4KQS
| Crystal Structure of Farnesyl Pyrophosphate Synthase Mutant (Y204A) Complexed with Mg, Risedronate and Isopentenyl Pyrophosphate | Descriptor: | 1-HYDROXY-2-(3-PYRIDINYL)ETHYLIDENE BIS-PHOSPHONIC ACID, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Farnesyl pyrophosphate synthase, ... | Authors: | Barnett, B.L, Tsoumpra, M.K, Muniz, J.R.C. | Deposit date: | 2013-05-15 | Release date: | 2014-04-30 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Crystal Structure of Farnesyl Pyrophosphate Synthase Mutant (Y204A) Complexed with Mg, Risedronate and Isopentenyl Pyrophosphate To be Published
|
|
3MR3
| Human DNA polymerase eta - DNA ternary complex with the 3'T of a CPD in the active site (TT1) | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(*CP*AP*(TTD)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*CP*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... | Authors: | Biertumpfel, C, Zhao, Y, Ramon-Maiques, S, Gregory, M.T, Lee, J.Y, Yang, W. | Deposit date: | 2010-04-28 | Release date: | 2010-06-30 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structure and mechanism of human DNA polymerase eta. Nature, 465, 2010
|
|
3DHA
| An Ultral High Resolution Structure of N-Acyl Homoserine Lactone Hydrolase with the Product N-Hexanoyl-L-Homoserine Bound at An Alternative Site | Descriptor: | GLYCEROL, N-Acyl Homoserine Lactone Hydrolase, N-hexanoyl-L-homoserine, ... | Authors: | Liu, D, Momb, J, Thomas, P.W, Moulin, A, Petsko, G.A, Fast, W, Ringe, D. | Deposit date: | 2008-06-17 | Release date: | 2008-07-29 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (0.95 Å) | Cite: | Mechanism of the quorum-quenching lactonase (AiiA) from Bacillus thuringiensis. 1. Product-bound structures. Biochemistry, 47, 2008
|
|
4KRT
| |
3MJH
| Crystal Structure of Human Rab5A in complex with the C2H2 Zinc Finger of EEA1 | Descriptor: | Early endosome antigen 1, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Mishra, A.K, Eathiraj, S, Lambright, D.G. | Deposit date: | 2010-04-12 | Release date: | 2010-05-05 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Structural basis for Rab GTPase recognition and endosome tethering by the C2H2 zinc finger of Early Endosomal Autoantigen 1 (EEA1). Proc.Natl.Acad.Sci.USA, 107, 2010
|
|
4KTF
| Crystal structure of Mycobacterium tuberculosis CYP121 in complex with 4,4'-(3-amino-1H-pyrazole-4,5-diyl)diphenol | Descriptor: | 4,4'-(3-amino-1H-pyrazole-4,5-diyl)diphenol, Cytochrome P450 121, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Hudson, S.A. | Deposit date: | 2013-05-20 | Release date: | 2013-07-03 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Overcoming the Limitations of Fragment Merging: Rescuing a Strained Merged Fragment Series Targeting Mycobacterium tuberculosis CYP121. Chemmedchem, 8, 2013
|
|
3MJV
| Structure of A-type Ketoreductases from Modular Polyketide Synthase | Descriptor: | AmphB, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Zheng, J, Taylor, C.A, Piasecki, S.K, Keatinge-Clay, A.T. | Deposit date: | 2010-04-13 | Release date: | 2010-08-18 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.46 Å) | Cite: | Structural and Functional Analysis of A-Type Ketoreductases from the Amphotericin Modular Polyketide Synthase. Structure, 18, 2010
|
|
4KTS
| Bovine trypsin in complex with microviridin J at pH 8.5 | Descriptor: | CALCIUM ION, Cationic trypsin, DI(HYDROXYETHYL)ETHER, ... | Authors: | Quitterer, F, Groll, M, Hertweck, C, Dittmann, E. | Deposit date: | 2013-05-21 | Release date: | 2014-04-02 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Harnessing the evolvability of tricyclic microviridins to dissect protease-inhibitor interactions. Angew.Chem.Int.Ed.Engl., 53, 2014
