1UWN
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1S1Z
| Photoactivated chromophore conformation in Photoactive Yellow Protein (E46Q mutant) from 10 to 500 nanoseconds | Descriptor: | 4'-HYDROXYCINNAMIC ACID, Photoactive Yellow Protein | Authors: | Anderson, S, Srajer, V, Pahl, R, Rajagopal, S, Schotte, F, Anfinrud, P, Wulff, M, Moffat, K. | Deposit date: | 2004-01-07 | Release date: | 2004-06-15 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Chromophore conformation and the evolution of tertiary structural changes in photoactive yellow protein Structure, 12, 2004
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1UWP
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1TS0
| Structure of the pB1 intermediate from time-resolved Laue crystallography | Descriptor: | 4'-HYDROXYCINNAMIC ACID, Photoactive yellow protein | Authors: | Ihee, H, Rajagopal, S, Srajer, V, Pahl, R, Anderson, S, Schmidt, M, Schotte, F, Anfinrud, P.A, Wulff, M, Moffat, K. | Deposit date: | 2004-06-21 | Release date: | 2005-07-05 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Visualizing reaction pathways in photoactive yellow protein from nanoseconds to seconds. Proc.Natl.Acad.Sci.Usa, 102, 2005
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1S4S
| Reaction Intermediate in the Photocycle of PYP, intermediate occupied between 100 micro-seconds to 5 milli-seconds | Descriptor: | 4'-HYDROXYCINNAMIC ACID, Photoactive yellow protein | Authors: | Schmidt, M, Pahl, R, Srajer, V, Anderson, S, Ren, Z, Ihee, H, Rajagopal, S, Moffat, K. | Deposit date: | 2004-01-17 | Release date: | 2004-04-13 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Protein kinetics: Structures of intermediates and reaction mechanism from time-resolved x-ray data Proc.Natl.Acad.Sci.USA, 101, 2004
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1T1C
| Late intermediate IL3 from time-resolved crystallography of the E46Q mutant of PYP | Descriptor: | 4'-HYDROXYCINNAMIC ACID, Photoactive yellow protein | Authors: | Rajagopal, S, Anderson, S, Srajer, V, Schmidt, M, Pahl, R, Moffat, K. | Deposit date: | 2004-04-15 | Release date: | 2005-01-18 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | A Structural Pathway for Signaling in the E46Q Mutant of Photoactive Yellow Protein Structure, 13, 2005
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3GEC
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3RTY
| Structure of an Enclosed Dimer Formed by The Drosophila Period Protein | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Period circadian protein | Authors: | King, H.A, Hoelz, A, Crane, B.R, Young, M.W. | Deposit date: | 2011-05-04 | Release date: | 2011-12-21 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Structure of an enclosed dimer formed by the Drosophila period protein. J.Mol.Biol., 413, 2011
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4LRY
| Crystal Structure of the E.coli DhaR(N)-DhaK(T79L) complex | Descriptor: | GLYCEROL, PTS-dependent dihydroxyacetone kinase operon regulatory protein, PTS-dependent dihydroxyacetone kinase, ... | Authors: | Shi, R, McDonald, L, Cygler, M, Ekiel, I. | Deposit date: | 2013-07-21 | Release date: | 2014-01-29 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.83 Å) | Cite: | Coiled-Coil Helix Rotation Selects Repressing or Activating State of Transcriptional Regulator DhaR. Structure, 22, 2014
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4LRZ
| Crystal Structure of the E.coli DhaR(N)-DhaL complex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PTS-dependent dihydroxyacetone kinase operon regulatory protein, ... | Authors: | Shi, R, McDonald, L, Cygler, M, Ekiel, I. | Deposit date: | 2013-07-21 | Release date: | 2014-01-29 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | Coiled-Coil Helix Rotation Selects Repressing or Activating State of Transcriptional Regulator DhaR. Structure, 22, 2014
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4LRX
