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8QXM
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BU of 8qxm by Molmil
Cryo-EM structure of tetrameric human SAMHD1 State III - Relaxed
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, ...
Authors:Acton, O.J, Sheppard, D, Rosenthal, P.B, Taylor, I.A.
Deposit date:2023-10-24
Release date:2024-05-15
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.94 Å)
Cite:Platform-directed allostery and quaternary structure dynamics of SAMHD1 catalysis.
Nat Commun, 15, 2024
8QXN
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BU of 8qxn by Molmil
Cryo-EM structure of tetrameric human SAMHD1 State IV - Depleted relaxed
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, ...
Authors:Acton, O.J, Sheppard, D, Rosenthal, P.B, Taylor, I.A.
Deposit date:2023-10-24
Release date:2024-05-15
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.98 Å)
Cite:Platform-directed allostery and quaternary structure dynamics of SAMHD1 catalysis.
Nat Commun, 15, 2024
8QXK
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BU of 8qxk by Molmil
Cryo-EM structure of tetrameric human SAMHD1 State I - Tense
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, ...
Authors:Acton, O.J, Sheppard, D, Rosenthal, P.B, Taylor, I.A.
Deposit date:2023-10-24
Release date:2024-05-15
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.66 Å)
Cite:Platform-directed allostery and quaternary structure dynamics of SAMHD1 catalysis.
Nat Commun, 15, 2024
8QXO
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BU of 8qxo by Molmil
Cryo-EM structure of tetrameric human SAMHD1 State V - Depleted relaxed
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, ...
Authors:Acton, O.J, Sheppard, D, Rosenthal, P.B, Taylor, I.A.
Deposit date:2023-10-24
Release date:2024-05-15
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.43 Å)
Cite:Platform-directed allostery and quaternary structure dynamics of SAMHD1 catalysis.
Nat Commun, 15, 2024
1C9B
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BU of 1c9b by Molmil
CRYSTAL STRUCTURE OF A HUMAN TBP CORE DOMAIN-HUMAN TFIIB CORE DOMAIN COMPLEX BOUND TO AN EXTENDED, MODIFIED ADENOVIRAL MAJOR LATE PROMOTER (ADMLP)
Descriptor: ADMLP TATA-BOX DNA CONTAINING IIB RECOGNITION ELEMENT, GENERAL TRANSCRIPTION FACTOR IIB, TATA BOX BINDING PROTEIN
Authors:Tsai, F.T.F, Sigler, P.B.
Deposit date:1999-08-01
Release date:2000-01-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural basis of preinitiation complex assembly on human pol II promoters.
EMBO J., 19, 2000
4AK9
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BU of 4ak9 by Molmil
Structure of chloroplast FtsY from Physcomitrella patens
Descriptor: CPFTSY
Authors:Trager, C, Schunemann, D, Hofmann, E.
Deposit date:2012-02-22
Release date:2013-01-16
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Evolution from the Prokaryotic to the Higher Plant Chloroplast Signal Recognition Particle: The Signal Recognition Particle RNA is Conserved in Plastids of a Wide Range of Photosynthetic Organisms.
Plant Cell, 24, 2012
2NVO
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BU of 2nvo by Molmil
Crystal structure of Deinococcus radiodurans RO (RSR) protein
Descriptor: CALCIUM ION, Ro sixty-related protein, RSR
Authors:Ramesh, A, Sacchettini, J.C.
Deposit date:2006-11-13
Release date:2007-03-27
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Crystal structure of Rsr, an ortholog of the antigenic Ro protein, links conformational flexibility to RNA binding activity.
J.Biol.Chem., 282, 2007
1AN7
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BU of 1an7 by Molmil
RIBOSOMAL PROTEIN S8 FROM THERMUS THERMOPHILUS
Descriptor: RIBOSOMAL PROTEIN S8
Authors:Nevskaya, N, Nikonov, S, Al-Karadaghi, S.
Deposit date:1997-06-27
Release date:1998-07-01
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of ribosomal protein S8 from Thermus thermophilus reveals a high degree of structural conservation of a specific RNA binding site.
J.Mol.Biol., 279, 1998
2B3Y
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BU of 2b3y by Molmil
Structure of a monoclinic crystal form of human cytosolic aconitase (IRP1)
Descriptor: ACETATE ION, FORMIC ACID, GLYCEROL, ...
Authors:Dupuy, J, Fontecilla-Camps, J.C, Volbeda, A.