|
|
4V2R
| Ironing out their differences: Dissecting the structural determinants of a phenylalanine aminomutase and ammonia lyase | Descriptor: | PHENYLALANINE AMINOMUTASE (L-BETA-PHENYLALANINE FORMING) | Authors: | Heberling, M, Masman, M, Bartsch, S, Wybenga, G.G, Dijkstra, B.W, Marrink, S, Janssen, D. | Deposit date: | 2014-10-14 | Release date: | 2014-12-10 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Ironing out their differences: dissecting the structural determinants of a phenylalanine aminomutase and ammonia lyase. ACS Chem. Biol., 10, 2015
|
|
4V48
| Real space refined coordinates of the 30S and 50S subunits fitted into the low resolution cryo-EM map of the initiation-like state of E. coli 70S ribosome | Descriptor: | 16S RIBOSOMAL RNA, 23S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, ... | Authors: | Gao, H, Sengupta, J, Valle, M, Korostelev, A, Eswar, N, Stagg, S.M, Van Roey, P, Agrawal, R.K, Harvey, S.T, Sali, A, Chapman, M.S, Frank, J. | Deposit date: | 2003-05-06 | Release date: | 2014-07-09 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (11.5 Å) | Cite: | Study of the structural dynamics of the E. coli 70S ribosome using real space refinement Cell(Cambridge,Mass.), 113, 2003
|
|
4V4G
| Crystal structure of five 70s ribosomes from Escherichia Coli in complex with protein Y. | Descriptor: | 16S ribosomal RNA, 23S RIBOSOMAL RNA, 30S ribosomal protein S10, ... | Authors: | Vila-Sanjurjo, A, Schuwirth, B.S, Hau, C.W, Cate, J.H. | Deposit date: | 2004-10-06 | Release date: | 2014-07-09 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (11.5 Å) | Cite: | Structural basis for the control of translation initiation during stress. Nat.Struct.Mol.Biol., 11, 2004
|
|
3MS7
| |
4V4U
| The quasi-atomic model of Human Adenovirus type 5 capsid | Descriptor: | HEXON PROTEIN, N-TERMINAL PEPTIDE OF FIBER PROTEIN, PENTON PROTEIN | Authors: | Fabry, C.M.S, Rosa-Calatrava, M, Conway, J.F, Zubieta, C, Cusack, S, Ruigrok, R.W.H, Schoehn, G. | Deposit date: | 2005-03-03 | Release date: | 2014-07-09 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (10 Å) | Cite: | A Quasi-Atomic Model of Human Adenovirus Type 5 Capsid. Embo J., 24, 2005
|
|
4V5Q
| The crystal structure of EF-Tu and G24A-tRNA-Trp bound to a near- cognate codon on the 70S ribosome | Descriptor: | 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... | Authors: | Schmeing, T.M, Voorhees, R.M, Ramakrishnan, V. | Deposit date: | 2010-12-07 | Release date: | 2014-07-09 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | How Mutations in tRNA Distant from the Anticodon Affect the Fidelity of Decoding. Nat.Struct.Mol.Biol., 18, 2011
|
|
4V6W
| Structure of the D. melanogaster 80S ribosome | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 2S ribosomal RNA, ... | Authors: | Anger, A.M, Armache, J.-P, Berninghausen, O, Habeck, M, Subklewe, M, Wilson, D.N, Beckmann, R. | Deposit date: | 2013-02-27 | Release date: | 2014-07-09 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (6 Å) | Cite: | Structures of the human and Drosophila 80S ribosome. Nature, 497, 2013
|
|
4V7N
| Glycocyamine kinase, beta-beta homodimer from marine worm Namalycastis sp., with transition state analog Mg(II)-ADP-NO3-glycocyamine. | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, GUANIDINO ACETATE, Glycocyamine kinase beta chain, ... | Authors: | Lim, K, Pullalarevu, S, Herzberg, O. | Deposit date: | 2009-12-15 | Release date: | 2014-07-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis for the mechanism and substrate specificity of glycocyamine kinase, a phosphagen kinase family member. Biochemistry, 49, 2010
