil
heterotetrameric glycyl-tRNA synthetase from Escherichia coli
Descriptor: GLYCINE, Glycine--tRNA ligase alpha subunit, Glycine--tRNA ligase beta subunit, ...
Authors:Ju, Y, Zhou, H.
Deposit date:2021-03-31
Release date:2021-08-11
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:X-shaped structure of bacterial heterotetrameric tRNA synthetase suggests cryptic prokaryote functions and a rationale for synthetase classifications.
Nucleic Acids Res., 49, 2021
8D5J
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BU of 8d5j by Molmil
The complex of Pre-mRNA-Processing Factor 19 (Prpf19) neoantigen KYLQVASHV Presented by H2-Kd
Descriptor: Beta-2-microglobulin, MHC class I heavy chain maturation peptide H-2K(D), Pre-mRNA-processing factor 19
Authors:Custodio, J.M.F, Baker, B.M.
Deposit date:2022-06-04
Release date:2022-07-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The complex of Pre-mRNA-Processing Factor 19 (Prpf19) neoantigen KYLQVASHV Presented by H2-Kd
To Be Published
5IVP
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BU of 5ivp by Molmil
Crystal structure of the Peptidyl-tRNA hydrolase from Vibrio cholerae in the C121 space group at pH 6.5
Descriptor: CITRATE ANION, Peptidyl-tRNA hydrolase
Authors:Shahid, S, Kabra, A, Pal, R.K, Arora, A.
Deposit date:2016-03-21
Release date:2017-03-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Crystal structure of the Peptidyl-tRNA hydrolase from Vibrio cholerae in the C121 space group at pH 6.5
To Be Published
2O5R
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BU of 2o5r by Molmil
Crystal structure of Glutamyl-tRNA synthetase 1 (EC 6.1.1.17) (Glutamate-tRNA ligase 1) (GluRS 1) (TM1351) from Thermotoga maritima at 2.5 A resolution
Descriptor: CHLORIDE ION, GLYCEROL, Glutamyl-tRNA synthetase 1
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2006-12-06
Release date:2006-12-19
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Crystal structure of Glutamyl-tRNA synthetase 1 (EC 6.1.1.17) (Glutamate-tRNA ligase 1) (GluRS 1) (TM1351) from Thermotoga maritima at 2.5 A resolution
To be published
5V58
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BU of 5v58 by Molmil
Crystal structure of human prolyl-tRNA synthetase in complex with Aze-SA
Descriptor: 5'-O-{[(2S)-azetidine-2-carbonyl]sulfamoyl}adenosine, Bifunctional glutamate/proline--tRNA ligase, ZINC ION
Authors:Zhou, H, Song, Y, Schimmel, P.
Deposit date:2017-03-13
Release date:2018-01-10
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Double mimicry evades tRNA synthetase editing by toxic vegetable-sourced non-proteinogenic amino acid.
Nat Commun, 8, 2017
6WBD
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BU of 6wbd by Molmil
Crystal Structure of Lysyl-tRNA synthetase from Stenotrophomonas maltophilia with bound L-lysine
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, LYSINE, ...
Authors:Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2020-03-26
Release date:2020-04-08
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal Structure of Lysyl-tRNA synthetase from Stenotrophomonas maltophilia with bound L-lysine
to be published
3QO8
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BU of 3qo8 by Molmil
Crystal Structure of seryl-tRNA synthetase from Candida albicans
Descriptor: 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, MAGNESIUM ION, Seryl-tRNA synthetase, ...
Authors:Rocha, R, Santos, M.A, Pereira, P.J.B, Macedo-Ribeiro, S.
Deposit date:2011-02-09
Release date:2011-08-03
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Unveiling the structural basis for translational ambiguity tolerance in a human fungal pathogen.
Proc.Natl.Acad.Sci.USA, 108, 2011
6VU9
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BU of 6vu9 by Molmil
Crystal structure of threonyl-tRNA synthetase (ThrRS) from Stenotrophomonas maltophilia K279a
Descriptor: SULFATE ION, Threonine--tRNA ligase, ZINC ION
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2020-02-14
Release date:2020-03-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of threonyl-tRNA synthetase (ThrRS) from Stenotrophomonas maltophilia K279a
To Be Published

222415

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