Deposit date:2005-09-22
Release date:2006-01-10
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of human iron regulatory protein 1 as cytosolic aconitase
Structure, 14, 2006
4IJF
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BU of 4ijf by Molmil
Crystal structure of the Zaire ebolavirus VP35 interferon inhibitory domain K222A/R225A/K248A/K251A mutant
Descriptor: Polymerase cofactor VP35
Authors:Binning, J.B, Wang, T, Leung, D.W, Xu, W, Borek, D, Amarasinghe, G.K.
Deposit date:2012-12-21
Release date:2013-10-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.506 Å)
Cite:Development of RNA Aptamers Targeting Ebola Virus VP35.
Biochemistry, 52, 2013
2P4A
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BU of 2p4a by Molmil
X-ray structure of a camelid affinity matured single-domain vhh antibody fragment in complex with RNASE A
Descriptor: ANTIBODY CAB-RN05, Ribonuclease pancreatic, SULFATE ION
Authors:Tereshko, V, Koide, A, Uysal, S, Koide, S.
Deposit date:2007-03-11
Release date:2007-08-28
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Exploring the capacity of minimalist protein interfaces: interface energetics and affinity maturation to picomolar KD of a single-domain antibody with a flat paratope.
J.Mol.Biol., 373, 2007
2HOH
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BU of 2hoh by Molmil
RIBONUCLEASE T1 (N9A MUTANT) COMPLEXED WITH 2'GMP
Descriptor: CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, PHOSPHATE ION, ...
Authors:Langhorst, U, Loris, R, Denisov, V.P, Doumen, J, Roose, P, Maes, D, Halle, B, Steyaert, J.
Deposit date:1998-09-14
Release date:1998-09-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Dissection of the structural and functional role of a conserved hydration site in RNase T1.
Protein Sci., 8, 1999
2CPJ
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BU of 2cpj by Molmil
Solution structure of the N-terminal RNA recognition motif of NonO
Descriptor: Non-POU domain-containing octamer-binding protein
Authors:Nagata, T, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-05-19
Release date:2005-11-19
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the N-terminal RNA recognition motif of NonO
To be Published
1DMG
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BU of 1dmg by Molmil
CRYSTAL STRUCTURE OF RIBOSOMAL PROTEIN L4
Descriptor: CITRIC ACID, RIBOSOMAL PROTEIN L4
Authors:Worbs, M, Huber, R, Wahl, M.C.
Deposit date:1999-12-14
Release date:2000-12-18
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of ribosomal protein L4 shows RNA-binding sites for ribosome incorporation and feedback control of the S10 operon.
EMBO J., 19, 2000
2P49
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BU of 2p49 by Molmil
Complex of a camelid single-domain vhh antibody fragment with RNASE A at 1.4A resolution: native mono_1 crystal form
Descriptor: ANTIBODY CAB-RN05, PHOSPHATE ION, Ribonuclease pancreatic
Authors:Tereshko, V, Uysal, S, Margalef, K, Koide, A, Kossiakoff, A.A, Koide, S.
Deposit date:2007-03-11
Release date:2007-08-28
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:Exploring the capacity of minimalist protein interfaces: interface energetics and affinity maturation to picomolar KD of a single-domain antibody with a flat paratope.
J.Mol.Biol., 373, 2007
3H5Y
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BU of 3h5y by Molmil
Norovirus polymerase+primer/template+CTP complex at 6 mM MnCl2
Descriptor: 5'-R(*UP*GP*CP*CP*CP*GP*GP*G)-3', 5'-R(P*UP*GP*CP*CP*CP*GP*GP*GP*C)-3', CYTIDINE-5'-TRIPHOSPHATE, ...
Authors:Zamyatkin, D.F, Parra, F, Machin, A, Grochulski, P, Ng, K.K.S.
Deposit date:2009-04-22
Release date:2009-05-19
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Binding of 2'-amino-2'-deoxycytidine-5'-triphosphate to norovirus polymerase induces rearrangement of the active site.
J.Mol.Biol., 390, 2009
3D3Z
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BU of 3d3z by Molmil
Crystal structure of Actibind a T2 RNase
Descriptor: 1,2-ETHANEDIOL, 1-(5-deoxy-beta-L-xylofuranosyl)pyrimidine-2,4(1H,3H)-dione, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Gonzalez, A, Almog, O.