|
|
4V5H
| E.Coli 70s Ribosome Stalled During Translation Of Tnac Leader Peptide. | Descriptor: | 16S RIBOSOMAL RNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... | Authors: | Seidelt, B, Innis, C.A, Wilson, D.N, Gartmann, M, Armache, J, Villa, E, Trabuco, L.G, Becker, T, Mielke, T, Schulten, K, Steitz, T.A, Beckmann, R. | Deposit date: | 2009-10-26 | Release date: | 2014-07-09 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (5.8 Å) | Cite: | Structural insight into nascent polypeptide chain-mediated translational stalling. Science, 326, 2009
|
|
6ACK
| |
4V5Z
| |
4V90
| Thermus thermophilus Ribosome | Descriptor: | 16S RIBOSOMAL RNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... | Authors: | Chen, Y, Feng, S, Kumar, V, Ero, R, Gao, Y.G. | Deposit date: | 2014-02-22 | Release date: | 2014-07-09 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Structure of EF-G-ribosome complex in a pretranslocation state. Nat. Struct. Mol. Biol., 20, 2013
|
|
4V6Q
| Structural characterization of mRNA-tRNA translocation intermediates (class 5 of the six classes) | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Agirrezabala, X, Liao, H, Schreiner, E, Fu, J, Ortiz-Meoz, R.F, Schulten, K, Green, R, Frank, J. | Deposit date: | 2011-12-08 | Release date: | 2014-07-09 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (11.5 Å) | Cite: | Structural characterization of mRNA-tRNA translocation intermediates. Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
4V7H
| Structure of the 80S rRNA and proteins and P/E tRNA for eukaryotic ribosome based on cryo-EM map of Thermomyces lanuginosus ribosome at 8.9A resolution | Descriptor: | 18S rRNA, 26S ribosomal RNA, 40S ribosomal protein S0(A), ... | Authors: | Taylor, D.J, Devkota, B, Huang, A.D, Topf, M, Narayanan, E, Sali, A, Harvey, S.C, Frank, J. | Deposit date: | 2009-09-22 | Release date: | 2014-07-09 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (8.9 Å) | Cite: | Comprehensive molecular structure of the eukaryotic ribosome. Structure, 17, 2009
|
|
7TD3
| Sphingosine-1-phosphate receptor 1-Gi complex bound to S1P | Descriptor: | (2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Liu, S, Paknejad, N, Zhu, L, Kihara, Y, Ray, D, Chun, J, Liu, W, Hite, R.K, Huang, X.Y. | Deposit date: | 2021-12-30 | Release date: | 2022-02-09 | Last modified: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Differential activation mechanisms of lipid GPCRs by lysophosphatidic acid and sphingosine 1-phosphate. Nat Commun, 13, 2022
|
|
4WI5
| Structural mapping of the human IgG1 binding site for FcRn: hu3S193 Fc mutation H310A | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region | Authors: | Farrugia, W, Burvenich, I.J.G, Scott, A.M, Ramsland, P.A. | Deposit date: | 2014-09-25 | Release date: | 2015-09-30 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural and functional mapping of human IgG1 binding site for FcRn in vivo using human FcRn transgenic mice To Be Published
|
|
4WJG
| Structure of T. brucei haptoglobin-hemoglobin receptor binding to human haptoglobin-hemoglobin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Haptoglobin, ... | Authors: | Stoedkilde, K, Torvund-Jensen, M, Moestrup, S.K, Andersen, C.B.F. | Deposit date: | 2014-09-30 | Release date: | 2014-11-26 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural basis for trypanosomal haem acquisition and susceptibility to the host innate immune system. Nat Commun, 5, 2014
|
|