| Crystal Structure of the E.coli DhaR(N)-DhaK complex | Descriptor: | GLYCEROL, PTS-dependent dihydroxyacetone kinase operon regulatory protein, PTS-dependent dihydroxyacetone kinase, ... | Authors: | Shi, R, McDonald, L, Cygler, M, Ekiel, I. | Deposit date: | 2013-07-21 | Release date: | 2014-01-29 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | Coiled-Coil Helix Rotation Selects Repressing or Activating State of Transcriptional Regulator DhaR. Structure, 22, 2014
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1WA9
| Crystal Structure of the PAS repeat region of the Drosophila clock protein PERIOD | Descriptor: | PERIOD CIRCADIAN PROTEIN | Authors: | Yildiz, O, Doi, M, Yujnovsky, I, Cardone, L, Berndt, A, Hennig, S, Schulze, S, Urbanke, C, Sassone-Corsi, P, Wolf, E. | Deposit date: | 2004-10-25 | Release date: | 2005-01-12 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | Crystal Structure and Interactions of the Pas Repeat Region of the Drosophila Clock Protein Period Mol.Cell, 17, 2005
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5XGB
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5NJ8
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8H77
| Hsp90-AhR-p23-XAP2 complex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, AH receptor-interacting protein, Aryl hydrocarbon receptor, ... | Authors: | Wen, Z.L, Zhai, Y.J, Zhu, Y, Sun, F. | Deposit date: | 2022-10-19 | Release date: | 2023-01-04 | Last modified: | 2023-03-22 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cryo-EM structure of the cytosolic AhR complex. Structure, 31, 2023
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8QMO
| Cryo-EM structure of the benzo[a]pyrene-bound Hsp90-XAP2-AHR complex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, AH receptor-interacting protein, Aryl hydrocarbon receptor, ... | Authors: | Kwong, H.S, Grandvuillemin, L, Sirounian, S, Ancelin, A, Lai-Kee-Him, J, Carivenc, C, Lancey, C, Ragan, T.J, Hesketh, E.L, Bourguet, W, Gruszczyk, J. | Deposit date: | 2023-09-24 | Release date: | 2024-01-10 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (2.76 Å) | Cite: | Structural Insights into the Activation of Human Aryl Hydrocarbon Receptor by the Environmental Contaminant Benzo[a]pyrene and Structurally Related Compounds. J.Mol.Biol., 436, 2024
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5V0L
| Crystal structure of the AHR-ARNT heterodimer in complex with the DRE | Descriptor: | Aryl hydrocarbon receptor, Aryl hydrocarbon receptor nuclear translocator, CITRIC ACID, ... | Authors: | Seok, S.-H, Lee, W, Jiang, L, Bradfield, C.A, Xing, Y. | Deposit date: | 2017-02-28 | Release date: | 2017-04-19 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Structural hierarchy controlling dimerization and target DNA recognition in the AHR transcriptional complex. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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7RZW
| CryoEM structure of Arabidopsis thaliana phytochrome B | Descriptor: | 3-[5-[[(3~{R},4~{R})-3-ethyl-4-methyl-5-oxidanylidene-3,4-dihydropyrrol-2-yl]methyl]-2-[[5-[(4-ethyl-3-methyl-5-oxidanylidene-pyrrol-2-yl)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1~{H}-pyrrol-2-yl]methyl]-4-methyl-1~{H}-pyrrol-3-yl]propanoic acid, Phytochrome B | Authors: | Li, H, Burgie, E.S, Vierstra, R.D, Li, H. | Deposit date: | 2021-08-27 | Release date: | 2022-04-13 | Last modified: | 2022-04-20 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Plant phytochrome B is an asymmetric dimer with unique signalling potential. Nature, 604, 2022
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4F3L
| Crystal Structure of the Heterodimeric CLOCK:BMAL1 Transcriptional Activator Complex | Descriptor: | BMAL1b, Circadian locomoter output cycles protein kaput | Authors: | Huang, N, Chelliah, Y, Shan, Y, Taylor, C, Yoo, S, Partch, C, Green, C.B, Zhang, H, Takahashi, J. | Deposit date: | 2012-05-09 | Release date: | 2012-06-06 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.268 Å) | Cite: | Crystal structure of the heterodimeric CLOCK:BMAL1 transcriptional activator complex. Science, 337, 2012