Deposit date:2008-05-13
Release date:2009-06-02
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structue of Actibind a T2 RNase
To be Published
1A32
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BU of 1a32 by Molmil
RIBOSOMAL PROTEIN S15 FROM BACILLUS STEAROTHERMOPHILUS
Descriptor: RIBOSOMAL PROTEIN S15
Authors:Clemons Junior, W.M, Davies, C, White, S.W, Ramakrishnan, V.
Deposit date:1998-01-27
Release date:1998-05-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Conformational variability of the N-terminal helix in the structure of ribosomal protein S15.
Structure, 6, 1998
3EAQ
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BU of 3eaq by Molmil
Novel dimerization motif in the DEAD box RNA helicase Hera form 2, complete dimer, symmetric
Descriptor: CHLORIDE ION, Heat resistant RNA dependent ATPase
Authors:Klostermeier, D, Rudolph, M.G.
Deposit date:2008-08-26
Release date:2008-12-09
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A novel dimerization motif in the C-terminal domain of the Thermus thermophilus DEAD box helicase Hera confers substantial flexibility.
Nucleic Acids Res., 37, 2009
4IN0
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BU of 4in0 by Molmil
Crystal Structure of human splicing factor dim2/TXNL4B
Descriptor: Thioredoxin-like protein 4B, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose
Authors:Jin, T.C, Guo, F, Zhang, Y.Z.
Deposit date:2013-01-03
Release date:2013-03-13
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.327 Å)
Cite:High-resolution crystal structure of human Dim2/TXNL4B.
Acta Crystallogr.,Sect.F, 69, 2013
332D
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BU of 332d by Molmil
CRYSTAL STRUCTURE OF R(GUGUGUA)D(C) WITH TANDEM G-U/U-G WOBBLE PAIRS WITH STRAND SLIPPAGE
Descriptor: DNA/RNA (5'-R(*GP*UP*GP*UP*GP*UP*AP*)-D(*C)-3')
Authors:Biswas, R, Sundaralingam, M.
Deposit date:1997-05-14
Release date:1997-09-23
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Crystal structure of r(GUGUGUA)dC with tandem G x U/U x G wobble pairs with strand slippage.
J.Mol.Biol., 270, 1997
3KCH
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BU of 3kch by Molmil
Baranase crosslinked by glutaraldehyde
Descriptor: PENTANEDIAL, Ribonuclease
Authors:Prange, T, Salem, M, Mauguen, Y.
Deposit date:2009-10-21
Release date:2010-03-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Revisiting glutaraldehyde cross-linking: the case of the Arg-Lys intermolecular doublet
Acta Crystallogr.,Sect.F, 66, 2010
4L3B
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BU of 4l3b by Molmil
X-ray structure of the HRV2 A particle uncoating intermediate
Descriptor: Protein VP1, Protein VP2, Protein VP3
Authors:Vives-Adrian, L, Querol-Audi, J, Garriga, D, Pous, J, Verdaguer, N.
Deposit date:2013-06-05
Release date:2013-11-27
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (6.5 Å)
Cite:Uncoating of common cold virus is preceded by RNA switching as determined by X-ray and cryo-EM analyses of the subviral A-particle.
Proc.Natl.Acad.Sci.USA, 110, 2013
6YWN
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BU of 6ywn by Molmil
CutA in complex with CMPCPP
Descriptor: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, CALCIUM ION, CutA
Authors:Malik, D, Kobylecki, K, Krawczyk, P, Poznanski, J, Jakielaszek, A, Napiorkowska, A, Dziembowski, A, Tomecki, R, Nowotny, M.
Deposit date:2020-04-29
Release date:2020-08-05
Last modified:2020-09-30
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structure and mechanism of CutA, RNA nucleotidyl transferase with an unusual preference for cytosine.
Nucleic Acids Res., 48, 2020
6YWP
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BU of 6ywp by Molmil
Structure of apo-CutA
Descriptor: CutA, MAGNESIUM ION
Authors:Malik, D, Kobylecki, K, Krawczyk, P, Poznanski, J, Jakielaszek, A, Napiorkowska, A, Dziembowski, A, Tomecki, R, Nowotny, M.
Deposit date:2020-04-29
Release date:2020-08-05
Last modified:2020-09-30
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structure and mechanism of CutA, RNA nucleotidyl transferase with an unusual preference for cytosine.
Nucleic Acids Res., 48, 2020

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