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5SY5
| Crystal Structure of the Heterodimeric NPAS1-ARNT Complex | Descriptor: | Aryl hydrocarbon receptor nuclear translocator, Neuronal PAS domain-containing protein 1 | Authors: | Wu, D, Su, X, Potluri, N, Kim, Y, Rastinejad, F. | Deposit date: | 2016-08-10 | Release date: | 2016-11-09 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.201 Å) | Cite: | NPAS1-ARNT and NPAS3-ARNT crystal structures implicate the bHLH-PAS family as multi-ligand binding transcription factors. Elife, 5, 2016
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5SY7
| Crystal Structure of the Heterodimeric NPAS3-ARNT Complex with HRE DNA | Descriptor: | Aryl hydrocarbon receptor nuclear translocator, DNA (5'-D(*CP*AP*CP*GP*AP*CP*CP*CP*GP*CP*AP*CP*GP*TP*AP*CP*GP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*GP*CP*TP*GP*CP*GP*TP*AP*CP*GP*TP*GP*CP*GP*GP*GP*TP*CP*GP*T)-3'), ... | Authors: | Wu, D, Su, X, Potluri, N, Kim, Y, Rastinejad, F. | Deposit date: | 2016-08-10 | Release date: | 2016-11-09 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (4.2 Å) | Cite: | NPAS1-ARNT and NPAS3-ARNT crystal structures implicate the bHLH-PAS family as multi-ligand binding transcription factors. Elife, 5, 2016
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5XGE
| Crystal structure of the PAS-GGDEF-EAL domain of PA0861 from Pseudomonas aeruginosa in complex with cyclic di-GMP | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Uncharacterized protein PA0861 | Authors: | Liu, C, Liew, C.W, Sreekanth, R, Lescar, J. | Deposit date: | 2017-04-13 | Release date: | 2017-12-20 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (3.31 Å) | Cite: | Insights into Biofilm Dispersal Regulation from the Crystal Structure of the PAS-GGDEF-EAL Region of RbdA from Pseudomonas aeruginosa. J. Bacteriol., 200, 2018
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5XGD
| Crystal structure of the PAS-GGDEF-EAL domain of PA0861 from Pseudomonas aeruginosa in complex with GTP | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Uncharacterized protein PA0861 | Authors: | Liu, C, Liew, C.W, Sreekanth, R, Lescar, J. | Deposit date: | 2017-04-13 | Release date: | 2017-12-20 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Insights into Biofilm Dispersal Regulation from the Crystal Structure of the PAS-GGDEF-EAL Region of RbdA from Pseudomonas aeruginosa. J. Bacteriol., 200, 2018
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7ZUB
| Cryo-EM structure of the indirubin-bound Hsp90-XAP2-AHR complex | Descriptor: | (3~{Z})-3-(3-oxidanylidene-1~{H}-indol-2-ylidene)-1~{H}-indol-2-one, ADENOSINE-5'-DIPHOSPHATE, AH receptor-interacting protein, ... | Authors: | Gruszczyk, J, Savva, C.G, Lai-Kee-Him, J, Bous, J, Ancelin, A, Kwong, H.S, Grandvuillemin, L, Bourguet, W. | Deposit date: | 2022-05-12 | Release date: | 2022-11-23 | Last modified: | 2022-12-07 | Method: | ELECTRON MICROSCOPY (2.85 Å) | Cite: | Cryo-EM structure of the agonist-bound Hsp90-XAP2-AHR cytosolic complex. Nat Commun, 13, 2022
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6E3S
| Crystal Structure of the Heterodimeric HIF-2 Complex with Antagonist PT2385 | Descriptor: | 3-{[(1S)-2,2-difluoro-1-hydroxy-7-(methylsulfonyl)-2,3-dihydro-1H-inden-4-yl]oxy}-5-fluorobenzonitrile, Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1 | Authors: | Wu, D, Su, X, Lu, J, Li, S, Hood, B, Vasile, S, Potluri, N, Diao, X, Kim, Y, Khorasanizadeh, S, Rastinejad, F. | Deposit date: | 2018-07-15 | Release date: | 2019-02-13 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Bidirectional modulation of HIF-2 activity through chemical ligands. Nat. Chem. Biol., 15, 2019
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